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A. Grubert K. Koch F. Fallenstein L. Spätling 《Archives of gynecology and obstetrics》1993,254(1-4):1438-1439
Ohne Zusammenfassung 相似文献
16.
Conclusions The peroneal nerves and their blood supply are at risk during high tibial osteotomies. Fixation of nerves by fibrous tissues,
compression by tendinous arcades of the peroneus longus tendon, and narrow passages for nerves crossing dense fibrous septa
are all factors which favor the development of peroneal nerve lesions. Intraoperative soft tissue retraction and pull by retractors
may damage nerves and vessels. The muscle branch for the extensor hallucis longus muscle is particularly at risk during the
fibular osteotomy since it runs directly on the bone. 相似文献
17.
Angelika Heese Ulrike Lacher Hans Uwe Koch Janna Kubosch Yasmin Ghane Klaus-Peter Peters 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》1996,47(11):817-824
Zusammenfassung
Die Typ I-Allergien gegen Latex sind in den vergangenen Jahren zu einem zunehmenden berufsdermatologischen Problem geworden,
zumal mindestens 10% der Angestellten im Gesundheitswesen betroffen sind. In der Dermatologischen Klinik der Universit?t Erlangen-Nürnberg
stieg die Anzahl der j?hrlich diagnostizierten Patienten mit Latexallergien von 1989 bis 1995 auf das 12fache, wobei der Anteil
der schweren, generalisierten Formen der Erkrankung von 10,7% (1989/1990) auf 44% (1994/1995) zunahm.
Unter den m?glichen Ausl?sern der Latexallergie (wasserl?sliche Proteine mit Molekulargewichten von 2 bis 200 kD) sind mindestens
5 Hauptproteine mit bereits bekannter Prim?rstruktur zu berücksichtigen. Zus?tzlich gibt es Hinweise für Markerproteine, die
in bestimmten Risikogruppen geh?uft zur Ausl?sung spezifischer IgE-Antik?rper führen (z.B. 46 kD-Protein in medizinischen
Berufen, 14,6 kD- und 27 kD-Proteine bei Kindern mit Spina bifida). Das Vorkommen von Kreuzreaktionen zwischen Latex und unterschiedlichen
Früchten (besonders Avocado, Kiwi, Banane, E?kastanie) bei 60 bis 70% der Latexallergiker ist bei der allergologischen Abkl?rung
und Beratung dieser Patienten zu beachten. Wesentliche Aspekte der Prophylaxe umfassen die konsequente Umstellung medizinischer
Einrichtungen auf ungepuderte Latexhandschuhe mit niedrigem Proteingehalt. Eine Zusammenstellung von OP- und Untersuchungshandschuhen,
welche Angaben über die von uns ermittelten Proteinkonzentrationen (modifizierte Lowry-Methode und Hochdruck-Flüssigkeits-Chromatographie,
HPLC) enth?lt, soll ein Leitfaden bei der Auswahl allergologisch geeigneter Handschuhe sein.
Eingegangen am 10. August 1996 Angenommen am 21. August 1996 相似文献
18.
R J Sevick A J Barkovich M S Edwards T Koch B Berg T Lempert 《AJR. American journal of roentgenology》1992,159(1):171-175
To characterize further the evolution of white matter lesions in neurofibromatosis type 1, we reviewed 68 MR images in 43 patients (age, 1-31 years), including 25 follow-up studies (mean interval, 27 months). Lesion number, location, morphology, signal characteristics, and contrast enhancement were assessed. Lesion characteristics and changes thereof were correlated with the patients' ages. Thirty-four patients (79%) had white matter lesions. These lesions were hyperintense on T2-weighted images, were isointense on T1-weighted images, and showed no mass effect or contrast enhancement in 31 patients; in three patients, T1-prolongation was observed (one with significant mass effect). None of the lesions evolved into a glioma. The most common locations were the cerebellum (49%), brainstem (22%), and internal capsule (19%). Nineteen patients had white matter lesions and follow-up studies. Lesions decreased in size or number in seven patients (average age, 13 years), showed no change in three (average age, 12 years), increased in size or number in four (average age, 5 years), and showed a mixed pattern (increased/decreased size/number) in four (average age, 7 years). White matter lesions in neurofibromatosis type 1 frequently increase in size or number early in childhood; this did not indicate neoplasia in our study. The lesions tend to resolve with increasing age. Lesion progression in a child more than 10 years old warrants close follow-up to rule out a neoplasm. 相似文献
19.
