子宫肌瘤的血供分型及其对栓塞治疗的指导意义

目的 分析子宫肌瘤的血供特征并提出血管造影分型、探讨血供分型对于栓塞的指导意义。方法 50例资料完整、血管造影显示清晰的子宫肌瘤病例,采用Dextran微球子宫动脉栓塞。栓塞前,先作双侧选择性的髂内和子宫动脉血管造影,分析血管造影图像以确定双侧子宫动脉对子宫和子宫肌瘤的血供、血供比例、子宫动脉的跨中线吻合和卵巢实质显影等情况。结果 按照双侧子宫动脉对子宫肌瘤的不同供血比例可将之分为3型：单侧供血型、一侧优势型和双侧均势型。50例中,这3型的比例分别为6％（3例,1例右侧,2例左侧）、84％（42例,左右侧优势各21例）和10％（5例）。双侧子宫动脉间存在明显吻合者5例、发现副子宫动脉者2例。有15例可见子宫动脉的卵巢支显影及卵巢实质染色,而通过卵巢血管吻合逆行显示同侧卵巢动脉者为5例,占10％。结论 应倡导个体化的子宫肌瘤动脉栓塞策略。根据两侧子宫动脉对子宫肌瘤的不同供血比例合理分配微球栓塞剂。当造影看到卵巢动脉显影时,则宜选择直径大于350μm的微球作子宫动脉栓塞,以保护卵巢功能。     

正常人亮暗背景下不同对比度的视力变化

目的:观察正常人眼在亮、暗背景下不同对比度的视力变化.方法:54例(108眼)正常视力的成年男性,用多功能电子视力测量仪(MFVA-100)比较亮、暗背景下不同对比度(100%、25%、10%、5%)的logMAR视力,并分析亮、暗背景下视力的相关性.结果:背景亮度相同时,随对比度的下降各组视力呈下降趋势,低对比度组视力明显低于高对比度组(P＜0.001);对比度相同时,暗背景组视力明显低于亮背景组(P＜0.001).亮背景100%对比度组视力与暗背景各组视力之间均无线性相关,与亮背景25%、10%、5%对比度组视力呈正线性相关(P＜0.001);暗背景100%对比度组与暗背景25%、10%、5%对比度组视力呈正线性相关(P＜0.001).随着对比度的降低,各组视力的波动幅度增加,暗背景下对比度5%时差异最大.结论:正常人眼亮背景下的视力优于暗背景,随着对比度降低,视力渐趋下降,个体差异增加,亮、暗背景之间的视力变化无线性相关.     

雄激素受体对从前列腺癌LNCaP细胞分选出的CK5 +CK8 +细胞的作用及其调控机制

目的:探讨雄激素受体（AR）对从前列腺癌LNCaP细胞中分选出的CK5 +CK8 +细胞的作用及其调控机制。 方法:采用流式细胞术从LNCaP细胞中分选CK5 +CK8 +细胞,使用慢病毒载体携带AR基因转入CK5 +CK8 +细胞。实验...     

Photoluminescence nonlinearity and picosecond transient absorption in an LYSO:Ce scintillator excited by a 266 nm ultraviolet laser

Lutetium–yttrium oxyorthosilicate doped with cerium (LYSO:Ce) is a widely used scintillator, and the study of its nonlinear behavior under high excitation density is very significant owing to its direct influence on radiation measurements. Using a 266 nm ultraviolet laser to excite an LYSO:Ce crystal, the relationship between the photoluminescence (PL) light yield and excitation density was studied by Z scan experiments. The excitation threshold of the LYSO:Ce was obtained, which is about 2.3 J cm⁻³. Picosecond transient absorption of LYSO:Ce at 800 nm was obtained and used to analyze the dynamic process of carriers. The physical mechanism behind the nonlinearity was discussed and analyzed using the Förster dipole–dipole interaction model, and the interaction characteristic radius was obtained by fitting. This work can help us understand the nonlinearity phenomenon in scintillators and provide references for related radiation detection applications.

