进一步重视脂肪新功能对创面愈合作用的研究

创面愈合的研究范围正随着相关领域的研究进展而不断拓展和完善。以皮下脂肪组织为例 ,以往多数的研究认为 ,脂肪组织来源于间充质细胞 (mesenchymalcell,MC) ,其功能仅是一个能量贮存仓库。但近年来的研究表明 ,脂肪组织还可能是一个重要的内分泌器官 ,在发育学、信号转导 ,以及干细胞作用等多方面与组织修复存在着密切联系。有专家认为 ,加强对脂肪细胞新功能的研究和开发 ,有可能对创面修复和组织再生机制产生新的认识 ,并寻找出新的促愈合手段。脂肪细胞参与创面愈合首先表现在它可能作为一个内分泌器官。迄今为止 ,已经发现人的脂肪细…     

水飞蓟素对脑缺血性损伤的影响

目的：探讨水飞蓟素对脑缺血性损伤保护作用的机制。方法：采用四血管阻断法造成大鼠全脑缺血模型．观察水飞蓟素对脑匀浆液一氧化氮(NO)和一氧化氮合成酶(NOS)的表达量。结果：水飞蓟素在显降低缺血大鼠脑组织中NO、NOS含量的同时，明显缩小了梗死面积。结论：水飞蓟素能提高机体抗氧化能力，对脑缺血损伤有显的保护作用。     

钕激光照射对大鼠肿瘤生长的抑制作用

目的:研究钕激光照射对大鼠肿瘤生长的抑制作用.方法:采用钕激光在实验组荷瘤大鼠的肿瘤区及其肿瘤区周围进行照射,并观察抑制肿瘤的效果.结果:实验组大鼠肿瘤体的生长速度明显慢于对照组大鼠肿瘤体的生长速度.结论:用钕激光照射对抑制癌肿瘤的生长速度有明显的作用.     

碘杂环化合物对离体豚鼠心乳头肌动作电位和收缩力的作用

采用细胞内微电极记录技术,同步观察了3,6-[二甲氨基]-二苯并碘因甲酸盐(IHC-64)对豚鼠心乳头肌细胞动作电位和收缩力的作用。50μmol/L IHC-64抑制心肌收缩力,而不影响快反应动作电位。增加IHC-64浓度,动作电位0相最大峰值(APA)、除极速率(dp/dt_(max))和复极50％和90％时程(APD_(50)、APD_(90))被明显抑制。IHC-64抑制慢反应动作电位,提高细胞外钙浓度可拮抗这种抑制。结果提示,IHC-64主要抑制慢Ca~(2+)内流,同时也部分抑制快Na~+内流,它可能是一种新型B类钙通道阻滞剂。     

超声对胰腺移植术后的监测作用

目的探讨二维超声和彩色多普勒血流显像（cDFI）对移植胰腺的功能和术后并发症的监测作用。方法用彩色多普勒超声观察6例移植胰腺的形态和血流动力学变化情况。结果（1）功能正常的移植胰腺在术后形态正常，体积偏大，主胰管内径正常，实质回声较正常胰腺略高，动脉PSV13～64cm/s，R10.44～0.68，P10.67～2.33。（2）2例出现急性排异和1例出现移植胰腺炎的移植胰腺周边出现低或无回声区，实质回声明显减低，分布不均。1例急性重度排异的RI值超过0.9，而另1例急性轻度排异RI值小于0.7。1例移植胰腺炎RI值超过0.9，PI值超过4.0。结论CDFI作为一种无创的检查技术对胰腺移植术后的监测和诊治具有积极意义。     

出土文献与彭祖养生学术研究

彭祖是我国古代的"寿星",随着一系列的考古发现,如汉早期马王堆墓《十问》篇、张家山汉墓《引书》篇,尤其是上海博物馆藏竹简(三)有《彭祖》篇,改变了我们对彭祖学术的认识,不仅为证明楚国产生并流传黄老学派思想提供了佐证,而且在学术史领域提供了新的课题,进一步廓清了彭祖养生学术之源乃是古代巫术,其流是在春秋战国秦汉时期被诸子传诵,与道家等流派结合,具有神仙色彩,最终被汉末魏晋道家改造为神仙方术。     

Longitudinal Analysis of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibody in SARS Patients

The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.     

Proteasome Inhibitors Sensitize Hepatocellular Carcinoma Cells to TRAIL

A poptosis, an evolutionarily conserved form of cell suicide, oc- curs in two physiological stages: commitment and execution.[1] It has been found that several Bcl-2 family proteins are located in the outer mitochondrial membrane, where they control relea…     

The role of endotoxin in the pathogenesis of experimental multiple system organ failure: a preliminary report.

In this study, an animal model of multiple system organ failure (MSOF) in rabbits, engendered by feeding E. coli prior to severe hemorrhagic shock, was used for the purpose of investigating 1) the relationship between lipopolysaccharide (LPS) and MSOF, and 2) the effectiveness of Re-LPS antiserum in preventing MSOF. The results showed that endotoxemia occurred very early, and its degree correlated well with that of organ dysfunction. Re-LPS antiserum administration abated the toxic effects and lowered the incidence of MSOF. These results suggest that sequential analysis of circulating LPS levels may be useful for the early diagnosis of MSOF, and that gut-derived endotoxin might play an important role in the pathogenesis of experimental MSOF.