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991.
Zhang Naidan Sun Jiaxiang Ji Chaixia Bao Xiao Yuan Chenliang 《Clinical rheumatology》2022,41(11):3451-3460
Clinical Rheumatology - The aim of this study was to develop and assess a risk nomogram of bacterial infection in patients with ANCA-associated vasculitis (AAV) in southwest China. We established a... 相似文献
992.
Obi Chukwuemeka A. Bulsara Kishen Izard Stephanie Delicce Anthony Smith Alexander Kim Eun Ji 《Journal of thrombosis and thrombolysis》2022,53(3):683-689
Journal of Thrombosis and Thrombolysis - Mechanical fall is common among elders and has been associated with a lack of anticoagulant therapy among patients with atrial fibrillation (AF). However,... 相似文献
993.
Sang-Il Ahn Se Jin Lim Gyo-Jeong Gu Ji-Soo Kim Ji Hun Paek Songmun Kim 《Food and Agricultural Immunology》2015,26(4):496-503
Inflammation is involved in numerous diseases including cancer. Inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) play important roles in the development of certain inflammatory diseases. Eupatorium makinoi, which belongs to a family of Asteraceae plants, is used medicinally in East Asia. We investigated the effects of an ethanol extract of E. makinoi (EEM) on nuclear factor-kappa B (NF-κB) activation and the expression of iNOS and COX-2 with lipopolysaccharide (TLR4 agonist) in murine macrophages. EEM suppressed NF-κB activation and iNOS and COX-2 expression induced by LPS. These results suggest that EEM may regulate TLR4 signalling pathways and this may be a useful strategy for anti-inflammatory therapies. 相似文献
994.
目的:观察大鼠脑缺血再灌注损伤后皮质微血管的变化,探讨丁苯酞对其作用。方法:线栓法制备大鼠脑缺血再灌注模型;单宁酸-氯化铁媒染法显示大脑皮质微血管,Mivnt图像分析系统定量分析微血管密度(MVD)和微血管面积密度(MVA);十湿重法检测脑含水量,透射电镜观察血脑屏障超微结构。结果:与假手术组相比,缺血再灌注组大鼠皮质微血管绝大部分闭合或僵直,MVD和MVA显著下降,脑含水量明显升高,电镜观察微血管腔狭窄,内皮细胞核固缩。丁苯酞组微血管形态好转,MVD和MVA升高,脑水肿和血脑屏障损伤程度均减轻。结论:丁苯酞可改善大鼠脑皮质微血管形态,减轻脑水肿和血脑屏障损伤,对脑缺血再灌注损伤有一定的预防性保护作用。 相似文献
995.
Ji Hyun Kim Phern-Chern Tor Joel King Jeong Seok Seo 《Journal of Korean medical science》2015,30(5):632-638
The definition of a "good" psychiatrist has varied over the past decades due to changing roles of psychiatrists. Studies on the qualities of "good" psychiatrists have been completed in many countries. However, no such study has been undertaken in Korea. In Korea, recent growing interest in psychiatry demands the identification of qualities for a good psychiatrist. The purpose of this study was to define the qualities of a good psychiatrist in Korea, subsequently facilitating the improvement of psychiatric training programs. The questionnaire was based on a Singaporean survey with the permission from the original authors. Respondents were divided into patient group and psychiatrist group. The 40-item questionnaire contained items grouped into four themes: Professional, Personal Values, Academic Executive and Relationship. Of the four themes, both patient and psychiatrist groups considered Professional as the most important, whereas Academic Executive as the least important. The mean scores for all items of each theme in the patient group were higher than those in the psychiatrist group, reflecting higher expectations for good psychiatrist in the patient group. Patients emphasized Relationship more than psychiatrists did. It is concluded that a good psychiatrist in Korea can be defined as "a good communicator and listener with a professional manner, who respects confidentiality and has good doctor-patient relationships."
Graphical Abstract
相似文献996.
Min-Soo Kim Jong Seok Lee Sang Beom Nam Hyo Jong Kang Ji Eun Kim 《Journal of Korean medical science》2015,30(8):1197-1202
Size selection of the laryngeal mask airway (LMA) Classic based on actual body weight remains a common practice. However, ideal body weight might allow for a better size selection in obese patients. The purpose of our study was to compare the utility of ideal body weight and actual body weight when choosing the appropriate size of the LMA Classic by a randomized clinical trial. One hundred patients with age 20 to 70 yr, body mass index ≥25 kg/m2, and the difference between LMA sizes based on actual weight and ideal weight were allocated to insert the LMA Classic using either actual body weight or ideal body weight in a weight-based formula for size selection. After insertion of the device, several variables including insertion parameters, sealing function, fiberoptic imaging, and complications were investigated. The insertion success rate at the first attempt was lower in the actual weight group (82%) than in the ideal weight group (96%), even it did not show significant difference. The ideal weight group had significantly shorter insertion time and easier placement. However, fiberoptic views were significantly better in the actual weight group. Intraoperative complications, sore throat in the recovery room, and dysphonia at postoperative 24 hr occurred significantly less often in the ideal weight group than in the actual weight group. It is suggested that the ideal body weight may be beneficial to the size selection of the LMA Classic in overweight patients (Clinical Trial Registry, ). NCT 01843270
Graphical Abstract
相似文献997.