PL nonlinearity of LYSO:Ce studied by a UV laser at high excitation density, and the pump–probe absorption experiment used to look into the possible reasons for the nonlinearity effects occurring at high fluxes.     

An ink-jet printed dual-CD ratiometric fluorescent paper-based sensor for the visual detection of Cu2+

Copper ion (Cu²⁺) plays an important role in the human body because it is beneficial for metabolism. However, an excessive or slight amount of Cu²⁺ can cause various symptoms. Therefore, it is necessary for human health to realize the trace and visual detection of Cu²⁺. Referring to traditional fluorescence test papers, the qualitative and semi-quantitative detection of Cu²⁺ could be realized by a dual-carbon dots (CDs) ratiometric fluorescent paper-based sensor with the advantages of environmental protection, portability and low cost. In this paper, the inkjet-printed test paper with the best mixing ratio of the two CDs has been researched to maximize the spectral energy transfer of ion detection (maximum color gamut expansion). Among them, the preparation method of b-CDs has been improved, increasing the photoluminescence quantum yield (PLQY) to 88.9%. The sensitivity detection limit of the double emission ratio sensor was 0.15 nM in solution, and the human eye can distinguish at least 3 μmol L⁻¹ Cu²⁺ in the paper-based sensor. Compared with the traditional single-emission sensor, the human eye was more sensitive to the color change of the emission ratio sensor. The results indicate that we not only realized the micro detection of Cu²⁺ with convenient methods, but also provided a promising strategy for the visual detection of Cu²⁺.

A fluorescent test paper sensor for qualitative and semi-quantitative detection of Cu²⁺ is designed based on high photoluminescence quantum yield (PLQY) carbon dots (CDs).     

Metal-free catalytic hydrocarboxylation of hexafluorobut-2-yne

An efficient method for stereoselective synthesis of trifluorinated enol esters catalyzed by base was introduced. The DFT calculations and experimental results both supported the nucleophilic addition process. The protocol featured mild reaction conditions and showed a wide functional group tolerance. The one-pot simultaneous etherification and esterification of the salicylic acids further demonstrated the prospective synthetic application.

An efficient method for stereoselective synthesis of trifluorinated enol esters catalyzed by base was introduced.     

Nickel hydroxide as a non-noble metal co-catalyst decorated on Cd0.5Zn0.5S solid solution for enhanced hydrogen evolution

The study of non-noble metal photocatalysts provides practical significance for hydrogen evolution applications. Herein, new Cd_0.5Zn_0.5S/Ni(OH)₂ catalysts were fabricated through simple hydrothermal and precipitation methods. The photocatalytic performance of the Cd_0.5Zn_0.5S/Ni(OH)₂ composites under visible light was significantly improved, which was attributed to the wider visible light absorption range and less recombination of electron–hole pairs. The composite with a Ni(OH)₂ content of 10% showed the best hydrogen evolution rate of 46.6 mmol g⁻¹ h⁻¹, which was almost 9 times higher than that of pristine Cd_0.5Zn_0.5S. The severe photo-corrosion of Cd_0.5Zn_0.5S was greatly improved, and the Cd_0.5Zn_0.5S/Ni(OH)₂ composite exhibited a very high hydrogen evolution rate after three repeated tests. The excellent photocatalytic performance was due to the non-noble metal Ni(OH)₂ co-catalyst. The excited electrons were transferred to the co-catalyst, which reduced electron–hole recombination. Moreover, the co-catalyst offered more sites for photocatalytic reactions. This study researched the mechanism of a co-catalyst composite, providing new possibilities for non-noble metal photocatalysts.

This study researched the mechanism of a co-catalyst composite, providing new possibilities for non-noble metal photocatalysts.     

