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961.
Objective. To evaluate the results of operative treatment of spinal fracture-dislocation without neumlogic deficits. Metods. Eighteen patients with spinal fracture-dislocation were neurologically intact at the time of injury, and all were treated operatively. The fracture sites were:8 cases in cervical spine, 3 cases in thoracic spine, and 7 cases in lumbar spine. Eight patients with cervical injuries had variant degrees of forward slide and kyphotic deformity. Of the 10 thoracic and lumbar fractures, one had lateral dislocation, 4 cases with kyphotic deformities, 5 cases withspinal canal compromise averaged 50% (ranging from 40% to 70% ).Results. The aveiage period of follow-up was 4.4 years with a range of 11 months to 13 years. All the patients returned to full-time work. No patient developed neurologic deterioration. Kyphotic deformity was corrected in the 4 cases, and no progressive kyphosis was noted. There was no operation-related complication. The averaged post-opera-five hospitalization time was 13 days. Conclusions. Despite the rare incidence of spinal fracture-dislocation without neurologic deficits, we suggested that kind of fracture be considered unstable fracture because of its potential risk of delayed neurologic deterioration and kyphotic deformity, and be treated operatively to restore the sagittal alignment and the stability of the spine. 相似文献
962.
INHIBITORY EFFECT OF FLUVASTATIN ON AORTIC INTIMAL THICKENING IN NORMOCHOLESTEROLEMIC RABBITS 总被引:1,自引:0,他引:1
Objective, The anti-atherosclerotic effect of fluvastatin at doses insufficient to lower serum cholesterol on the catheter-induced intimal thickening and possible mechanism were investigated in abdominal aorta of rabbits. Methods. Fifty-six rabbits were randomly divided into eight groups( n = 7, each). Fluvastatin was given mixed with food at daily dose of 8mg/kg starting 5 days before catheterization. Light microscope, immanohistochemistry, transmis-sion electron microscope and RT-PCR assay were applied to assess vascular smooth muscle cell (VSMC) proliferation and apoptosis, as well as oncogene expression in vascular wall. Results. At day 10 and day 15 after catheter induced denudation intima/media( I/M) thickness ratio was obviously higher, and also the percentage of PCNA-positive cells and TUNEL-positive cells in media was significantly higher compared with controls. The intimal hyperplasia was mostly composed of α-SM-actin-pesitive cells. In rabbits given flu-vastatin I/M ratio and the percentage of these positive cells significantly decreased compared with those without fluvas-tatin.The overexpression of proto-oncogene H-ras mRNA and decreased expression of anti-oncogene p53 mRNA were found after vascular injury, whereas fluvastatin significantly reduced H-ras mRNA and increased p53 mRNA expres-sion. Conclusion. Proliferation of VSMC in the media and the migration to the intima can be inhibited, and apoptosis of VSMC be induced by short-term use of fluvastatin after balloon catheter denudation, independent of serum lipid change. The underlying mechanism is presumably associated With the influence of fluvastatin on oncogene expression in the injured vascular Wall. 相似文献
963.
目的:探讨改善羊水过少围产儿预后,降低死亡率的终止妊娠方法。方法:抽取1988年3月~1966年1月间住院分娩产妇9472例,其中羊水过少345例,发生率3.65%。对345例羊水过少围产儿预后及分娩方式进行探讨。结果:345例羊水过少,经阴分娩153例,剖宫产192例,剖宫产率为55.65%。胎儿窘迫143例(41.2%),新生儿窒息185例(53.6%),新生儿死亡14例(4.1%)。对照组500例,肥儿窘迫34例(6.8%),新生儿窒息34例(6.8%),新生儿死亡4例(0.8%),两组相比羊水过少围产儿发病率显著升高(P〈0.05,P〈0.01)。结论:羊水过少胎儿窘迫,新生儿窒息及死亡率均高,适时剖宫产能改善围产儿预后。 相似文献
964.
