全文获取类型
收费全文 | 2885322篇 |
免费 | 216724篇 |
国内免费 | 29921篇 |
专业分类
耳鼻咽喉 | 37062篇 |
儿科学 | 88350篇 |
妇产科学 | 76124篇 |
基础医学 | 399899篇 |
口腔科学 | 74781篇 |
临床医学 | 277780篇 |
内科学 | 560325篇 |
皮肤病学 | 65184篇 |
神经病学 | 230290篇 |
特种医学 | 111212篇 |
外国民族医学 | 948篇 |
外科学 | 416760篇 |
综合类 | 99334篇 |
现状与发展 | 81篇 |
一般理论 | 983篇 |
预防医学 | 214737篇 |
眼科学 | 65762篇 |
药学 | 219034篇 |
342篇 | |
中国医学 | 22581篇 |
肿瘤学 | 170398篇 |
出版年
2022年 | 21219篇 |
2021年 | 35725篇 |
2020年 | 24265篇 |
2019年 | 31004篇 |
2018年 | 40150篇 |
2017年 | 32080篇 |
2016年 | 35061篇 |
2015年 | 43194篇 |
2014年 | 57468篇 |
2013年 | 74928篇 |
2012年 | 101684篇 |
2011年 | 108894篇 |
2010年 | 66150篇 |
2009年 | 60773篇 |
2008年 | 94965篇 |
2007年 | 99714篇 |
2006年 | 101574篇 |
2005年 | 97589篇 |
2004年 | 88593篇 |
2003年 | 85141篇 |
2002年 | 81167篇 |
2001年 | 134410篇 |
2000年 | 138237篇 |
1999年 | 118427篇 |
1998年 | 36417篇 |
1997年 | 33175篇 |
1996年 | 32359篇 |
1995年 | 31157篇 |
1994年 | 28140篇 |
1993年 | 25380篇 |
1992年 | 87526篇 |
1991年 | 83575篇 |
1990年 | 80572篇 |
1989年 | 77608篇 |
1988年 | 70807篇 |
1987年 | 69099篇 |
1986年 | 64444篇 |
1985年 | 61227篇 |
1984年 | 45332篇 |
1983年 | 38238篇 |
1982年 | 22639篇 |
1979年 | 39127篇 |
1978年 | 27493篇 |
1977年 | 23314篇 |
1976年 | 21546篇 |
1975年 | 22861篇 |
1974年 | 26868篇 |
1973年 | 25423篇 |
1972年 | 23808篇 |
1971年 | 21994篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
992.
邹城市预防艾滋病健康教育效果评价 总被引:6,自引:4,他引:2
目的评价预防艾滋病健康教育与行为干预效果。方法采用问卷方式对社区居民进行预防艾滋病信息的可及性及知信行的调查。结果社区居民艾滋病知晓率为97.41%,熟悉艾滋病传播途径的87.78%,62.78%的认为艾滋病病人或感染者和正常人享有一样的入学/就业权,38.70%的人愿意与感染艾滋病的同事继续共事,60.19%的人愿意与感染艾滋病的家人继续共同生活,最近3次性行为100%使用安全套者为26.48%,82.04%的人有医疗用血安全意识,64.81%的人有医疗器械安全意识。最想获取艾滋病预防措施、传播途径、病理知识、症状表现、治疗方法、检测途径及检测方法、疫情信息,新闻、电视公益广告、专题报道、反映艾滋病病人生活的电影或电视剧、科普材料、大型公益演出人们最喜欢。结论政府重视,多部门合作,组织机构健全,宣传教育广泛,干预措施到位,成效显著。 相似文献
993.
Efficacy of proton pump inhibitors for cellular proliferation and apoptosis in Barrett's oesophagus with different mucin phenotypes 总被引:1,自引:0,他引:1
994.
Oral Saygun Serdar Topaloglu Fatih M Avsar Hakan Ozel Sema Hucumenoglu Mustafa Sahin Suleyman Hengirmen 《Canadian journal of surgery》2006,49(2):107-112
BACKGROUND: Most duodenal injuries are managed with primary repair, but the degree of duodenal-wall injury may threaten the integrity of the primary repair. Therefore, we evaluated whether the primary repair site could be reinforced with histoacryl glue (HAG) or HAG with an expanded polytetrafluoroethylene (ePTFE) mesh. METHODS: Grade 3 duodenal injury in the second portion of the rat duodenum was chosen as a standard trauma model. Thirty-three male rats were divided into sham (n = 3), 2-layer primary repair (n = 10), 1-layer primary repair plus HAG application (n = 10) and ePTFE attached with HAG over the 1-layer primary repair site (n = 10) groups. Ten-day survival, adhesion grades and histological assessment were taken as outcome measures. RESULTS: A significant survival advantage was identified in the group that had an ePTFE graft attached with HAG over a 1-layer repair when compared with the group that had a 2-layer primary repair. Adhesion grades were found to be particularly increased in the group that had an ePTFE graft attached with HAG over the primary repair site, moderately increased in the primary repair plus HAG application group and lower in the 2-layer primary repair group. ePTFE graft application was found to be beneficial to coverage of the HAG-dependent empty spaces in the serosal layer. CONCLUSIONS: A primary repair site after duodenal trauma or a difficult duodenal stump can be reinforced with the application of HAG or ePTFE graft implantation with HAG. 相似文献
995.