Facile fabrication of ion-imprinted Fe3O4/carboxymethyl cellulose magnetic biosorbent: removal and recovery properties for trivalent La ions

An Fe₃O₄/carboxymethyl cellulose (Fe₃O₄/CMC) magnetic biosorbent was prepared using the ion-imprinting technology, where La(iii) was used as the template ion. The morphology and structure of Fe₃O₄/CMC were characterized by SEM, FTIR and XRD. It is found that nano Fe₃O₄ with inverse spinel structure can distribute in CMC and endow the composite with good magnetic properties. The adsorption performance such as adsorption capacity, influence of pH and initial concentration were fully explored. The prepared Fe₃O₄/CMC is revealed to have good adsorption properties with Q_max of 61.5 mg g⁻¹, in line with the pseudo-second-order kinetic model. When handling the multi-ion coexistence solution of Cu(ii), Ni(ii) and Cd(ii), Fe₃O₄/CMC shows high selective adsorption for La(iii). Meanwhile, cycling experiments find that the adsorption capacity is only slightly reduced (less than 5%) after 5-time reuse. Good adsorption properties, high selectivity and easy recovery give the newly-synthesized Fe₃O₄/CMC biosorbent broad application potential in the treatment of La(iii)-containing wastewater.

An Fe₃O₄/carboxymethyl cellulose magnetic biosorbent was prepared by ion-imprinting technology, showing good adsorption and selectivity properties for La(iii) with a high recovery efficiency.     

A comparative study on the coordination of diglycolamide isomers with Nd(iii): extraction,third phase formation,structure, and computational studies

A novel asymmetric diglycolamide N,N-dimethyl-N′,N′-dioctyl diglycolamide (L^II) was synthesized. The Nd(iii) extraction behavior from HNO₃ and loading capability of the solution of L^II in 40/60 (v/v)% n-octanol/kerosene were studied. Analyses by the slope method, ESI-MS, and FT-IR indicated that, similar to the previously studied isomer ligand N,N′-dimethyl-N,N′-dioctyl diglycolamide (L^I), 1 : 3 Nd(iii)/L^II complexes formed. Under the same experimental conditions, the distribution ratio and limiting organic concentration of L^II towards Nd(iii) were smaller than those of L^I, but the critical aqueous concentration of L^II was larger, which implies that L^II exhibited poorer extraction and loading capabilities towards Nd(iii) than L^I, and L^II has a tendency to be less likely to form the third phase. The quasi-relativistic density functional theory (DFT) calculation was performed to provide some explanations for the differences in their extraction behaviors. The electrostatic potential of the ligands indicated that the electron-donating ability of the amide O atoms in L^II displayed certain differences compared with L^I. This inhomogeneity in L^II affected the interaction between L^II and Nd(iii), as supported by QTAIM and bonding nature analysis, and it seemed to reflect in the extraction performance towards Nd(iii).

The inhomogeneous interactions of M–O_amide in the L^II ligand result in differences between the metal-ion extraction performances of two isomeric ligands.     

Direct oxidation of N-ynylsulfonamides into N-sulfonyloxoacetamides with DMSO as a nucleophilic oxidant

N-Arylethynylsulfonamides are oxidized into N-sulfonyl-2-aryloxoacetamides directly and efficiently with dimethyl sulfoxide (DMSO) as both an oxidant and solvent with microwave assistance. DFT calculations indicate that DMSO nucleophilically attacks the ethylic triple bond and transfers its oxygen atom to the triple bond to form zwitterionic anionic N-sulfonyliminiums to trigger the reaction. Then it nucleophilically attacks the generated iminium intermediates to accomplish the oxidation via the second oxygen atom transfer. The current method provides a straightforward and efficient strategy to transform various N-arylethynylsulfonamides into N-sulfonyl-2-aryloxoacetamides, sulfonyl oxoacetimides, without any other electrophilic activators or oxidants.

Microwave-assisted direct oxidation of N-arylethynylsulfonamides with DMSO as a nucleophilic oxidant and solvent affords N-sulfonyl-2-aryloxoacetamides without any other additional electrophilic activators or oxidants.