夏枯草颗粒联合甲巯咪唑片治疗毒性弥漫性甲状腺肿伴甲状腺功能亢进症患者临床研究

目的：观察夏枯草颗粒联合甲巯咪唑片治疗毒性弥漫性甲状腺肿伴甲状腺功能亢进症患者的疗效及对血清成纤维细胞生长因子21 (FGF21)、促甲状腺素受体抗体（TR-Ab）水平的影响。方法：选择78例毒性弥漫性甲状腺肿伴甲状腺功能亢进患者为研究对象,随机分为对照组与观察组各39例。对照组接受甲巯咪唑片治疗,观察组在对照组基础上联合夏枯草颗粒治疗。比较2组临床疗效,比较2组治疗前后血清游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、促甲状腺素（TSH）及FGF21、TR-Ab水平。结果：治疗前,2组血清FT3、FT4、TSH水平比较,差异无统计学意义（P>0.05）;治疗后,2组血清FT3、FT4水平均降低（P<0.05）,TSH水平升高（P<0.05）,且观察组FT3、FT4水平低于对照组,TSH水平高于对照组（P<0.05）。治疗前,2组血清FGF21、TR-Ab水平比较,差异无统计学意义（P>0.05）;治疗后,2组血清FGF21水平升高（P<0.05）,TR-Ab水平降低（P<0.05）,且观察组FGF21水平高于对照组（P<0.0...     

Reply to Comments on “A Scientometric Analysis of Recent Literature on Arsenic Bioaccumulation and Biotransformation in Marine Ecosystems”

Bulletin of Environmental Contamination and Toxicology - In this letter, we formally replied to the comments on our recently published paper “A scientometric analysis of recent literature on...     

Complete urethral injury in the penile fracture: a case report and literature review

Penile fracture is described as a traumatic rupture of the tunica albuginea caused by blunt injury to the erect penis. It usually occurs as a single rupture of the tunica albuginea in one of two corpora cavernosa; a rupture with urethral injury is an extremely rare condition. Although its diagnosis is usually clinical, ultrasound plays an important role in confirming diagnosis and identifying the site of the injury. Here, we presented a case of penile fracture with complete urethral injury. A 43-year-old male was admitted to the hospital because of trauma to the genital and dysuria following sexual intercourse. After admission, the patient was diagnosed with double penile fracture and complete urethral injury after the physical and B-ultrasound examinations. Emergency surgery to remove the hematoma and repair the urethra was performed. The patient recovered smoothly and was discharged on the third day after operation. After two months’ follow-up, the patient urinated smoothly and achieved an adequate erection without other complications. In this case, consistent with previous studies, emergency surgery for penile fracture is necessary and can preserve the urethral function and sexual function. In addition, there are two lesions in tunica albuginea in this case, so careful search for the penile shaft during the surgery is important to avoid the missed injuries. This report provides evidence of an uncommon and underreported clinical case.     

内皮素与脑梗死

目的 :检测脑梗死病人的内皮素 - 1(ET - 1)水平 ,研究ET - 1与脑梗死的关系。方法 :检测脑梗死病人ET - 1的水平 ,并与正常对照组比较。结果 :脑梗死病人的ET - 1明显高于正常对照组水平 (U =13.45 ,P<0 0 1) ,还发现ET - 1与高血压、糖尿病、高血脂症有一定的关系。结论 :ET - 1的增高是脑梗死发病的内源性危险因素之一 ,ET - 1的增高不但与脑梗死的发病有关而且与脑梗死的发展有关     

口腔颌面鳞癌术前诱导化疗二种方式临床疗效分析

目的 :探讨口腔颌面鳞癌术前诱导化疗二种方式应用的疗效、主要毒副反应差别 ,以及临床适应证。为术前诱导化疗的选择提供临床指导。方法 :本文回顾了 1 0 4例可评价近期疗效的口腔颌面鳞癌术前诱导化疗的病例。其中全身化疗 5 6例 ,颈外动脉插管化疗 48例。结果 :以肿瘤体积缩小 5 0 %以上作为化疗有效指标 ,全身化疗组有效率为 6 4.3%。颈外动脉插管化疗组有效率为79.2 % ,两组总有效率为 71 .2 % (P<0 .0 5 )。全身化疗组的主要毒副反应为胃肠反应、白细胞减少和脱发 ;颈外动脉插管化疗组主要为口腔粘膜溃疡、糜烂及灼痛感。结论 :作为术前诱导的全身化疗较适合于全身状况良好的患者 ,而颈外动脉插管灌注化疗较适合于全身状况稍差、无转移、肿瘤范围不广的患者。     

