全文获取类型
收费全文 | 365071篇 |
免费 | 21940篇 |
国内免费 | 670篇 |
专业分类
耳鼻咽喉 | 5296篇 |
儿科学 | 12276篇 |
妇产科学 | 11533篇 |
基础医学 | 52607篇 |
口腔科学 | 8929篇 |
临床医学 | 31031篇 |
内科学 | 70068篇 |
皮肤病学 | 7414篇 |
神经病学 | 27737篇 |
特种医学 | 14003篇 |
外国民族医学 | 48篇 |
外科学 | 58743篇 |
综合类 | 8592篇 |
现状与发展 | 1篇 |
一般理论 | 255篇 |
预防医学 | 25711篇 |
眼科学 | 8295篇 |
药学 | 25311篇 |
中国医学 | 888篇 |
肿瘤学 | 18943篇 |
出版年
2021年 | 3925篇 |
2019年 | 3749篇 |
2018年 | 5381篇 |
2017年 | 3924篇 |
2016年 | 4353篇 |
2015年 | 4902篇 |
2014年 | 6775篇 |
2013年 | 10294篇 |
2012年 | 13747篇 |
2011年 | 14309篇 |
2010年 | 8805篇 |
2009年 | 7929篇 |
2008年 | 12966篇 |
2007年 | 14097篇 |
2006年 | 13795篇 |
2005年 | 13394篇 |
2004年 | 12844篇 |
2003年 | 11985篇 |
2002年 | 11325篇 |
2001年 | 13857篇 |
2000年 | 14120篇 |
1999年 | 12031篇 |
1998年 | 3750篇 |
1997年 | 3443篇 |
1996年 | 3218篇 |
1995年 | 3058篇 |
1994年 | 2846篇 |
1993年 | 2629篇 |
1992年 | 8687篇 |
1991年 | 8820篇 |
1990年 | 8567篇 |
1989年 | 8361篇 |
1988年 | 7594篇 |
1987年 | 7338篇 |
1986年 | 6991篇 |
1985年 | 6871篇 |
1984年 | 5193篇 |
1983年 | 4479篇 |
1982年 | 2987篇 |
1979年 | 4633篇 |
1978年 | 3502篇 |
1977年 | 2993篇 |
1976年 | 2709篇 |
1975年 | 3049篇 |
1974年 | 3532篇 |
1973年 | 3546篇 |
1972年 | 3256篇 |
1971年 | 3061篇 |
1970年 | 2922篇 |
1969年 | 2665篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
81.
Heidi J Kalkwarf John A Shepherd Didier Hans Elena Gonzalez Rodriguez Joseph M Kindler Joan M Lappe Sharon Oberfield Karen K Winer Babette S Zemel 《Journal of bone and mineral research》2022,37(4):776-785
Trabecular bone score (TBS) is used for fracture prediction in adults, but its utility in children is limited by absence of appropriate reference values. We aimed to develop reference ranges for TBS by age, sex, and population ancestry for youth ages 5 to 20 years. We also investigated the association between height, body mass index (BMI), and TBS, agreement between TBS and lumbar spine areal bone mineral density (aBMD) and bone mineral apparent density (BMAD) Z-scores, tracking of TBS Z-scores over time, and precision of TBS measurements. We performed secondary analysis of spine dual-energy X-ray absorptiometry (DXA) scans from the Bone Mineral Density in Childhood Study (BMDCS), a mixed longitudinal cohort of healthy children (n = 2014) evaluated at five US centers. TBS was derived using a dedicated TBS algorithm accounting for tissue thickness rather than BMI. TBS increased only during ages corresponding to pubertal development with an earlier increase in females than males. There were no differences in TBS between African Americans and non-African Americans. We provide sex-specific TBS reference ranges and LMS values for calculation of TBS Z-scores by age and means and SD for calculation of Z-scores by pubertal stage. TBS Z-scores were positively associated with height Z-scores at some ages. TBS Z-scores explained only 27% and 17% of the variance of spine aBMD and BMAD Z-scores. Tracking of TBS Z-scores over 6 years was lower (r = 0.47) than for aBMD or BMAD Z-scores (r = 0.74 to 0.79), and precision error of TBS (2.87%) was greater than for aBMD (0.85%) and BMAD (1.22%). In sum, TBS Z-scores provide information distinct from spine aBMD and BMAD Z-scores. Our robust reference ranges for TBS in a well-characterized pediatric cohort and precision error estimates provide essential tools for clinical assessment using TBS and determination of its value in predicting bone fragility in childhood and adolescence. © 2022 American Society for Bone and Mineral Research (ASBMR). 相似文献
82.
83.
84.
Peffault de Latour Rgis Huynh Lynn Ivanova Jasmina I. Totev Todor Bilginsoy Mehmet Antin Joseph Roy Anuja Duh Mei Sheng 《Annals of hematology》2020,99(4):743-752
Annals of Hematology - This study assessed treatment patterns and healthcare resource utilization (HRU) of patients with severe aplastic anemia (SAA) with insufficient response to immunosuppressive... 相似文献
85.
86.
C. Jacquet F. Goehringer E. Baux J.A. Conrad M.O. Ganne Devonec J.L. Schmutz G. Mathey H. Tronel T. Moulinet I. Chary-Valckenaere T. May C. Rabaud 《Médecine et maladies infectieuses》2019,49(2):112-120
Objective
The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.Patients and methods
We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.Results
A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.Conclusions
This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses. 相似文献87.
88.
89.
N. V. Bashmakova G. N. Chistiakova I. A. Gazieva Y. M. Trapeznikova D. O. Mazurov 《Gynecological endocrinology》2015,31(10):31-33
AbstractThis study was undertaken to compare the concentrations of pro- and anti-angiogenic growth factors, nitric oxide (NO) stable metabolites in maternal serum and embryonic left ventricular (LV) isovolumic relaxation time (IRT, ms) during the first trimester in two groups of women: with pregnancy conceived by assisted reproductive technologies (ART, n?=?39) and normally conceived (control group, n?=?68) pregnancy. The concentration of vasoconstrictor endothelin 1 was 45.5 times more in ART than in control group. On the contrary, the concentrations of NO stable metabolites in ART were 1.9 times less than in control women. The assessment of angiogenic suppressors in ART women demonstrates the decrease in s-endoglin concentration was 1.6 times and in soluble receptor to vascular endothelial growth factor concentration was 2.0 times in comparison with control group. There was a significant increase in LV IRT in ART embryos in comparison to control ones. These data suggest significant changes in pro- anti-angiogenic factors balance and increase in vascular impedance in ART-conceived embryos. 相似文献
90.