结肠非低张双重造影的应用

本文应用结肠非低张双重对比灌肠造影诊断结肠病变,这是一种简单的方法。本文根据150例的实践径验介绍了技术、病人的准备、有关造影剂的问题和正常所见,并通过具体的病例阐述了结肠非低张双重对比检查的临床应用价值,并指出了本法的不足之处。     

PRENATAL DIAGNOSIS Ⅰ. EARLY DIAGNOSIS OF OPEN NEURAL TUBE DEFECTS BY QUALITATIVE ACETYLCHOLINESTERASE ISOENZYME IN AMNIOTIC FLUID

The measurement of amniotic fluid (AF) acetylcholinesterase isoenzyme (AChEI) is a relatively new method for early diagnosis of open neural tube defects (NTDs). As quantitative methods are of unproven reliability at present, the authors used a high resolving power qualitative method-vertical slab polyaerylamide gel electrophoresis. The benefits of this technique are: simplicity of operation, accuracy, unsophisticated equipment, and easily available reagents. Combined results of 9 NTDs studies revealed that samples from early pregnancy gave more accurate results than those from late pregnancy.     

萘普生对大鼠着床期宫内PGF_(2α)含量及宫内节育器抗生育作用的影响

本文测定了对照组及两个萘普生(前列腺素合成酶抑制剂)处理组大鼠着床期宫内PGF2α的含量。结果表明,对照组、萘普生低剂量组(2mg/kg体重)和高剂量组(20mg/kg体重)的PGF2α含量分别为6.71±0.93、2.19±0.34和1.01±0.18ng/100g组织(三组间P<0.01)。同时,还观察到在本实验条件下,萘普生无明显干扰节育器抗生育作用,药物本身亦未呈现显著抗生育活性。     

新医改促动中国医疗器械市场竞争——CMEF 2009深圳见闻

编者按:第61届中国国际医疗器械博览会(简称医博会或CMEF)、第8届中国国际医疗器械设计与制造技术展览会(简称ICMD)于4月18～21日在深圳举行.本届CMEF设置标准展位5100多个,展出面积110000m2,参展企业2100余家,观众120000人次,36家国内展团、17家国家展团.除了原已开辟的医学影像区(CMEF Imaging)、体外诊断区(CMEF IVD)、医用电子仪器区、医用光学仪器区、医院设备区和医疗软技术(Medisoft)等专业分区以外,本届CMEF IT展区作为CMEF中新的专业分区,浓缩了医院信息化产业的发展进程,集中展示了医院信息化领域的最新技术.伴随新医改方案的出台,本次医博会弥漫着新一轮市场搏杀的硝烟.     

我们对发生在急诊科的死亡病例了解多少？

目的：通过尸体解剖检查结果来观测临床死亡诊断与实际死凶之间的差异，本研究中的死亡病例均发生在急诊科并向苏格兰地方检查院上报，随后进行尸检。方法：这是在格拉斯哥某医院急诊科进行的一个为期1年的前瞻性研究，所有入选病例系来院前死亡和在急诊科死亡的患者。由有经验的急诊科医师在场判断死亡原因，然后与尸枪结果确定的真正死因进行对照，比较两者之间的差异。     

Interrupting reperfusion as a stroke therapy: ischemic postconditioning reduces infarct size after focal ischemia in rats.

Cerebral ischemic preconditioning protects against stroke, but is clinically feasible only when the occurrence of stroke is predictable. Reperfusion plays a critical role in cerebral injury after stroke; we tested the hypothesis that interrupting reperfusion lessens ischemic injury. We found for the first time that such postconditioning with a series of mechanical interruptions of reperfusion significantly reduces ischemic damage. Focal ischemia was generated by permanent distal middle cerebral artery (MCA) occlusion plus transient bilateral common carotid artery (CCA) occlusion. After 30 secs of CCA reperfusion, ischemic postconditioning was performed by occluding CCAs for 10 secs, and then allowing for another two cycles of 30 secs of reperfusion and 10 secs of CCA occlusion. Infarct size was measured 2 days later. Cerebral blood flow (CBF) was measured in animals subjected to permanent MCA occlusion plus 15 mins of bilateral CCA occlusion, which demonstrates that postconditioning disturbed the early hyperemia immediately after reperfusion. Postconditioning dose dependently reduced infarct size in animals subjected to permanent MCA occlusion combined with 15, 30, and 60 mins of bilateral CCA occlusion, by reducing infarct size approximately 80%, 51%, and 17%, respectively. In addition, postconditioning blocked terminal deoxynucleotidyl transferase-mediated uridine 5'-triphosphate-biotin nick end labeling-positive staining, a marker of apoptosis, in the penumbra 2 days after stroke. Furthermore, in situ superoxide detection using hydroethidine suggested that postconditioning attenuated superoxide products during early reperfusion after stroke. In conclusion, postconditioning reduced infarct size, most plausibly by blocking apoptosis and free radical generation. With further study it may eventually be clinically applicable for stroke treatment.