全文获取类型
收费全文 | 2417篇 |
免费 | 170篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 139篇 |
妇产科学 | 68篇 |
基础医学 | 365篇 |
口腔科学 | 74篇 |
临床医学 | 217篇 |
内科学 | 530篇 |
皮肤病学 | 51篇 |
神经病学 | 156篇 |
特种医学 | 64篇 |
外科学 | 271篇 |
综合类 | 28篇 |
一般理论 | 2篇 |
预防医学 | 144篇 |
眼科学 | 111篇 |
药学 | 152篇 |
中国医学 | 13篇 |
肿瘤学 | 200篇 |
出版年
2024年 | 4篇 |
2023年 | 50篇 |
2022年 | 79篇 |
2021年 | 141篇 |
2020年 | 91篇 |
2019年 | 118篇 |
2018年 | 142篇 |
2017年 | 111篇 |
2016年 | 105篇 |
2015年 | 80篇 |
2014年 | 119篇 |
2013年 | 164篇 |
2012年 | 227篇 |
2011年 | 197篇 |
2010年 | 138篇 |
2009年 | 80篇 |
2008年 | 149篇 |
2007年 | 135篇 |
2006年 | 113篇 |
2005年 | 83篇 |
2004年 | 97篇 |
2003年 | 69篇 |
2002年 | 59篇 |
2001年 | 6篇 |
2000年 | 7篇 |
1999年 | 5篇 |
1998年 | 9篇 |
1997年 | 5篇 |
1996年 | 4篇 |
1995年 | 6篇 |
1994年 | 4篇 |
1993年 | 2篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1976年 | 2篇 |
排序方式: 共有2605条查询结果,搜索用时 15 毫秒
31.
Desirée Gutiérrez-Marín Joaquin Escribano Ricardo Closa-Monasterolo Natalia Ferré Michelle Venables Priya Singh Jonathan C.K. Wells Judit Muñoz-Hernando Marta Zaragoza-Jordana Mariona Gispert-Llauradó Carmen Rubio-Torrents Mireia Alcázar Mercè Núñez-Roig Raquel Monné-Gelonch Albert Feliu Josep Basora Ana M. Alejos Veronica Luque 《Clinical nutrition (Edinburgh, Scotland)》2021,40(3):1102-1107
32.
33.
Preston L. Visser Priya Loess Elizabeth L. Jeglic Jameson K. Hirsch 《Stress and health》2013,29(1):82-88
Depression is a significant public health problem for young adults of college age, and negative life events exacerbate risk. Not all individuals who experience negative life events, however, report depressive symptoms, perhaps owing to protective characteristics. We examined one such characteristic, trait hope, a goal‐oriented construct, as a potential moderator of the association between negative life events and depressive symptoms in an ethnically diverse sample of 386 college students. In support of our hypotheses, negative life events were significantly associated with greater levels of depressive symptoms, and higher levels of hope attenuated this relationship, such that those with greater hope reported fewer depressive symptoms related to potentially traumatic events. The moderating effect of hope did not differ across ethnic groups. Our findings have implications for managing the sequelae of negative life events, including depression. Cognitive–behavioural interventions tailored to help young adults identify and attain important life goals might help to overcome psychopathology associated with life stress. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
34.
ABSTRACT: BACKGROUND: Introducing a new method into family planning programs requires careful attention to ensure it meets an actual need and has a positive effect on program goals. The Standard Days Method(R) is a fertility awareness-based method of family planning that is being introduced into family planning programs in countries around the world. It is different from other methods offered by programs, and may bring new couples into family planning, and increase contraceptive prevalence. The study assesses the effect on contraceptive use and prevalence of Introducing Standard Days Method into existing family planning services in whole regions of India, Peru, and Rwanda. METHODS: In collaboration with the Ministry of Health, health providers were given a contraceptive update on all methods, then trained in counseling on Standard Days Method. Efforts were made to promote demand in the context of informed choice. Routine monthly service statistics in control and intervention areas were used to assess the effect of Standard Days Method introduction at the clinic level; baseline and endline household-based surveys were undertaken to obtain results at the community level (n > 3400 women at endline). RESULTS: Demand for the method is evident in countries with different levels of contraceptive prevalence. The method attracts couples new to family planning, and introducing it into services may increase overall contraceptive prevalence. CONCLUSIONS: Introducing Standard Days Method into existing family planning has the potential of benefiting men and women in diverse settings and populations. This study illustrates the critical role of evidence in scaling up a health innovation. 相似文献
35.
