Characteristics of the Bibliometric Indexes of Chinese Core Journals on Environmental and Occupational Medicine

This paper investigated the current characteristics and changing trends of major journals on Chinese environmental and occupational medicine in order to promote the development of these journals. This study focused on the seven core journals in the area of environmental and occupational medicine listed on the Chinese Scientific and Technical Journal Citation Reports (2008 version). These journals were China Occupational Medicine, Chinese Journal of Industrial Hygiene and Occupational Diseases, Chinese Journal of Industrial Medicine, Industrial Health and Occupational Diseases, Journal of Environment and Health, Journal of Environmental and Occupational Medicine, Occupation and Health. Various observations were based on data from www. cnki.net and Chinese Scientific and Technical Journal Citation Reports (2008 version), including cover of the journal, issue period, exposure to the internet, level of open source, impact factor, cited half-life, web immediacy index and rate of downloads per year. The outcomes showed that in appearance, the overall characteristics were continuous improvement of the covers, issue period, and moving toward the internet. In terms of contents, all factors had been improving.Nevertheless the level of influence was not very stable. The use of internet and the level of resource openness still have a long way to go to meet the international standard. There is still a huge gap for improvement. The contents and the appearance both need to be improved to serve the ever developing environmental and occupational medicine career.     

弥漫性大B细胞淋巴瘤中CD40L的表达及意义

目的探讨弥漫性大B细胞淋巴瘤（DLBCL）组织中CD40L表达与DLBCL预后间的关系及意义。方法免疫组织化学法检测27例弥漫性大B细胞淋巴瘤、20例淋巴结反应性增生组织中CD40L的表达。结果（1）DLBCL中CD40L过度阳性率（25．93％）显著低于淋巴结反应性增生（63．64％），P〈0．05。（2）CD40L在Ⅲ、Ⅳ期DLBCL过度阳性率（14．29％）低于Ⅰ、Ⅱ期（38．46％），P〈0．05。CD40L过度阳性率在有结外浸润DLBCL（11．76％）低于无有结外浸润DLBCL（40％），P〈0．05。（3）DLBCL患者CD40L的过度阳性率与远处转移、临床分期均显著相关，P〈0．05。结论（1）CD40L过度阳性率与结外器官浸润及临床分期密切相关，其可能作为判断DLBCL侵袭性及预后的指标。（2）DLBCL中CD40L表达的减少可能是影响其发病的因素之一。     

中鼻道及其周围结构的解剖学观测

目的　探讨临床上经上颌窦口进入上颌窦诊疗的途径。方法　在 40例成人尸体颅矢状切面上 ,对中鼻道、半月裂孔、上颌窦口及其周围结构进行解剖学观测及上颌窦口的探针插入试验。结果　中鼻道、半月裂孔的长度分别为5 6.3 6± 2 .5 8mm、2 1.46± 1.79mm ;40例中 ,2 8侧 (70 .0 0 % )的上颌窦口位于半月裂孔的中 1/3部 ;12侧 (3 0 .0 0 % )的上颌窦口位于半月裂孔的后 1/3部。上颌窦口的形态不一。上颌窦口的前后径为 3 .14± 0 .47mm。上颌窦口距鼻腔底部、鼻小柱的距离分别为 3 0 .41± 2 .85mm、49.5 2± 2 .3 7mm。鼻小柱到上颌窦口与到鼻腔基底面连线的夹角为 40 .2± 3 .7°。 3 7侧 (92 .5 0 % )的上颌窦口能用直径≤ 2 .5mm的探针穿过。结论　经上颌窦自然开口行上颌窦口穿刺是安全、简便和有效的一种诊治方法。     

对耳轮过度前突畸形的整复

对耳轮过度前突为对耳轮的角度过锐，致使耳轮的位置相应后移，表现为与招风耳完全相反的畸形。畸形虽不十分明显，但影响美观。自１９９２年４月开始应用患侧耳廓软骨和耳后皮瓣对５例患者８只外耳进行治疗得到满意效果。认为文中所述方法是矫正对耳轮过度前突畸形的良好方法。     

