全文获取类型
收费全文 | 5492篇 |
免费 | 299篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 42篇 |
儿科学 | 326篇 |
妇产科学 | 82篇 |
基础医学 | 661篇 |
口腔科学 | 84篇 |
临床医学 | 402篇 |
内科学 | 1194篇 |
皮肤病学 | 62篇 |
神经病学 | 430篇 |
特种医学 | 106篇 |
外科学 | 758篇 |
综合类 | 144篇 |
一般理论 | 1篇 |
预防医学 | 304篇 |
眼科学 | 195篇 |
药学 | 608篇 |
中国医学 | 78篇 |
肿瘤学 | 338篇 |
出版年
2023年 | 39篇 |
2022年 | 70篇 |
2021年 | 208篇 |
2020年 | 91篇 |
2019年 | 135篇 |
2018年 | 181篇 |
2017年 | 126篇 |
2016年 | 139篇 |
2015年 | 165篇 |
2014年 | 234篇 |
2013年 | 320篇 |
2012年 | 418篇 |
2011年 | 445篇 |
2010年 | 248篇 |
2009年 | 209篇 |
2008年 | 317篇 |
2007年 | 302篇 |
2006年 | 249篇 |
2005年 | 252篇 |
2004年 | 194篇 |
2003年 | 176篇 |
2002年 | 182篇 |
2001年 | 83篇 |
2000年 | 80篇 |
1999年 | 82篇 |
1998年 | 54篇 |
1997年 | 27篇 |
1996年 | 35篇 |
1995年 | 27篇 |
1993年 | 26篇 |
1992年 | 40篇 |
1991年 | 56篇 |
1990年 | 56篇 |
1989年 | 42篇 |
1988年 | 34篇 |
1987年 | 40篇 |
1986年 | 25篇 |
1985年 | 47篇 |
1984年 | 31篇 |
1983年 | 27篇 |
1982年 | 23篇 |
1981年 | 16篇 |
1980年 | 16篇 |
1979年 | 20篇 |
1978年 | 23篇 |
1977年 | 19篇 |
1974年 | 15篇 |
1973年 | 23篇 |
1971年 | 17篇 |
1969年 | 18篇 |
排序方式: 共有5815条查询结果,搜索用时 140 毫秒
81.
Bal Kishan Gupta Kailash Chandra Nayak Sunil Kumar Surendra Kumar Anjli Gupta Parul Prakash 《急性病杂志》2012,1(2):100-106
ObjectiveTo report a comparative clinical and histopathological study on oliguric and non-oliguric acute renal failure (ARF) in malaria.Method311 consecutive cases of malaria out of which 74 (23.79%) had ARF as per WHO criteria were conducted. Mean age was 32.58 (range 15–60 years) and male: female was 2:1.ResultMost of the cases developed ARF within 10 d of onset. 18 cases (11 falciparum, 2 mixed, 5 vivax) presented with oliguric and 56 (41 falciparum, 6 mixed, 9 vivax) with non-oliguric renal failure. Associated major manifestations were jaundice (75.68%), cerebral malaria (41.89%), bleeding manifestations (32.43%), severe anemia (27.03%), hypotension (25.68%), multi-organ failure (18.92%), severe thrombocytopenia (12.16%), and ARDS (8.11%). Kidney biopsy (n=20) showed acute tubular necrosis (n=7), Mesangioproliferative glomerulonephritis (n=4) or both (n=9). Hemodialysis was done in 8 cases of oliguric renal failure out of which 4 survived (average no. of session 2.9).ConclusionMost of the cases recovered within 3 weeks. Total mortality was 28.38% (n=21) and mortality was more in oliguric renal failure (72.22%) as compare to non-oliguric renal failure (14.29%). 相似文献
82.
83.
84.
Atin Jaiswal Naiman Deepak Kachchhapt Rupak Chaterjee Yashwant Singh Tanwar Masood Habib Satya Prakash Singh 《中华创伤杂志(英文版)》2013,16(6):379-381
Fractures of the proximal humerus are uncommon in young patients.Although bilateral fracture of proximal humerus itself is rare,association with epilepsy and electrocution is frequent.Only one case of traumatic bilateral proximal humerus fracture has been reported in the literature.We report a rare case of bilateral traumatic displaced proximal humerus fractures in a 40 years old male patient,which was treated by means of open reduction and internal fixation with proximal humerus locked pates on both sides and obtained a good functional outcome. 相似文献
85.
86.
87.
