试析He-Ne激光沿经络自动照射仪的应用

本文介绍He-Ne激光沿经络自动照射仪的结构、特点,分析了激光与组织相互作用的物理效应和生物效应,提出了该仪器在针灸临床中的应用。     

初治颈淋巴结转移喉癌颈清除术后的预后相关因素

目的：探讨颈淋巴结转移（cN＋）喉癌颈清除术后颈部复发相关因素、治疗及预后情况。方法：回顾性研究1992～1999年我院收治的cN＋喉癌行颈清除术53例，对其颈部复发率、复发时间、淋巴结分布、局部治疗、复发影响因素及预后进行探讨。结果：cN＋喉癌颈清除术后颈部复发率为24．53％（13／53）；3和5年生存率为39．62％和35．52％，颈部复发组生存率与无复发组相比，差异无统计学意义，P=0．6717；复发主要位于清除侧颈部（9／13），复发淋巴结位于Ⅱ、Ⅲ和Ⅳ区84．62%（11/13）；颈部复发多在18个月内（12／13）；颈部复发行挽救手术者治疗效果好。病理分化程度（P=0．6717）、病变部位（P=0．966）、临床分期（P=0．244）、初治颈清除术式（P=0．579）、颈清除术后颈部是否放疗（P=0．457）不影响颈部复发率，N分期（P=0．042）影响颈部复发。结论：cN＋喉癌颈清除术后颈部有无复发与生存率无关；复发多位于行颈清除术侧颈部（Ⅱ、Ⅲ和Ⅳ区）；N分期影响颈部复发；出现颈部复发者行挽救手术治疗效果好。     

140例住院精神病患者苯二氮(艹卓)类药物使用情况分析

目的:了解我院住院精神病患者苯二氮(艹卓)类药物(BDZ)使用情况.方法:填写BDZ使用监测表,对586例住院精神病患者BDZ使用情况进行回顾性分析.结果:住院精神病患者合并使用BDZ占23.9%,其中发生依赖为32.1%.BDZ用于镇静催眠占82.9%;使用种类以氯硝安定为多,占74.3%;BDZ合并抗精神病药物(APD)以利培酮为多,占25.7%.结论:住院精神病患者BDZ的用药剂量及用药原因是合理的,但不宜长期使用.     

抗焦虑药物对束缚应激大鼠作用的分子机制探索

目的：为了探讨抗焦虑药物治疗焦虑症状的分子作用机制。方法：建立大鼠束缚应激模型，观察抗焦虑药物帕罗西汀用药组大鼠的旷场行为和下丘脑c-fos的表达。结果：与正常对照组比较，应激大鼠在旷场中的穿行格数和直立次数明显增加，下丘脑室旁核c-fos表达显著增加，而帕罗西汀用药组能减少大鼠在旷场中的活动和下丘脑室旁核c-fos表达。结论：帕罗西汀对束缚应激大鼠脑保护作用可能与下调c-fos基因表达有关。     

[THIS ARTICLE HAS BEEN RETRACTED]Vitreous function and intervention of it with vitrectomy and other modalities

The vitreous body, the largest intraocular component, plays a key role in eye development, refraction, cell barrier function, oxygen metabolism and the pathogenesis of assorted diseases. Age, refraction and systemic diseases can cause vitreous metabolic abnormalities. With the continuous development of vitrectomy techniques and equipment, vitreous injections and vitrectomies have increased over the recent decades. However, the normal oxygen tension gradient in the vitreous helps to protect the lens and anterior chamber angle from oxidative stress damage, whereas the increased vitreous oxygen tension around lens and the trabecular meshwork after vitrectomy may lead to postoperative nuclear cataract and a high incidence of open angle glaucoma. As a conventional procedure, scleral buckling holds several advantages over vitrectomy in selected cases. This review raises concerns regarding the function of the vitreous, and encourages conducting vitreous interventions prudently.     

高位复杂性肛瘘的治疗进展

阐述了在治疗高位复杂性肛瘘方面的新方法和技术，介绍了改良的挂线术、保留括约肌的术式和封堵注入术的治疗方法和效果。改良的挂线引流术式仍是治疗高位复杂性肛瘘的主要方法；新近出现的保留括约肌的手术方法为减少肛门功能失禁、彻底治疗高位复杂性肛瘘提供了可能；封堵填充术因其操作简单、较好的治愈率等特点正成为非手术治疗的主要方法。     

Inhibition of Erythroid Differentiation of Human Leukemia K562 Cells by N-acetylcysteine and Ascorbic Acid through Downregulation of ROS

正This study investigated the effects of N-acetylcysteine(NAC)and ascorbic acid(AA)on hemin-induced K562 cell erythroid differentiation and the role of reactive oxygen species(ROS)in this process.Hemin increased ROS levels in a concentration-dependent manner,whereas NAC and AA had opposite effects.Both NAC and AA eliminated transient increased ROS levels after hemin treatment,inhibited hemin-induced     

Treatment strategy of intracranial arachnoid cysts

<正>Objective To evaluate the long-term facial nerve funtion of patients following microsurgical removal of large and huge acoustic neuroma,and to indentify the factors that influence these outcomes. Methods A retrospective review was performed,which included 176 consecutive patients with a large