全文获取类型
收费全文 | 925篇 |
免费 | 48篇 |
国内免费 | 60篇 |
专业分类
儿科学 | 45篇 |
妇产科学 | 6篇 |
基础医学 | 67篇 |
口腔科学 | 13篇 |
临床医学 | 148篇 |
内科学 | 291篇 |
皮肤病学 | 25篇 |
神经病学 | 12篇 |
特种医学 | 239篇 |
外科学 | 37篇 |
综合类 | 31篇 |
预防医学 | 58篇 |
眼科学 | 8篇 |
药学 | 31篇 |
中国医学 | 2篇 |
肿瘤学 | 20篇 |
出版年
2022年 | 3篇 |
2021年 | 11篇 |
2020年 | 6篇 |
2019年 | 4篇 |
2018年 | 13篇 |
2017年 | 3篇 |
2016年 | 2篇 |
2015年 | 15篇 |
2014年 | 21篇 |
2013年 | 28篇 |
2012年 | 19篇 |
2011年 | 31篇 |
2010年 | 28篇 |
2009年 | 27篇 |
2008年 | 24篇 |
2007年 | 54篇 |
2006年 | 21篇 |
2005年 | 23篇 |
2004年 | 23篇 |
2003年 | 18篇 |
2002年 | 11篇 |
2001年 | 15篇 |
2000年 | 9篇 |
1999年 | 14篇 |
1998年 | 53篇 |
1997年 | 36篇 |
1996年 | 59篇 |
1995年 | 46篇 |
1994年 | 40篇 |
1993年 | 49篇 |
1992年 | 12篇 |
1991年 | 10篇 |
1990年 | 19篇 |
1989年 | 33篇 |
1988年 | 34篇 |
1987年 | 34篇 |
1986年 | 25篇 |
1985年 | 30篇 |
1984年 | 16篇 |
1983年 | 10篇 |
1982年 | 12篇 |
1981年 | 22篇 |
1980年 | 19篇 |
1979年 | 6篇 |
1978年 | 9篇 |
1977年 | 15篇 |
1976年 | 7篇 |
1975年 | 9篇 |
1965年 | 2篇 |
1963年 | 1篇 |
排序方式: 共有1033条查询结果,搜索用时 31 毫秒
61.
Multiple myeloma: evaluation by CT 总被引:3,自引:0,他引:3
Although patients who have multiple myeloma usually have straightforward clinical symptoms and corroborative radiographs, in some instances, these patients will present atypically, with symptoms suggesting active disease but radiographs that are normal or nonspecific. We reviewed the records of 32 patients who had documented multiple myeloma and had undergone CT examinations, assessing the value of those examinations. Although CT is not indicated in all patients who have multiple myeloma, it is especially useful in patients who have bone pain and normal or nonspecific radiographs. CT provided confirmatory information in all cases in which lesions were seen on radiographs. CT also frequently demonstrated a greater extent of disease than could be appreciated on the radiographs. 相似文献
62.
63.
Insufficiency fractures in the supraacetabular region were identified in five women, aged 55-83 years. Factors contributing to the diminished resistance of their bones included postmenopausal osteoporosis, steroid therapy, radiation therapy, and rheumatoid arthritis. The supraacetabular fractures were seen on routine radiographs as hazy bands of sclerosis located immediately above and parallel to the acetabular roof. All five patients had additional fractures in the spine or pelvis. Supraacetabular insufficiency fractures may be an unsuspected cause of hip pain, especially in older women. 相似文献
64.
65.
66.
LeRoy AJ; Williams HJ Jr; Bender CE; Segura JW; Patterson DE; Benson RC 《Radiology》1985,155(1):83-85
Two patients had colonic perforation as a result of percutaneous nephrostomy placement followed by track dilatation and renal calculus removal. We present the technical aspects of nephrostomy placement and stone removal, as well as the clinical diagnosis and management of these cases. Both patients recovered well with conservative therapy and required no surgical intervention. This report reviews the anatomic considerations for percutaneous nephrostomy in patients undergoing renal stone removal. 相似文献
67.
Arterial hypertension is a major cause of morbidity and mortalitybecause of its association with coronary heart disease, cerebrovasculardisease and renal disease. The extent of target organ involvement(i.e. heart, brain and kidneys) determines outcome. North Americanstudies have shown that hypertension is a major contributorto 500 000 strokes (250 000 deaths) and 1 000 000 myocardialinfarctions (500 000 deaths) per annum. 相似文献
68.
The surgical hypertensive patient 总被引:1,自引:0,他引:1
We reviewed the pathophysiology and treatment of hypertensionin a recent edition of this journal (see key references). Inthis article, we discuss the management of the hypertensivepatient presenting for surgery and anaesthesia. 相似文献
69.
Analysis of an IS2404-based nested PCR for diagnosis of Buruli ulcer disease in regions of Ghana where the disease is endemic
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Stienstra Y van der Werf TS Guarner J Raghunathan PL Spotts Whitney EA van der Graaf WT Asamoa K Tappero JW Ashford DA King CH 《Journal of clinical microbiology》2003,41(2):794-797
Mycobacterium ulcerans causes Buruli ulcer disease (BUD), an ulcerative skin disease emerging mainly in West Africa. Laboratory confirmation of BUD is complicated as no "gold standard" for diagnosis exists. A nested primer PCR based on IS2404 has shown promise as a diagnostic assay. We evaluated the IS2404-based PCR to detect M. ulcerans DNA in tissue specimens from 143 BUD patients diagnosed according to the World Health Organization BUD clinical case definition in Ghana. Comparisons were made with culture and histopathology results. Variables influencing detection rate tested in this PCR protocol included the amount of tissue used and the stage of disease. The nested PCR was repeated on DNA extracted from a different part of the same biopsy specimen of 21 culture-positive samples. Of all 143 specimens, 107 (74.8%; 95% confidence interval, 68 to 82%) showed the presence of M. ulcerans DNA by PCR. Of the 78 histology-confirmed BUD patient samples, 64 (83%) were PCR positive. Detection rates were influenced neither by the amount of tissue processed for PCR nor by the stage of disease (preulcerative or ulcerative). Taken together, the two nested PCR tests on the subset of 21 culture-positive samples were able to detect M. ulcerans DNA in all 21 culture-confirmed patients. For future studies, small tissue samples, e.g., punch biopsy samples, might be sufficient for case confirmation. 相似文献
70.
Sejvar J Bancroft E Winthrop K Bettinger J Bajani M Bragg S Shutt K Kaiser R Marano N Popovic T Tappero J Ashford D Mascola L Vugia D Perkins B Rosenstein N;Eco-Challenge Investigation Team 《Emerging infectious diseases》2003,9(6):702-707
Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in "Eco-Challenge" multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis. 相似文献