全文获取类型
收费全文 | 39700篇 |
免费 | 2511篇 |
国内免费 | 265篇 |
专业分类
耳鼻咽喉 | 474篇 |
儿科学 | 1193篇 |
妇产科学 | 1205篇 |
基础医学 | 4268篇 |
口腔科学 | 1141篇 |
临床医学 | 3192篇 |
内科学 | 8182篇 |
皮肤病学 | 844篇 |
神经病学 | 1910篇 |
特种医学 | 1366篇 |
外国民族医学 | 18篇 |
外科学 | 7081篇 |
综合类 | 984篇 |
现状与发展 | 2篇 |
一般理论 | 31篇 |
预防医学 | 3056篇 |
眼科学 | 1172篇 |
药学 | 3602篇 |
中国医学 | 281篇 |
肿瘤学 | 2474篇 |
出版年
2023年 | 452篇 |
2022年 | 879篇 |
2021年 | 2272篇 |
2020年 | 1203篇 |
2019年 | 1542篇 |
2018年 | 2041篇 |
2017年 | 1258篇 |
2016年 | 1275篇 |
2015年 | 1403篇 |
2014年 | 1835篇 |
2013年 | 2211篇 |
2012年 | 3163篇 |
2011年 | 3310篇 |
2010年 | 1794篇 |
2009年 | 1395篇 |
2008年 | 2009篇 |
2007年 | 2115篇 |
2006年 | 1896篇 |
2005年 | 1724篇 |
2004年 | 1553篇 |
2003年 | 1379篇 |
2002年 | 1264篇 |
2001年 | 461篇 |
2000年 | 424篇 |
1999年 | 381篇 |
1998年 | 227篇 |
1997年 | 186篇 |
1996年 | 169篇 |
1995年 | 164篇 |
1994年 | 126篇 |
1993年 | 103篇 |
1992年 | 177篇 |
1991年 | 174篇 |
1990年 | 168篇 |
1989年 | 146篇 |
1988年 | 142篇 |
1987年 | 136篇 |
1986年 | 135篇 |
1985年 | 121篇 |
1984年 | 107篇 |
1983年 | 119篇 |
1982年 | 68篇 |
1981年 | 67篇 |
1980年 | 51篇 |
1979年 | 87篇 |
1978年 | 59篇 |
1977年 | 64篇 |
1976年 | 58篇 |
1975年 | 52篇 |
1974年 | 50篇 |
排序方式: 共有10000条查询结果,搜索用时 375 毫秒
951.
952.
953.
954.
955.
956.
957.
ST Hornby FD McDermott M Coleman Z Ahmed J Bunni D Bunting M Elshaer V Evans A Kimble M Kostalas G Page J Singh L Szczebiot S Wienand-Barnett A Wilkins O Williams P Newell Severn Peninsula Audit Research Collaborative 《Annals of the Royal College of Surgeons of England》2015,97(2):115-119
Background
Laparoscopic hernia repair is used widely for the repair of incisional hernias. Few case studies have focussed on purely ‘incisional’ hernias. This multicentre series represents a collaborative effort and employed statistical analyses to provide insight into the factors predisposing to recurrence of incisional hernia after laparoscopic repair. A specific hypothesis (ie, laterality of hernias as well as proximity to the xyphoid process and pubic symphysis predisposes to recurrence) was also tested.Methods
This was a retrospective study of all laparoscopic incisional hernias undertaken in six centres from 1 January 2004 to 31 December 2010. It comprised a comprehensive review of case notes and a follow-up using a structured telephone questionnaire. Patient demographics, previous medical/surgical history, surgical procedure, postoperative recovery, and perceived effect on quality of life were recorded. Repairs undertaken for primary ventral hernias were excluded. A logistic regression analysis was then fitted with recurrence as the primary outcome.Results
A total of 186 cases (91 females) were identified. Median follow-up was 42 months. Telephone interviews were answered by 115/186 (62%) of subjects. Logistic regression analyses suggested that only female sex (odds ratio (OR) 3.53; 95% confidence interval (CI) 1.39–8.97) and diabetes mellitus (3.54; 1–12.56) significantly increased the risk of recurrence. Position of the defect had no statistical effect.Conclusions
These data suggest an increased risk of recurrence after laparoscopic incisional hernia repair in females and subjects with diabetes mellitus. These data will help inform surgeons and patients when considering laparoscopic management of incisional hernias. We recommend a centrally hosted, prospectively maintained national/international database to carry out additional research. 相似文献958.
959.
Molecular signalling of a novel curcumin derivative versus Tadalafil in erectile dysfunction
下载免费PDF全文
![点击此处可从《Andrologia》网站下载免费的PDF全文](/ch/ext_images/free.gif)
M. T. Abdel Aziz A. M. Rezq H. M. Atta H. Fouad A. M. Zaahkouk H. H. Ahmed D. Sabry H. M. Yehia 《Andrologia》2015,47(6):616-625
The efficacy of a novel curcumin derivative (NCD) versus tadalafil in erectile signalling was assessed. Ten control male rats and 50 diabetic male rats were used and divided into the following: diabetic (DM), curcumin (CURC), NCD, tadalafil and NCD combined with tadalafil rat groups. Cavernous tissue gene expression of heme oxygenase‐1 (HO‐1), Nrf2, NF‐B and p38, enzyme activities of heme oxygenase (HO) and nitric oxide synthase (NOS), cGMP and intracavernosal pressure (ICP)/mean arterial pressure (MAP) were assessed. Results showed that 12 weeks after induction of diabetes, erectile dysfunction (ED) was confirmed by the significant decrease in ICP/MAP, a significant decrease in cGMP, NOS, HO enzyme activities, a significant decrease in HO‐1 gene and a significant increase in NF‐?β, p38 genes. Administration of all therapeutic interventions led to a significant increase in ICP/MAP, cGMP levels, a significant increase in HO‐1 and NOS enzymes, a significant increase in HO‐1, and Nrf2 gene expression, and a significant decrease in NF‐?β, p38 gene expression. NCD or its combination with tadalafil showed significant superiority and more prolonged duration of action. In conclusion, a tendency was observed that CURC and NCD have high efficacy and more prolonged duration of action in enhancing erectile function. 相似文献