Clinical Study on Prevention and Treatment of Vaginal Bleeding with Yaoliuan Capsule (药流安胶囊) after Drug-Induced Abortion

ＴｏｔｅｒｍｉｎａｔｅｅａｒｌｙｓｔａｇｅｐｒｅｇｎａｎｃｙｂｙｃｏｍｂｉｎａｔｉｏｎｏｆＭｉｆｅｐｒｉｓｔｏｎｅａｎｄＭｉｓｏｐｒｏｓｔｏｌｉｓｓｕｐｅｒｉｏｒｉｎｈｉｇｈｓｕｃｃｅｓｓｒａｔｅ,ｃｏｎｖｅｎｉｅｎｔｕｓｅａｎｄｌｅｓｓｍｉｓｅｒｙ,ｂｕｔｗｉｔｈｔｈｅｍａｉｎｂａｄｎｅｓｓｏｆｉｎｄｕｃｉｎｇｉｒｒｅｇｕｌａｒｖａｇｉｎａｌｂｌｅｅｄｉｎｇｈａｒｍｆｕｌｔｏｐｓｙｃｈｏｓｏｍａｔｉｃｃｏｎｄｉｔｉｏｎｏｆｐｕｅｒｐｅｒａ．ＦｒｏｍＭａｒｃｈ1993ｔｏＤｅｃｅｍｂｅｒ1995,Ｙａｏ…     

小儿喉乳头状瘤HPV-DNA及体液免疫检测

目的：探讨小儿喉乳头状瘤（ＪＬＰ）人乳头瘤病毒（ＨＰＶ）感染途径及发病机理。方法：采用ＰＣＲ及ＰＣＲ产物斑点杂交技术检测ＪＬＰ组织ＨＰＶ－ＤＮＡ;散射免疫比浊法测定血清Ｉｇ及补体Ｃ３。结果：ＪＬＰ组织ＨＰＶ总感染率为９５％（１９／２０）,其中ＨＰＶ。型为５５％（１１／２０）,ＨＰＶ１１为３０％（６／２０）,ＨＰＶ６＋１１型为１０％（２／２０）;ＪＬＰ患者血清ＩｇＧ、ＩｇＡ、ＩｇＭ、Ｃ３值正常,对照     

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas diagnosed by endoscopic ultrasonography-guided fine-needle aspiration

Undifferentiated carcinoma with osteoclast-like giant cells, also formerly known as osteoclast-like giantcell tumor, is a rare neoplasm of the pancreas and usually diagnosed after pancreatectomy. The presence of non-neoplastic osteoclast-like giant cells is the histological hallmark of this tumor and the diagnosis is usually not difficult on tissue sections. However there have been relatively few reports regarding the cytological features of this type of tumor in literatures.1-4 Here we.     

基因芯片对PMA激活的血管内皮细胞早期反应基因的研究

目的 :用基因芯片研究 PMA激活的血管内皮细胞的早期反应基因 (imm ediate early response gene,ERG)。方法 :以包含 40 96条人类基因的 DNA芯片检测血管内皮细胞受代谢增强剂 PMA(phorbol myristate acetate)激活后早期的基因表达谱 ,并从中筛查出 ERG。结果 :血管内皮细胞受 PMA作用 6 h后 ,17条基因上调 ,11条下调。数据处理聚类分析表明 17条上调基因中多数 (13/ 17)属蛋白质磷酸酶和转录调控因子基因 ,而下调基因中多数 (9/ 11)为细胞分裂相关基因。结论 :证明PMA激活的人血管内皮细胞早期反应基因主要是转录调控因子和蛋白质磷酸酶基因。     

《伤寒论》外治法举隅

汉·张仲景著《伤寒论》中辨证论治体系也包括外治法的内容 ,《伤寒论》中的外治法有针、灸、温覆、熏、导、温粉等治疗方法 ,在临床上用于解表、泻下、和解、清热、温里、固涩、祛湿、预防传变等若干方面。