The utilization of impedance technology has enhanced our understanding and assessment of esophageal dysmotility. Esophageal high-resolution manometry (HRM) catheters incorporated with multiple impedance electrodes help assess esophageal bolus transit, and the combination is termed high-resolution impedance manometry (HRIM). Novel metrics have been developed with HRIM—including esophageal impedance integral ratio, bolus flow time, nadir impedance pressure, and impedance bolus height—that augments the assessment of esophageal bolus transit. Automated impedance-manometry (AIM) analysis has enhanced understanding of the relationship between bolus transit and pressure phenomena. Impedance-based metrics have improved understanding of the dynamics of esophageal bolus transit into four distinct phases, may correlate with symptomatic burden, and can assess the adequacy of therapy for achalasia. An extension of the use of impedance involves impedance planimetry and the functional lumen imaging probe (FLIP), which assesses esophageal biophysical properties and distensibility, and could detect patterns of esophageal contractility not seen on HRM. Impedance technology, therefore, has a significant impact on esophageal function testing in the present day. 相似文献
88.
89.
Shraddha Rani Modapathi Anusha Rohit Vankadari Aditya Varsha Prakash Shetty Akshatha Kotian Praveen Rai Indrani Karunasagar Vijaya Kumar Deekshit 《Indian journal of medical microbiology》2022,40(1):74-80
PurposeBurkholderia is a Gram-negative opportunistic bacterium capable of causing severe nosocomial infections. The aim of this study was to characterize Burkholderia cepacia complex and to compare different molecular methods used in its characterization.MethodsIn this study, 45 isolates of Burkholderia cepacia complex (Bcc) isolated from clinical cases were subjected to RAPD (Random amplified polymorphic DNA), recA-RFLP (Restriction fragment length polymorphism), 16SrDNA-RFLP, whole-cell protein analysis, recA DNA sequencing and biofilm assay.ResultsOf the 45 isolates tested, 97.7% were sensitive to ceftazidime, 82.2% were sensitive to Cotrimoxazole, 73.3% were sensitive to meropenem, 55.5% were sensitive to minocycline and 42.2% were sensitive to levofloxacin. Majority of the isolates harbored all the tested virulence genes except bpeA and cblA. The RAPD generated 11 groups (R1-R11), recA-RFLP 10 groups (A1-A10), 16SrRNA-RFLP 5 groups (S1–S5) and SDS-PAGE (Sodium Dodecyl Sulphate-Polyacrylamide gel electrophoresis) whole cell protein analysis revealed 12 groups (C1–C12). recA sequencing revealed that most of the isolates belonging to the genomovar III Burkholderia cenocepacia. Though all the methods are found to be efficient in differentiating Burkholderia spp., recA-RFLP was highly discriminatory at 96% similarity value. The study also identified a new strain Burkholderia pseudomultivorans for the first time in the country. Further, recA sequencing could identify the strains to species level. Majority of the multidrug-resistant strains also showed moderate to strong biofilm-forming ability, which further contributes to the virulence characteristics of the pathogens.ConclusionsThe study highlights the importance of combination of molecular methods to characterize Burkholderia cepacia complex. Molecular typing of these human pathogens yields important information for the clinicians in order to initiate the most appropriate therapy in the case of severe infections and to implement preventive measures for the effective control of transmission of Burkholderia spp. 相似文献
90.
Yuli Y. Kim Lisa D. Levine Sara L. Partington Prakash A. Patel Emily Ruckdeschel Suneeta Senapati Clarisa R. Gracia 《Journal of assisted reproduction and genetics》2020,37(12):3017
PurposePatients with single ventricle anatomy palliated with Fontan operation are at risk for thromboembolism, arrhythmia, and heart failure rendering pregnancy high risk or even contraindicated. Infertility and high rates of first trimester miscarriage are not uncommon. In vitro fertilization (IVF) with or without gestational surrogacy can be an option, but poses risks during ovarian stimulation, oocyte retrieval, and the post-procedural period. We present six cases of women with complex congenital heart disease status post Fontan operation who underwent successful IVF.MethodsCase series from a single-center tertiary care setting.ResultsIndications for referral were cardiac or fertility concerns for pregnancy of the congenital cardiologist. One woman had mild volume overload after oocyte retrieval requiring furosemide and one experienced post-operative colitis. There were no thrombotic complications.ConclusionsA multidisciplinary team-based approach can result in successful oocyte retrieval and IVF in women with complex congenital heart disease and Fontan physiology. 相似文献