Ran-hui Cha Joon-Sung Joh Ina Jeong Ji Yeon Lee Hyoung-Shik Shin Gayeon Kim Yeonjae Kim Critical Care Team of National Medical Center 《Journal of Korean medical science》2015,30(12):1807-1814
Some cases of Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) infection presented renal function impairment after the first MERS-CoV patient died of progressive respiratory and renal failure. Thus, MERS-CoV may include kidney tropism. However, reports about the natural courses of MERS-CoV infection in terms of renal complications are scarce. We examined 30 MERS-CoV patients admitted to National Medical Center, Korea. We conducted a retrospective analysis of the serum creatinine (SCr), estimated glomerular filtration rate (eGFR), urine dipstick tests, urinary protein quantitation (ACR or PCR), and other clinical parameters in all patients. Two consecutive results of more than trace (or 1+) of albumin and blood on dipstick test occurred in 18 (60%) (12 [40%]) and 22 (73.3%) (19 [63.3%]) patients, respectively. Fifteen (50.0%) patients showed a random urine ACR or PCR more than 100 mg/g Cr. Eight (26.7%) patients showed acute kidney injury (AKI), and the mean and median durations to the occurrence of AKI from symptom onset were 18 and 16 days, respectively. Old age was associated with a higher occurrence of AKI in the univariate analysis (HR [95% CI]: 1.069 [1.013-1.128], P = 0.016) and remained a significant predictor of the occurrence of AKI after adjustment for comorbidities and the application of a mechanical ventilator. Diabetes, AKI, and the application of a continuous renal replacement therapy (CRRT) were risk factors for mortality in the univariate analysis (HR [95% CI]: diabetes; 10.133 [1.692-60.697], AKI; 12.744 [1.418-114.565], CRRT; 10.254 [1.626-64.666], respectively). Here, we report renal complications and their prognosis in 30 Korean patients with MERS-CoV. 相似文献
998.
Seok-Chan Hong Jeffrey D. Suh Sochung Chung Seung-Hoon Lee Ji Ho Choi Jeong In Oh In-Tae Kim Jin Kook Kim Jae Hoon Cho 《Clinical and experimental otorhinolaryngology》2015,8(4):381-384
Objectives
To evaluate the association between catecholamine levels and skin prick test results among children.Methods
Two hundred eight first grade children from one elementary school were invited to participate in this study. Skin prick test (SPT) for six allergens (2 house dust mites, cat, dog, mugwort, and pollen mixture) was performed, and patient demographic information was recorded. The parents were surveyed using questionnaires about rhinitis-related symptoms. Finally, venous blood sampling was done to measure catecholamine levels (epinephrine, norepinephrine, and dopamine) by high-performance liquid chromatography.Results
Out of 208 children, 174 (106 boys and 68 girls) enrolled in this study. Ninety-six of the children (55%) had negative SPT (nonsensitization group), while 78 (45%) had a positive SPT to at least one of six allergens (sensitization group). The diagnosis of chronic rhinitis was more prevalent in the sensitization group (35.9%) than nonsensitization group (26.0%), however the finding was not significant (P=0.186). Epinephrine levels were decreased between the sensitization group compared to the nonsensitization group (P=0.004). There was no difference in norepinephrine and dopamine levels (P>0.05).Conclusion
Epinephrine levels are lower in children with positive SPT compared to controls, however, the level of the catecholamine was not associated with the presence or absence of rhinitis symptoms. 相似文献999.
Ji Ho Choi Seung Hoon Lee Jae Hoon Cho Sung Wan Kim Kyu Sup Cho Soo Kweon Koo Tae-Bin Won Jeong-Whun Kim Hyo Yeol Kim Yoo Suk Kim Yoo-Sam Chung Chae-Seo Rhee 《Clinical and experimental otorhinolaryngology》2015,8(4):370-375
Objectives
To evaluate the effect of obstructive sleep apnea (OSA) surgery on long-term (5-year) subjective outcomes, including sleep disordered breathing (SDB) symptoms and other complications, in patients with OSA.Methods
We enrolled patients who underwent diagnostic polysomnography for OSA between January 2006 and December 2006 in ten hospitals. Patients either were treated for OSA or were not treated for OSA. All patients completed a brief telephone survey regarding their SDB signs and symptoms (e.g., snoring, apnea, nocturnal arousals, and daytime sleepiness), positive airway pressure (PAP) compliance, and any adverse effects of either the surgery or PAP. A positive subjective outcome for either surgery or no treatment was taken to be the alleviation of apnea, defined as a ≥50% increase in score. A positive subjective outcome (compliance) for PAP was defined as a PAP usage of ≥4 hours per night and ≥5 days per week.Results
A total of 229 patients were included in this study. Patients were divided into three groups: a surgery group (n=87), a PAP group (n=68), and a control (untreated) group (n=74). The surgery group exhibited significant improvement in all SDB symptoms compared with the control group. The long-term subjective outcomes of the surgery (52.9%) and PAP (54.4%) groups were significantly better than those of the control group (25.0%). The subjective outcome of the surgery group was not significantly different from that of the PAP group. The overall surgical complication rate was 23.0% (20 of 87) in the surgery group, and 55.0% (22 of 40) of all patients with PAP experienced adverse effects.Conclusion
The extent of SDB symptoms was consistently improved in patients with OSA at 5 years postsurgery. Information about the potential long-term subjective outcomes should be provided to patients when considering surgery. 相似文献1000.
Ho Yun Lee Ji Chan Kim Dong Sik Chang Chin Saeng Cho 《Clinical and experimental otorhinolaryngology》2015,8(4):364-369