二乙基二硫代氨基甲酸钠驱镍作用的实验研究

本文用大鼠研究了带-SH基的二乙基二硫代氨基甲酸钠(Dithiocarb,简称Na-DDC或称铜试剂)和不带-SH基的新螯合剂(H-73-10)的驱镍作用。结果表明,Na-DDC对羰基镍(Ni(CO)_4〕的驱镍作用明显优于H-73-10;与此相反,H-73-10对硝酸镍〔Ni(NO_3)_2〕染毒大鼠的驱镍作用却明显优于Na-DDC。     

检测胞浆抗原用于急性白血病免疫分型

目的:探讨胞浆抗原在急性白血病免疫分型中的临床意义。方法:用流式细胞仪检测42例初治急性白血病患者胞浆抗原CyCD_3,CyCD_(22),CyCD_(79a)和MPO。结果:T—ALL阳性胞浆抗原主要表达在CyCD_3,阳性率占88.9％。B—ALL阳性胞浆抗原主要表达在CyCD_(79a),AML主要表达CyMPO。结论:CyCD_3和CyCD_(79a),及MPO可分别作为T—ALL,B—ALL和AML系列特异性标志,对正确诊断白血病提供非常有价值的依据。     

Ethylene oxide does not extinguish the osteoinductive capacity of demineralized bone: A reappraisal in rats

We examined the influence of ethylene oxide (EO) and gamma irradiation on the osteoinductive capacity of demineralized bone. Demineralized bone powder prepared from Wistar rats was exposed to EO (55 °C or 40 °C) or gamma irradiation (25 KGy) or was preserved in ethanol. Sterilely-prepared bones served as controls. The powder was packed in a gelatin capsule and implanted for 6 weeks in muscles of 6-week-old female rats. Exposure of demineralized bone particles to EO 55 °C resulted in an almost complete loss of osteoinductivity. Irradiated bones lost about 40% of their osteoinductive capacity, while sterilization with EO at 40 °C resulted in only a slight alteration of the osteoinductivity, as assessed by the recovered weight ratio, calcium content, alkaline phosphatase activity measurements and histo-morphometry. Ethanol treatment had no influence on the new bone yield when compared to controls.

As EO exposure at 40 °C is a true sterilization procedure, it can be recommended in a clinical setting for its small effect on osteoinductive capacity as assessed experimentally in rats.     

防床垫污染保护罩使用效果的研究

目的 探讨防止病房床垫污染的有效方法，保持床垫干燥洁净，消除医院感染隐患。方法 选择病房使用中的床垫100张，随机分成实验组和对照组各50张，两组床垫经清洁、消毒后进行表面采样，送细菌培养，然后，实验组先铺保护罩再铺床单，对照组直接铺床单，比较两组在第3、7、14天的细菌菌落数。结果 实验组床垫干净污染轻、菌落数少，对照组床垫污染重、菌落数多；两组床垫在第3、7、14天的菌落总数及各采样点菌落数比较差异均有统计学意义（P〈0．01）。结论保护罩防渗阻菌性能良好，可保护床垫免受污染。     

南阳市1999～2001年新生儿破伤风疫情监测

目的 对南阳市3年的新生儿破伤风疫情监测结果进行分析，掌握该市新生儿破伤风发病概况，有针对地制订防治对策。方法 对3年的监测资料进行分析评价。结果 1999—2001年3年的发病率分别为0．09‰、0．07‰、0．04‰，发病县3年的年发病率均小于1‰。结论 开展各种形式的宣传活动，提倡住院分娩，推广消毒接生，对育龄妇女进行破伤风类毒素接种，从而有效降低其发病率。     

脉冲式电磁辐射对大鼠血脑屏障影响的量效关系

目的 研究脉冲式电磁辐射(EMR)对大鼠血脑屏障(BBB)影响的量效关系。方法 采用伊思蓝静脉注射，荧光显微镜下观察不同脉冲次数的EMR辐照对大鼠BBB开放的影响。结果 伊思蓝在EMR诱发的大鼠BBB开放局部呈现荧光斑；随着EMR脉冲次数(0～200次)的增加，荧光斑数量增加、面积增大；荧光斑在EMR组全脑的分布，以皮质、丘脑、下丘脑、小脑、尾壳核和延髓较多。结论 不同脉冲次数EMR诱发大鼠BBB开放程度不同，随脉冲次数增加，血管通透性增强，200次时达开放高峰，皮质区BBB开放最明显。