A survey of plants used as wild vegetables was conducted in four districts of Botswana in August and September 2005. The objective was to determine which wild plants were used as vegetables in the study area, and to document their cooking and preservation methods. Fourteen species representing seven families were mentioned as wild vegetables. In addition, six species from four families had other uses in traditional medicine. The implications of the documented processing methods on the retention of nutrients in the vegetables are discussed. 相似文献
996.
C M Taylor 《Archives of disease in childhood》2006,91(3):277-8; author reply 277-8
997.
998.
主动呼吸控制技术(ABC)在肺癌放射治疗中的应用 总被引:1,自引:0,他引:1
目的:使用主动呼吸控制技术(aetive brething control,ABC)治疗非小细胞肺癌患者,评价呼吸运动时肺部肿瘤动度的影响及ABC技术的优势和可行性,并评价近期疗效和急性放射反应。方法:选择9例使用ABC技术联合三维造型放疗技术治疗的非小细胞系癌患者进行分析。CT定位扫描时分别采集ABC和自由呼吸(free breath.FB)状态下的图像,评价呼吸运动对肺部肿瘤动度和PTV边界的影响唾弃;并比较两种计划的DVH,放疗剂量为54-60Gy/18-20次。3Gy/次,1次/天,5天/周,定期随访,评价近期疗效及急性放射反应。结果:应用ABC技术后,隔肌的平均位移从FB时的43.5mm(20.0-32.0mm)降低为3.6mm(0.5-72.mm),胸壁的侧方位移从FB时的3.2mm(2.8-4.0mm)降低为1.2mm(0.5-1.6mm).PTV边界可以从FB时的1.5mm减少为0.75cm;肺的V20从21.8%降低为15.0%,减少了30.6%.中位随访6个月时,9例患者中有6例CR,3例PR.急性放射副反应都很轻微,仅为I-II.结论:在肺癌的精确放射治疗中,呼吸动度的影响不可忽视.而ABC系统可以有效的降低呼吸运动时治疗的影响,提高放疗的精确性,减少副反应.,但该系统使用较为复杂,延长了治疗的时间,个别患者不能忍受. 相似文献
999.
BCR-ABL activity and its response to drugs can be determined in CD34+ CML stem cells by CrkL phosphorylation status using flow cytometry. 总被引:2,自引:0,他引:2
A Hamilton L Elrick S Myssina M Copland H J?rgensen J V Melo T Holyoake 《Leukemia》2006,20(6):1035-1039
In chronic myeloid leukaemia, CD34(+) stem/progenitor cells appear resistant to imatinib mesylate (IM) in vitro and in vivo. To investigate the underlying mechanism(s) of IM resistance, it is essential to quantify Bcr-Abl kinase status at the stem cell level. We developed a flow cytometry method to measure CrkL phosphorylation (P-CrkL) in samples with <10(4) cells. The method was first validated in wild-type (K562) and mutant (BAF3) BCR-ABL(+) as well as BCR-ABL(-) (HL60) cell lines. In response to increasing IM concentration, there was a linear reduction in P-CrkL, which was Bcr-Abl specific and correlated with known resistance. The results were comparable to those from Western blotting. The method also proved to be reproducible with small samples of normal and Ph(+) CD34(+) cells and was able to discriminate between Ph(-), sensitive and resistant Ph(+) cells. This assay should now enable investigators to unravel the mechanism(s) of IM resistance in stem cells. 相似文献
1000.
Lisa A. Lang DDS MS David C. Holmes DDS MS Craig Passon DDS MS Robert M. Trombly DDS JD Jeffrey D. Astroth DDS MSPH Arnold F. Tavel DMD 《Journal of prosthodontics》2003,12(3):206-210
Using complete denture treatment as an introduction to clinical patient care for dental students, the purposes of the Complete Denture Prosthodontics Transition Clinic at the University of Colorado School of Dentistry are to reduce the time lapse between the preclinical complete denture prosthodontics course and the first denture patient experience, and to encourage development of student self-confidence and skills. In the 2002 spring semester, faculty at the University of Colorado School of Dentistry initiated the Complete Denture Prosthodontics Transition Clinic for DS-II (second-year) dental students, as an introduction to clinical patient care. Each patient was assigned to a team of two dental students. Three Division of Prosthodontics faculty members staffed each clinic session, providing a student-to-faculty ratio of approximately 6.6:1 and a patient-to-faculty ratio of approximately 3.3:1. All DS-II students in the Class of 2004 delivered their first complete dentures no later than 8 months (average, 184 days) after the last day of the preclinical complete denture prosthodontics course. The time from the diagnostic appointment through the denture placement appointment averaged 39 days for patients treated in this program, compared with an average of 98 days or more for previous classes. The program was successful in achieving the goal of reducing the time lapse between the preclinical complete denture prosthodontics course and the first denture patient experience. 相似文献