36.
37.
38.
Priya Palta G. Page R. L. Piferi J. M. Gill M. J. Hayat A. B. Connolly S. L. Szanton 《Journal of urban health》2012,89(2):308-316
Hypertension affects a large proportion of urban African-American older adults. While there have been great strides in drug
development, many older adults do not have access to such medicines or do not take them. Mindfulness-based stress reduction
(MBSR) has been shown to decrease blood pressure in some populations. This has not been tested in low-income, urban African-American
older adults. Therefore, the primary purpose of this pilot study was to test the feasibility and acceptability of a mindfulness-based
program for low income, minority older adults provided in residence. The secondary purpose was to learn if the mindfulness-based
program produced differences in blood pressure between the intervention and control groups. Participants were at least 62 years
old and residents of a low-income senior residence. All participants were African-American, and one was male. Twenty participants
were randomized to the mindfulness-based intervention or a social support control group of the same duration and dose. Blood
pressure was measured with the Omron automatic blood pressure machine at baseline and at the end of the 8-week intervention.
A multivariate regression analysis was performed on the difference in scores between baseline and post-intervention blood
pressure measurements, controlling for age, education, smoking status, and anti-hypertensive medication use. Effect sizes
were calculated to quantify the magnitude of the relationship between participation in the mindfulness-based intervention
and the outcome variable, blood pressure. Attendance remained >80% in all 8 weeks of both the intervention and the control
groups. The average systolic blood pressure decreased for both groups post-intervention. Individuals in the intervention group
exhibited a 21.92-mmHg lower systolic blood pressure compared to the social support control group post-intervention and this
value was statistically significant (p = 0.020). The average diastolic blood pressure decreased in the intervention group post-intervention, but increased in the
social support group. Individuals in the intervention group exhibited a 16.70-mmHg lower diastolic blood pressure compared
to the social support group post-intervention, and this value was statistically significant (p = 0.003). Older adults are at a time in life when a reflective, stationary intervention, delivered in residence, could be
an appealing mechanism to improve blood pressure. Given our preliminary results, larger trials in this hypertensive study
population are warranted. 相似文献
39.
40.
Duggal P Haque R Roy S Mondal D Sack RB Farr BM Beaty TH Petri WA 《The Journal of infectious diseases》2004,189(3):520-526
BACKGROUND: The association of antibody responses with both innate and acquired immunity to amebiasis indicate that CD4+ T cells play a role in protection against Entamoeba histolytica infection. To test this hypothesis, we compared the genotype frequencies of human leukocyte antigen (HLA) class II alleles in a cohort of Bangladeshi children intensively monitored for E. histolytica infection for a 3-year period. METHODS: Using logistic regression, we calculated the odds of disease by genotype and by haplotype. RESULTS: The DQB1*0601 heterozygous and homozygous genotypes were found in 55% of E. histolytica-negative children but in only 34% of E. histolytica-positive children (overall odds ratio, 2.39; 95% confidence interval [CI], 1.26-4.54). Children who were heterozygous for the DQB1*0601/DRB1*1501 haplotype were 10.1 times (95% CI, 2.02-50.6) more likely to be both E. histolytica negative and serum anti-lectin immunoglobulin G negative at baseline. Other DQB1 and DRB1 alleles (DQB1*0202, DQB1*0301, and DRB1*0701) were not associated with any of the clinical outcomes related to amebiasis. CONCLUSION: A potential protective association was observed with the HLA class II allele DQB1*0601 and the heterozygous haplotype DQB1*0601/DRB1*1501. This association may explain why amebiasis does not occur in some children who are exposed to the parasite and implicates HLA class II-restricted immune responses in protection against E. histolytica infection. 相似文献