<Emphasis Type="Italic">PRSS1</Emphasis> (R122H) mutation in an Indian family with low penetrance is associated with pancreatitis phenotype

Mutations in PRSS1 gene namely R122H and N29I cause hereditary pancreatitis. They are autosomal dominant with a high penetrance (80%) reported in North American, North-east Asian, and North European ethnicities. However, the mutations are reportedly absent in Indian, African, and South American ethnicities. We report here for the first time a family from India that is positive for R122H mutation in the PRSS1 gene. The proband is symptomatic with chronic pancreatitis, however, the father although heterozygous for R122H is asymptomatic.     

Ideology in medical science: class in the clinic

The class character of medicine is most easily discerned in the inequitable organization of health services. Capital's shaping of the patterns of disease and our medical/scientific responses is less apparent but equally strong. We illustrate this point by reviewing some recent history of cardiovascular diseases and therapies. Hitherto unknown afflictions have become commonplace. Our diagnostic and therapeutic concepts are the crystallization of a long history of scientific effort--an effort dominated and directed by capitalist imperatives. The work of the clinician rests on this scientific substrate, and recognition or rejection of its class nature provides a potential basis for a new medical science but not the needed results. The socialist transformation of medicine will require a recognition of the capitalist specificity of current science, and the painstaking construction of alternative modes of thought.     

Public money, private control: a case study of hospital financing in Oakland and Berkeley, California

Government support of public and private hospitals in Oakland and Berkeley, California was investigated. The private hospitals received government subsidies amounting to at least 60 per cent of their total revenues. The dollar amount of the subsidies to private hospitals was four and one-half times greater than government expenditures on the public hospital. In Oakland and Berkeley, as in many cities, public medical services have been reduced while both government health expenditures and private hospital revenues have increased sharply. The private hospitals, although all nominally non-profit, exhibit revenue maximizing behavior which results in socially unjust and medically irrational resource allocation. Funds might be found for public hospitals and clinics, and resources allocated more justly and rationally, if government expenditures in the private sector were brought under greater public scrutiny and control.     

Discounting the debtors will not make medical bankruptcy disappear

David Dranove and Michael Millenson seem determined to deny that financial fallout from illness pushes middle-class families into bankruptcy. Anxious to erase the headline that three-quarters of U.S. medical bankrupts had health insurance at the onset of their illnesses and the resulting spotlight on inadequate coverage and insurance cancellation practices, they ignore most of our data and misrepresent the rest. They dismiss families' explanations of their difficulties and blame those ruined by illness for their own problems. However, the data from the bankruptcy courts are undeniable. Bankruptcies affect mainly middle-class, privately insured families, and about half are triggered, at least in part, by illnesses.     

Sources of U.S. Physician Income: The Contribution of Government Payments to the Specialist–Generalist Income Gap

Background  Physician income varies threefold among specialties. Lower incomes have produced shortages in primary care fields. Objective  To investigate the impact of government policy on generating income differentials among specialties. Design and Participants  Cross-sectional analysis of the 2004 MEPS. Measurements  For outpatient care, total payments made to 27 different types of specialists from five types of payers: Medicare, Medicaid, other government (the Veterans Administration and other state and local programs), private insurance, and out-of-pocket payments. For inpatient care, aggregate (i.e., all-specialty) inpatient physician reimbursement from the five payers. Results  In 2004, physicians derived 78.6% of their practice income ($149,684 million, 95% CI, $140,784 million—$158,584 million) from outpatient sources and 21.4% of their income ($40,782 million, 95% CI, $36,839 million—$44,724 million) from inpatient sources. Government payers accounted for 32.7% of total physician income. Four specialties derived > 50% of their outpatient income from public sources, including both the lowest and highest paid specialties (geriatrics and hematology/oncology, respectively). Conclusions  Inter-specialty income differences result, in part, from government decisions. Electronic supplementary material  The online version of this article (doi:) contains supplementary material, which is available to authorized users.