HPLC法测定新疆鼠尾草三萜有效部位中熊果酸的含量

目的:建立新疆鼠尾草以三萜为有效部位的熊果酸含量的高效液相色谱检测方法。方法:采用高效液相色谱法(HPLC法)检测浸膏中熊果酸的含量,色谱柱为Waters Symmetry C18柱(4.6mm×250mm,5μm),流动相为甲醇—水—冰乙酸—三乙胺(85:15:0.03:0.06):甲醇=70:30,流速0.8ml/min,检测波长210nm,柱温30℃。结果:HPLC法测得熊果酸的线性范围为Y=447684X-7680(r=0.9999),平均回收率为98.84%,RSD=1.69%(n=6)。结论:HPLC法测定熊果酸含量,操作简便,灵敏度高,重现性好,可为新疆鼠尾草以三萜为有效部位的质量控制提供一定的依据。     

新疆鼠尾草水溶性有效部位的筛选研究

目的:测定新疆鼠尾草水溶性各部位丹酚酸类的含量,寻找有效部位。方法:采用UV分光光度法,分别对各部位丹酚酸类进行含量测定和方法学研究。结果:新疆鼠尾草地上部分80%甲醇提取物经大孔树脂柱分离的10%EtOH-H2O部分中丹酚酸类的含量为53.144%,为有效部位。结论:UV分光光度法操作简便,结果准确,便于推广,为新疆鼠尾草水溶性有效部位的筛选提供了科学依据。     

Cancer survivors. Work related issues.

New and more effective treatments for cancer have resulted in individuals living longer with a better quality of life. Many more survivors are employed in the workplace. Cancer is no longer only an issue for survivors and their families; it has become an issue for the employer and the workplace. This article describes survey results of 4,364 long term cancer survivors in which they were asked to respond to items describing their ability to work, job discrimination, and quality of life. Thirty-five percent of survivors were working at the time they completed the survey, and 8.5% considered themselves unable to work. This research has shown that age, gender, ethnic group, and cancer type affected the working status of the survivors. Of survivors continuing to work, 7.3% indicated they had experienced job discrimination. The results indicate most cancer survivors do not perceive employment related problems, and are readily assimilated into the work force. Job discrimination and the ability to work is a quality of life issue.     

Elements in muscle measured in vivo and in vitro with X-ray spectrometry

Calcium, iron, copper, and zinc concentrations in muscle were measured in vivo by x-ray spectrometry (XRS). The undersurface of the tongue was examined in cardiomyopathic and in normal hamsters. Values were compared to in-vitro analyses of various muscles from the same groups of animals using XRS and chemical analysis. Blood tests as well as histologic and histometric examinations were also performed. The correlated results show that XRS is a relatively sensitive and practical method for measuring chemical elements in muscle, and that it could be developed into a useful clinical test in certain neuromuscular and myocardial diseases. An interesting incidental finding was that, though all the examined muscles of myopathic animals had pathologic changes, only the tongue and myocardium, which are composed exclusively of red fibers, showed excessive calcium accumulation. This suggests either that the basic genetic aberration is not directly related to the oxidative metabolism, or that white muscles have a more efficient system for dealing with calcium overload.     

Metastatic tumor of spermatic cord with elevation of serum human chorionic gonadotropin beta-subunit

A 62-year-old man was presented with a firm mass in right scrotum. Serum LDH and AFP were within normal range, but hCG-beta was elevated (2.3 ng/ml). Under the diagnosis of right testicular tumor, he underwent right radical orchiectomy. The specimen was a spermatic cord tumor with poorly differentiated adenocarcinoma. hCG-beta was still elevated postoperatively and gastric fiber revealed adenocarcinoma of the stomach. Histochemical staining for hCG-beta was positive in both tumor of the spermatic cord and stomach. Finally the tumor was diagnosed as metastatic tumor of spermatic cord from gastric cancer, causing the elevation of hCG-beta.     

Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin

We present two cases of infertile male patients with oligoasthenozoospermia who were receiving anti-epilepsy medication. Complete reversal of the spermatic dysfunction followed by a successful conception was achieved after discontinuation of sodium valproate, suggesting that the drug was responsible for spermatic dysfunction in these individuals.     

Reanalysis of Weight Changes in Behavior Modification and Nutrition Education for Childhood Obesity

Changes in percentage overweight for children who were providedbehavior modification were 1.7 times as great as those providednutrition education during treatment, and 2.7 times as greatby the end of follow-up. The superiority of behavior modificationto nutrition education was shown for comparisons of means inthree separate analyses. However, examination of the three studieswhich have studied parent and child weight changes when bothare offered treatment, in general, show that differential effectsof treatments are observed more reliably for the parents thanthe children. Possible reasons for these results are discussed.     

Language development in preschool-age children adopted from China.

This study examined the language development of 55 preschool-age children adopted from China who had resided in their permanent homes for approximately 2 years or longer. Slightly over 5% of the children scored below average on 2 or more measures from a battery of standardized speech-language tests normed on monolingual English speakers. However, the vast majority scored within or well above the average range on 2 or more measures. Contrary to other reports on the language development of internationally adopted children, the results suggest that "second first language" acquisition proceeds rapidly in the majority of preschool-age children adopted as infants and toddlers. For the children in the sample who scored below average, results indicated that they were among the children who had been exposed to English for the least amount of time. The results of this study demonstrate both the robustness of the language system in the majority of adopted children from China as well as slower growth in a small subset of lower performers in the 1st years after adoption.