THE ROLE OF P_1-PURINERGIC RECEPTORS IN THE SPINAL MECHANISMS OF ACUPUNCTURE ANALGESIA

It has been extensively proved that electro-acupuncture elicit analgesia in bothextensive areas and local region via supraspinal structures and spinal cord.The present investigationwas to study the role of P_1-purinergic receptors in the spinal mechanisms of weak electroacupuncture-induced analgesia.Leg withdrawal latency(LWL)to noxious radiant heat focused on the ankle regionwas used to assess the effects of acupuncture and that of P_1-purinergic(adenosine)receptor antago-nists,theophylline and caffeine on the electro-acupuncture(EA)analgesia.EA prolonged the LWLby 16.7%±20.3%,with an after-effect lasting about 15 min.Both theophylline and caffeineblocked the EA-induced prolongation of LWL in a dose-dependent manner at the doses of 1.6-16 mg/kg.These results suggest that P_1-purinegic receptor is involved in the spinal mechanisms of weak EAproduced analgesia in the rat.     

RETINOBLASTOMALACTIC DEHYDROGENASE OF AQUEOUS HUMOUR AND ITS ISOENZYMES

Lactic dehydrogenase (LDH) activity in aqueoushumour and serum was measured of 24 patients withretinoblastoma, senile cataract, glaucoma, and cho-roid melanoma in addition to LDH isoenzyme fractions. The results were compared with those of the20 normal children. The ratio of aqueous humourLDH to serum LDH was 4.32+2.80, and that ofisoenzymes LDH4 to LDHl was greater than l. Theresults of our study suggested that the total LDHactivity and isoenzyme fractions in the aqueoushumour is of value in the diagnosis of retinobla&toma.     

新型聚胺基糖表面处理氧化纤维口服吸附剂对肾衰模型鼠…

理论推导了斜交共线式光热偏转信号垂直分量的表态式，并进行了实验验证，两者结果一致，分析并讨论了斜交共线式光热偏转构型的深层剖析能力的构成差分光度以消除溶剂吸收的可能性。     

处方管理办法(试行)

人们通常把高血压、高血脂、高血糖、冠心病叫做现代病或者说“富贵病”。现在,这些病代替了我们国家流行多年的传染病,并且在发展增长。这组病有时在同一患者身上发现,叫代谢紊乱综合征。它发病的病理生理基础是胰岛素抵抗。胰岛素抵抗是指一定量的胰岛素所产生的生物作用低于预计水平。让我们首先了解胰岛素有哪些生物作用。它的     

Sympathetic skin response in patients with myasthenia gravis★ A comparative analysis

BACKGROUND: The examination of sympathetic skin response is an important index for assessing the autonomic nerve function, and patients with myasthenia gravis are always accompanied by dysautonomia. Therefore, it will be important to know whether sympathetic skin response can be used as the index for the clinical evaluation of myasthenia gravis. OBJECTIVE: To investigate the diagnostic value of sympathetic skin response in the damage of autonomic nerve function of patients with myasthenia gravis. DESIGN: A case-controlled comparative observation. SETTING: Department of Neurology and Room of Nerve Electromyogram, the Affiliated Hospital of North Sichuan Medical College. PARTICIPANTS: Thirty outpatients or inpatients with myasthenia gravis were selected from the Department of Neurology, the Affiliated Hospital of North Sichuan Medical College from May 2006 to May 2007, including 9 males and 21 females, aged 8–72 years with a mean age of (28±5) years old. They were all accorded with the diagnostic standards of myasthenia gravis, accompanied by different severity of autonomic nerve symptoms, including poor skin nutrition, sweating of hands and feet, pyknocardia, persistent hypotension, abdominal pain, constipation, etc. They all had not taken any drug affecting the autonomic nerve function before the examination. Informed consents were obtained from all the patients. Meanwhile, 30 healthy physical examinees were enrolled as the normal control group, including 10 males and 20 females, aged 10–75 years with a mean age of (31±5) years old. Approval was obtained from the hospital ethic committee. METHODS: After admission, the patients were examined with sympathetic skin response using DANTEC keypoint 2.0 electromyography evoked potential apparatus (Danmark). The changes of the latency and wave amplitude of sympathetic skin response were observed. The subjects in the normal control group were examined with the same methods at physical examination. Abnormality was judged by the disappearance of wave form, latency longer than that in the normal control group by Mean±2.5SD, or wave amplitude lower than the average value in the normal control group by 50%. MAIN OUTCOME MEASURES: The results of the latency and wave amplitude of sympathetic skin response were compared between the patients with myasthenia gravis and normal controls. RESULTS: All the 30 patients with myasthenia gravis and 30 healthy physical examinees were involved in the final analysis of results. There were no significant differences between the left and right upper and lower limbs in both the myasthenia gravis group and normal control group (P > 0.05). In the myasthenia gravis group, the abnormal rate of sympathetic skin response was 37% (11/30), the latency was prolonged and the wave amplitude was decreased as compared with those in the normal control group, and there were significant differences (P < 0.01). CONCLUSION: Sympathetic skin response can be used as an electrophysiological index for judging the damages of autonomic nerve function in patients with myasthenia gravis.     

甲状腺疾病误诊误治4例分析

甲状腺疾病临床表现复杂多样，容易引起误诊误治。现结合临床病例，分析误诊误治的教训，希望引起医生对甲状腺疾病的重视。     

Transient Macular Edema after Laser In-Situ Keratomileusis

Purpose: To investigate the macular changes induced by laser in situ keratomileusisc(LASIK) procedure.Methods: Optical Coherence Tomography (OCT) was used to examine 27 eyes of 15LASIK patients before surgery, and 1 day, 1 week, 1 month after surgery.Results: The mean thick iness of neuroepithelial layer of macula was (195 ±24)microns, (178± 16) microns 1 day and 1 month after surgery, respectively, while thebaseline was (174 ± 12) microns. The increase in macular neuroepithelial thickness wascorrelated with the degree of myopia, but not with the duration of suction or thepostoperative BCVA.Conclusion: Mild macular edema is common in the first month following LASIK,especially in high myopia. However, no association with loss of BCVA has beenestablished. Eye Science 2003; 19: 20 - 24.     

老年人对脑外伤的耐受性

近年来老年人脑外伤的发病率有明显增高,但有关这方面的资料却非常少。本文报告1981年～1985年间收治的80～96岁脑外伤患者56例,女∶男=3∶2,占同期脑外伤入院病人的1～2％。老年人因     

Data Bank and Consulting System for Medical Management of Patiens with Acute Radiation Sickness

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肺血虚证治初探

肺血虚证，是肺气亏虚，气不生血，津液不足，生血物质减少所致止虚之谓。近年来，对肺血虚证的研究日趋活跃．已成为肺系学说研究的一个重要组成部分。肺病的辩证论治，临床上多侧重于虚实两端，而虚证又以肺气虚，肺阳虚，肺阳虚为主，很少给予肺血虚的位置。清代名医唐容川在《血证论》中虽有论及，但缺乏系统的分析和探研。故笔者兹将所辑资料，结合临床体会，试将肺血虚的证治探讨如下。1病机任说人之一身，不外气血耶。从生理而言，一是肺主气，气生血。所谓“中焦亦并胃中，出上焦之后，此所受之者，泌糟粕蒸津液，化其精微，上注于…