血管紧张素Ⅱ受体—1在清醒大鼠血压波动性调节中的作用

目的：探讨血管紧张素Ⅱ受体－１（ＡＴ１受体）在清醒ＷＫＹ大鼠和自发性高血压大鼠（ＳＨＲ）血压波动性（ＢＰＶ）调节的作用。方法：应用计算机化清醒自由活动大鼠血流动力学监测技术，分别观察了：（１）静注新型非肽类ＡＴ１受体拮抗剂Ｌｏｓａｒｔａｎ（Ｌｏｓ）；９２）静注神经节阻断剂氯异朵铵；（３）静注Ｃｈｌｏｒ和Ｌｏｓ；（４）静滴血管紧张素Ⅱ（ＡＮＧⅡ）及静注Ｃｈｌｏｒ后静滴ＡＮＧⅡ对ＷＫＹ大鼠和ＳＨＲ血压     

Prognostic significance of cytochemical analysis of leukemic M2 blasts

Cytochemical analysis of leukemic blasts from 46 patients with acute myeloblastic M2 leukemia (according to the FAB classification) was performed before and after cytostatic therapy, and compared with findings obtained in 20 age- and sex-matched control subjects. Cytochemical findings for myeloperoxidase (MPO), Sudan black B, acid phosphatase and alpha-naphthyl-acetate esterase (ANAE) were related to the achievement of the first complete remission (CR),i.e. data were compared after the patients had been divided into CR and non-CR groups. The analysis clearly showed that a high proportion of myeloperoxidase- and, to a lesser extent, Sudan black B-positive blasts before treatment may have constituted a significantly unfavourable prognostic factor.     

北京、广州、上海城市居民营养知识、态度、行为的调查

对北京、广州和上海三大城市随机抽取的９６５名年龄在２０～５０岁的城市居民进行有关营养知识、态度和行为（Ｋ－Ａ－Ｐ）的调查。结果显示，三地区调查对象的营养知识水平不高。营养知识的得分与其自身受教育程度有相关性（ｒ＝０．３０１１，Ｐ＜０．０１）。年龄在３５岁以上的对象，营养知识的得分高于年轻人；三地区调查对象对营养知识的获取，合理的膳食模式，卫生的饮食习惯均持有积极、肯定的态度。食物消费频度调查结果表明，米／面、肉／禽、蔬菜、水果、奶及奶制品的消费量较高。此外，８９．５％，７８．８％和４７．８％的调查对象分别选择报纸、电视、广播作为其主要营养信息来源。本次调查为将来的营养宣教的内容和方法提供依据。     

Coronary permeability and left ventricular function following thrombolytic therapy

We study 40 patients, 55 +/- 7 years old with acute myocardial infarction treated early by thrombolytic therapy (20 STK and 20 rt-PA). All patients were angiographically studied in the following conditions: 1) baseline, before initiating therapy. 2) Three hours after treatment. 3) Twenty four hours later. 4) Before discharge. The infarct related artery was patent 24 hours after treatment in 31 patients (78%); five of them were patent before treatment, and we observed an early reperfusion in 20 patients (57%) and late reperfusion in 6 patients (17%). The number of patients with angiographic evidence of intraluminal thrombus decreased progressively through conditions while the grade TIMI of coronary perfusion increased in the absence of reocclusion. Final regional wall motion of infarct related myocardial zones and their degree of recovery were significantly higher in recanalized patients, as compared with non-reperfused patients. Similarly, left ventricular functional recovery was higher in patients with antegrade of collateral flow to the infarct area, as compared with totally occluded patients.     

围产儿与儿童胸腺的病理改变

The most outstanding pathological changes of perinatal babies and children, based on the review of the autopsy files in the 1st Affiliated Hospital of West China University of Medical Sciences, are lymphocytic depletion, and reticuloepithelial cell swelling and/or fusiform malformation in the cortex, while in the medulla apoptosis is more prominent. We suppose that these alterations are due to immaturity of cortical thymocytes, and in the diseased condition, they are easily affected by extraordinary factors, especially the influence of corticosterone inducing acute severe necrosis, so the number of lymphocytes are obviously diminished. But, in the medulla, as intact mature lymphocytes exist, physiological phenomenon such as apoptosis is rather prominent in it. While in the medulla, Hassall's corpuscles have various characteristic changes, such as cornification, calcification, fusion, cystic change and disintegration. Besides, we observed a new alteration in the thymus defined as vacuolization. All the above pathological changes reached the peak in the 28- day group; there after, they might become either worse or better according to the condition of the disease and growth of the body. However, these are still problems to be further studied separately.     

卫生院改革中的"软法"运行现状及功能实现

乡镇卫生院改革是一项关乎农村稳定、农民安康的工程。从既有的工作轨迹及发展趋势来看,这项改革是在以“两办(中共中央办公厅、国务院办公     

云南白药与维生素K4治疗肺结核少量咯血80例

咯血是肺结核最常见的并发症之一，多见于初、复治的Ⅲ型肺结核病人，尤其是有空洞形成者。笔者近10年来采用云南白药(或云南白药胶囊)与维生素K4联合治疗初、复治肺结核引起少量咯血的病人，收到了较理想的效果，报告如下。     

家庭暴力及其应对策略

近几十年来，公众和社会逐渐认识到家庭暴力是一种主要的公共健康问题，它影响着不同种族、不同社会、不同经济背景中的个体。目前家庭暴力依然是当今社会中的一大问题。结束家庭暴力要求全体社会的共同关注，包括卫生保障部门、执法部门、社会服务系统联合起来应对家庭暴力。