目的 探讨肝硬化患者血清丙酮酯激酶(PK)活必级临床意义。方法 应用酶偶联速率法测定93例肝硬化患者和53例正常人的血清PK活性。结果 肝硬化患者血清PK活性明显降低(P〈0.001),并随肝功能减退而递减,分别与血清白蛋白及镁呈正相关(r=0.346,P〈0.01,r=0.252,P〈0.05);伴有腹水者明显低于无伴腹水者(P〈0.005),肝炎后肝硬化明显低于酒精性肝硬化(P〈0.01)。结 相似文献
965.
谷氨酰胺对大鼠急性坏死性胰腺炎肠道细菌移位的影响 总被引:3,自引:2,他引:1
目的 观察谷氨酰胺(GLN)对急性坏死性胰腺炎(ANP)大鼠肠道细菌称位的影响。方法 将实验大鼠120只,随机分成对照组、ANP组及GLN组,每组各40只,ANP模型采用结扎胰胆管诱发,GLN组制作ANP后灌入GLN,观察3组肠粘膜组织学和DNA含量,肠系膜淋巴结,胰腺组织细菌培养及吖啶橙标记菌实验。结果 ANP后72h,肠粘膜出现明显损伤,DNA含量下降,肠系膜淋巴结,胰腺组织细菌培养计数明显升 相似文献
966.
967.
968.
农村饮水水质现状分析 总被引:9,自引:0,他引:9
在全国26个省、市、自治区的180个县进行农村饮水卫生监测,监测区总人口为8939万人。其中以地下水为饮用水源的占69.6%,集中式供水的人口占47.1%。按照《农村实施〈生活饮用水卫生标准〉准则》进行分级,饮用不合格水的人口占42.7%。12项监测指标中,微生物指标超标严重,总大肠菌群超过3个/L的供水人口占51.8%;细菌总数超过1×105个/L(100个/ml)的供水人口占39.1%。有机污染普遍存在,饮水耗氧量超过3mg/L的供水人口占21.5%。部分地区氟化物含量过高,天津市所辖农村饮用氟化物大于1.0mg/L水的人口比例超过70%。 相似文献
969.
Yuuki Kawamura Jun Suzuki Sumiko Kimura Koscak Maruyama 《Journal of muscle research and cell motility》1994,15(6):623-632
Summary In obliquely striated muscle of polychaete, Neanthes sp., three kinds of connectin (titin)-like high molecular weight proteins, 4000 kDa, 1200 kDa and 700 kDa, were detected by SDS gel electrophoresis and immunoblots using antibodies to vertebrate skeletal muscle connectin and antiserum to the protein in question. The 700 kDa protein was isolated and characterized as a sheet-rich filament 170 nm long and 4 nm wide. Using polyclonal antibodies to the 700 kDa protein, the binding of the immunogold to the thick filament was only demonstrated in high ionic strength relaxing solution which solubilized some myosin. This observation suggested that the 700 kDa protein was localized below the layers of myosin in the thick filament and this localization is different from that of twitchin of C. elegans bodywall muscle that is on the surface of thick filament. The 4000 kDa protein was identified as a very thin filament linking the thick filament to the dense body. The very thin filaments were visualized in gelsolin-treated actin filament-free fibres. The 1200 kDa protein was located in the periphery of the dense body. A model of the elastic filament in polychaete bodywall muscle is presented. 相似文献
970.
Jun Hatazawa Hiroshi Itoh Eku Shimosegawa Iwao Kanno Matsutaroh Murakami Shuichi Miura Hidehiro Iida Toshio Okudera Atsushi Inugami Toshihide Ogawa Hideaki Fujita Yuichi Satoh Ken Nagata Yutaka Hirata Kazuo Uemura 《Annals of nuclear medicine》1994,8(3):213-217
We studied the brain uptake of amino acid in a patient with acute cerebral infarction with L-[2-(F-18)] fluorophenylalanine and positron emission tomography. The increased accumulation of the ligand was specifically found in the peri-infarct area where oxygen metabolism was still maintained but decreased later in the 72-day follow-up period. The kinetic analysis revealed that increased accumulation was not due to increased transport from the blood to the brain but to delayed washout from the brain to the blood. Although the mechanism is still unknown, abnormally high accumulation of L-[F-18]fluorophenylalanine may predict delayed neuronal changes after ischemic insults of the brain. 相似文献