Role of alginate in infection with mucoid Pseudomonas aeruginosa in cystic fibrosis. 总被引:11,自引:2,他引:9 下载免费PDF全文
BACKGROUND: Chronic bronchopulmonary infection with mucoid, alginate producing Pseudomonas aeruginosa occurs characteristically in patients with cystic fibrosis. Alginate may be a virulence factor for P aeruginosa infection in such patients. METHODS: Forced vital capacity (FVC), nutritional state and the antibody response to P aeruginosa were determined at regular intervals from three years before chronic P aeruginosa infection to 10 years afterwards in 73 patients with cystic fibrosis. All patients were treated intensively with antipseudomonal chemotherapy during the study period. RESULTS: FVC was reduced in all patients who subsequently developed P aeruginosa infection before they acquired the infection, indicating significant pre-existing lung damage when compared with patients who remained free of P aeruginosa. Lung function and nutritional state remained unchanged after 10 years of infection, except in the patients who died of P aeruginosa lung infection. The FVC and height and weight of patients infected with nonmucoid strains of P aeruginosa were similar to those of uninfected patients. Patients infected with mucoid strains had poorer lung function and nutritional state for the first five years after infection compared with patients with nonmucoid strains. Such infection was also associated with greater IgG and IgA antibody responses to P aeruginosa standard antigen compared with nonmucoid infection. Concentrations of antibody to alginate were similar in patients with non-mucoid and mucoid infection. Noticeably increased concentrations of IgA antibodies to P aeruginosa standard antigen were observed early after the onset of infection in patients who subsequently died. CONCLUSION: Alginate producing P aeruginosa infection is associated with a hyperimmune response and poor clinical condition, suggesting that alginate production is a virulence factor in such infections in patients with cystic fibrosis. 相似文献
20.
Background: diabetic patients with end-stage renal
failure (ESRD) have a high cardiovascular morbidity and mortality. The
underlying mechanisms are not completely elucidated. The aim of our study
was to define predictors of death in diabetic patients with end-stage renal
disease. Patients and methods: We preformed a
prospective study in 35 dialysis centres in Germany between 1985 and 1994.
To evaluate predictors and risk factors in this population we examined 412
diabetic patients at the time of admission to dialysis treatment
(peritoneal dialysis (PD) or haemodialysis (HD)). Classification of the
type of diabetes was done according the criteria of the National Diabetes
Data Group [1,2]. Items assessed at the time of admission were coronary
artery disease (CAD), peripheral occlusive disease (POD), and stroke. CAD
was defined as a history of myocardial infarction with the corresponding
changes in the ECG or luminal narrowing by more than 50% in at least one
coronary artery upon coronarangiography; POD was defined as claudication
and/or brachial-tibial ratio (BTR) less than 0.9 or a history of
amputation. Assessment of the nutritional state comprised body mass index,
skinfold thickness of the upper arm and lateral thorax area, and urea
concentration. Cholesterol, HDL, LDL, apolipoprotein A (ApoA-I) and B
(ApoB), triglycerides, lipoprotein (a) (Lp(a)), and fibrinogen were
measured. As an index of disturbed cardiac innervation beat-to-beat
variation was measured. Outcome measurements were causes of death (i.e.
cardiac and non-cardiac) and time of survival.
Results: One hundred and eighty of 412 (44%) patients
died during the observation period Patients who died were older
(61±12 versus 53±15 years P
lt;0.0001), had lower skin fold thickness (13.1±6.0
versus 15.1±7.2 mm P <0.04), lower
ApoA-I (100±35 versus 111±32
mg/dl P <0.005) and higher fibrinogen (515±156
versus 451±155 mg/dl P <0.02). Type
II diabetic patients had a lower mean survival time than type I (34
versus 66 months P <0.0006). The mode of renal
replacement therapy (PD or HD) had no adverse effect on survival time.
Survivors less frequently had a history of CAD, POD and stroke than
non-survivors. In multivariate analysis ApoA-I, fibrinogen ,age and stroke
were independent predictors of cardiac and non-cardiac death in diabetic
patients with end-stage renal failure. Lipid values and nutritional state
did not independently predict the overall and cardiovascular mortality.
Conclusion: This study in dialysed diabetic patients
identified several predictors of death, some of which are susceptible to
intervention. 相似文献