腰椎管减压植骨坚强连接(SOCON)复位器治疗腰椎滑脱

[目的]观察应用腰椎管减压、横突间植骨和坚强连接(SOCON)复位器治疗腰椎滑脱合并腰椎管狭窄患者的早期疗效.[方法]对18例腰椎滑脱患者采用腰椎管减压,横突间植骨和SOCON内固定手术.[结果]18例患者中,15例症状完全消失,达83%,14例Ⅰ°滑脱完全复位,3例Ⅱ°滑脱完全复位,解剖复位率达94%.[结论]SOCON复位器治疗腰椎滑脱,效果良好,复位满意.     

荧光定量PCR技术在检测HCV—RNA中的应用

目的 评价荧光定量ＰＣＲ技术测定ＨＣＶ－ＲＮＡ水平的价值,探讨ＰＢＭＣ中检出ＨＣＶ－ＲＮＡ的意义。方法 采用荧光定量ＫＲ及ＲＴ－ＰＣＲ技术同时检测８７例血液透析患者的血清和淋巴细胞中ＨＣＶ－ＲＮＡ。结果血清、淋巴细胞中ＨＣＶ－ＲＮＡ的荧光定量ＰＣＲ检出率（４９．４％、６９．０％）,分别高于相应标本中ＨＣＶ－ＲＮＡ的ＲＴ－ＰＣＲ阳性率（３３．３％、３５．６％）（Ｐ ＜０．０５）。血清、淋巴细胞中同时检出ＨＣＶ－ＲＮＡ的一致率,荧光定量ＰＣＲ法（３１．０％）显著高于ＲＴ－ＰＣＲ定性法（６．９％）（Ｐ＜０．００１）． 荧光定量ＰＣＲ法,淋巴细胞中ＨＣＶ－ＲＮＡ检出率高于血清（Ｐ＜０．０１）。结论 与 ＲＴ－ＰＣＲ相比,荧光定量ＰＣＲ技术检测 ＨＣＶ－ＲＮＡ敏感性较高,对ＰＢＭＣ内ＨＣＶ－ＲＮＡ检测有利于提高ＨＣＶ检测的阳性率。     

准分子激光原位角膜磨镶术创面愈合机制的免疫组化实验

[目的]研究准分子激光原位角膜磨镶术(1aser in situ keratomileusis,LASIK)后角膜创面的愈合机制.[方法]对10只兔右眼施行IASIK手术,分别于术后1 d、1周、1个月、3个月和6个月取标本,应用病理学和免疫组化的方法研究及观察角膜基质成分的变化.[结果]LASIK后1周中央区角膜有少量的角膜细胞出现及产生少许Ⅲ型胶原及纤维连接蛋白,术后1～3个月时达高峰,6个月时明显减少.[结论]LASIK后,角膜愈合反应极轻,因而较少引起角膜混浊的发生.     

The association between plant-based diet and erectile function in Chinese young healthy men: A population-based study

The study was designed and conducted to evaluate the plant-based diet status and its association with erectile function (EF) in Chinese young healthy men. From July 2018 to May 2020, 116 objectively proved physically and psychologically healthy men were selected. Clinical questionnaires, detailed physical examinations and blood tests were all assessed. An overall plant-based diet index (PDI) and a healthful plant-based diet index (hPDI) were developed from each participant to measure plant-based diet quantitatively. The EF was measured by both the International Index of Erectile Function-5 (IIEF-5) and the surrogated measures of endothelial function, peripheral levels of nitric oxide (NO) and E-selectin. In subjects, the mean PDI and hPDI were 53.8 ± 8.2 and 54.7 ± 8.9 respectively. Results of multivariate analysis showed that both PDI and hPDI were negatively associated with BMI (all p < .05), but had no relationships with NO, E-selectin, TT levels and IIEF-5 scores (all p > .05). In a subgroup of male population, Chinese young healthy men, the plant-based diet, measured by PDI and hPDI, was not related to erectile function. The population can adhere to plant-based diet to keep healthy without concerns of negative influence on erectile function.     

Effect of photobiomodulation on CCC-ESF reactive oxygen species steady-state in high glucose mediums

Lasers in Medical Science - Delayed wound healing is one of the most challenging complications of diabetes mellitus (DM) in clinical medicine, and it is related to the excessive generation of...     

Multivisceral resection for locally advanced gastric cancer: A retrospective study

BackgroundMultivisceral resection may be the exclusive radical procedure for cT4b gastric cancer patients. However, most surgeons refuse to select surgery because of the theoretical higher mortality, morbidity and poorer prognosis.MethodsWe retrospectively reviewed cT4b gastric cancer patients who underwent surgery from January 1,1997 to December 31,2018. The primary endpoint was overall survival. Short-term results and prognostic values of clinical and pathologic factors were also analyzed.ResultsPatients underwent multivisceral resection had an acceptable mortality and morbidity. The overall 5-year survival rate of multivisceral resection was higher than that of palliative surgery (P < 0.05). And independent prognostic factors of multivisceral resection were R+ resection, extensive lymph node involved (>15), vascular cancer emboli, and postoperative chemotherapy.Conclusions: cT4b gastric cancer patients underwent multivisceral resection experience acceptable mortality and morbidity. The independent prognostic factors for multivisceral resection were completeness of resection, extensive lymph node involvement (>15), vascular cancer emboli, and postoperative chemotherapy.     

ASO Visual Abstract: Development and Validation of Web-Based Nomograms for Predicting Cause-Specific Mortality in Surgically Resected Nonmetastatic Invasive Breast Cancer: A Population-Based Study

Annals of Surgical Oncology -     

Distal oblique osteotomy versus cheilectomy for moderate-advanced hallux rigidus: A 2-year propensity-score-matched study

BackgroundThe surgical treatment of moderate-advanced hallux rigidus is controversial. Cheilectomy is widely used but has recurrence rates of up to 30%. Dorsal oblique metatarsal osteotomy (DOO) has also shown good results, however, there is no study comparing outcomes of the DOO against cheilectomy.MethodsThis was a retrospective propensity score matched study based on registry data from a single tertiary institution. Between 2007 and 2017, all patients who had undergone dorsal cheilectomy or DOO for hallux rigidus were included. Patients with previous foot surgery, revision surgeries, and concomitant surgical procedures were excluded. Clinical outcomes, complication rates, revision rates and patient satisfaction were assessed at 2 years postoperatively.ResultsThere were 44 patients (34 cheilectomy, 10 DOO). After propensity score matching, 17 cheilectomy and all 10 DOO cases were selected for comparison. Patients in both groups had a significant improvement in visual analogue pain scores (VAS) and AOFAS 1st toe scores 2-years post-operatively (P < 0.001) with high levels of post-operative satisfaction (85.1%). Overall there were no statistically significant differences in post-operative scores, improvement in scores, complication rates, revision rates, and levels of patient satisfaction between groups.ConclusionsBoth the DOO and cheilectomy give similarly good outcomes for moderate-advanced hallux rigidus. Further studies are needed to elucidate differences in indications for each procedure.     

Preparation of Battery-Grade FePO4·2H2O Using the Stripping Solution Generated from Resource Recycling of Bauxite Residue

Bulletin of Environmental Contamination and Toxicology - A novel process for the high-value-use of iron from bauxite residue was proposed in this work. The process was trying to use the...