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Sidney Zisook M.D. Emmanuelle Corruble M.D. Ph.D. Naihua Duan Ph.D. Alana Iglewicz M.D. Elie G. Karam M.D. Nicole Lanouette M.D. Barry Lebowitz Ph.D. Ronald Pies M.D. Charles Reynolds M.D. Kathryn Seay B.S. M. Katherine Shear M.D. Naomi Simon M.D. Ilanit Tal Young M.D. 《Depression and anxiety》2012,29(7):665-665
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A R Beeber M D Kline R W Pies J M Manring 《The Journal of nervous and mental disease》1984,172(5):301-303
There is considerable disagreement about the relationship between borderline personality disorder and the affective disorders. The authors report the results of a study of the relationship between dexamethasone suppression and depressive subtype in hospitalized depressed borderline patients. Twenty-three patients met research criteria for unipolar major depressive episode without psychosis of at least moderate severity. Thirteen patients also met criteria for borderline personality disorder. Dexamethasone suppression test (DST) results showed no significant correlation with either melancholia or borderline personality disorder alone. However, of the 13 borderlines, eight failed to suppress and six of those eight were not melancholic. The authors conclude that abnormal response to dexamethasone in nonmelancholic borderlines casts some doubt on the specificity of the DST for melancholia. 相似文献
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Pies R 《Innovations in clinical neuroscience》2011,8(2):23-27
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition appears likely to eliminate the diagnosis of narcissistic personality disorder. There are significant problems with the discriminant validity of the current narcissistic personality disorder critiera set; furthermore, the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition's narrow focus on "grandiosity" probably contributes to the wide disparity between low narcissistic personality disorder prevalence rates in epidemiological studies and high rates of narcissistic personality disorder in clinical practice. Nevertheless, the best course of action may be to refine the narcissistic personality disorder criteria, followed by careful field testing and a search for biomarkers, rather than wholesale elimination of the narcissistic personality disorder category. The construct of "malignant narcissism" is also worthy of more intense empirical investigation. 相似文献