首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3957973篇
  免费   272569篇
  国内免费   6606篇
耳鼻咽喉   56778篇
儿科学   124595篇
妇产科学   105535篇
基础医学   565730篇
口腔科学   112499篇
临床医学   361918篇
内科学   752519篇
皮肤病学   83527篇
神经病学   320398篇
特种医学   151461篇
外国民族医学   1277篇
外科学   590833篇
综合类   89555篇
现状与发展   13篇
一般理论   1602篇
预防医学   317745篇
眼科学   94119篇
药学   294518篇
  103篇
中国医学   7553篇
肿瘤学   204870篇
  2018年   42316篇
  2017年   32134篇
  2016年   35867篇
  2015年   40343篇
  2014年   57685篇
  2013年   87722篇
  2012年   119301篇
  2011年   126815篇
  2010年   75433篇
  2009年   71397篇
  2008年   119390篇
  2007年   127218篇
  2006年   128435篇
  2005年   124819篇
  2004年   120081篇
  2003年   115547篇
  2002年   113165篇
  2001年   175029篇
  2000年   180536篇
  1999年   152767篇
  1998年   45585篇
  1997年   40440篇
  1996年   40017篇
  1995年   38316篇
  1994年   35720篇
  1993年   33540篇
  1992年   121578篇
  1991年   118603篇
  1990年   115266篇
  1989年   111042篇
  1988年   102914篇
  1987年   101070篇
  1986年   95417篇
  1985年   91690篇
  1984年   69244篇
  1983年   59081篇
  1982年   35789篇
  1981年   32032篇
  1979年   64961篇
  1978年   46068篇
  1977年   38663篇
  1976年   36865篇
  1975年   39078篇
  1974年   47650篇
  1973年   45360篇
  1972年   42868篇
  1971年   40116篇
  1970年   37346篇
  1969年   35148篇
  1968年   32283篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
A Khan  M H Moola  P Cleaton-Jones 《SADJ》2005,60(10):418-421
AIM: To determine trends in fluorosis prevalence at water fluoride levels <0.3, >0.3 to <0.7, and >0.7 to 1.4 ppm from 1980 to 2000. METHODS: A systematic review of 55 published articles identified in a Medline search for peer-reviewed articles on fluorosis published from 1 January 1980 to 31 December 2000. The prevalence recorded with any fluorosis index was pooled and the trends over time were determined in the three water concentration categories. RESULTS: The fluorosis prevalence for the three fluoride categories were 16.7, 27.4 and 32.2 percent, respectively. A 16-fold and a 2-fold increase in fluorosis prevalence compared with reported rates in the 1940s was seen in non-fluoridated (= 0.3 ppm F) and fluoridated (>0.7 to = 1.4 ppm F) areas, respectively. There has been an increase in fluorosis prevalence over time in the three fluoride water concentration categories but linear regression analysis showed that none are significantly different from zero. CONCLUSION: This systematic review concurs with recent reports of an increase in fluorosis prevalence in fluoridated and non-fluoridated communities.  相似文献   
992.
African-American, Hispanic and Native-American/Alaskan Native dental students and professionals are often referred to as underrepresented minorities (URMs) because of their poor representation in the profession compared to their proportion in the U.S. population. Disparities in oral health services may, in part, be attributable to minority and economically disadvantaged patients' lack of confidence in the dental profession's ability to provide care in a culturally sensitive manner. Increasing diversity within the oral health workforce is one way to address this perception. However, an effective remedy will require all oral health professionals to devote additional attention to diversity and cultural competency issues.  相似文献   
993.
994.
995.
Bisphenol-A (BPA) is used to manufacture dental materials such as sealants, fillings and cements. There is evidence of its estrogenic effects on recipients after the placement of dental sealants. Pituitary and especially prolactin (PRL) cells are targets for estrogens.

Objectives

The aim of this research was to determine if BPA eluted from dental resins can alter the proliferation of pituitary cells and PRL cells in the short, medium and long term in a case-control assay.

Methods

Two dental fillings were inserted in the lower incisors of Wistar rats divided into groups sacrificed after one, three, five and seven months. Immunocytochemical treatment was carried out in order to determine proliferating cell nuclear antigen (PCNA) positive cells, PRL-positive cells, PRL- and PCNA-positive cells.

Results

A significant increase of PCNA-positive cells after one (p < 0.05), three (p < 0.01) and five months (p < 0.01) was recorded. PRL-positive cells showed no statistically significant difference between intervened animals and controls. PRL- and PCNA-positive cells manifested a significant increase after five months (p < 0.05). A significant decrease in proliferating cells was observed after seven months (p < 0.05) for PCNA-positive cells and (p < 0.01) for PRL- and PCNA-positive cells.

Conclusion

Low quantities of BPA eluted during mastication can affect immunocytochemical patterns of pituitary cells, increasing cellular proliferation in the short, medium and long term although PRL cell population remained unaffected after dental fillings.  相似文献   
996.

Objective

To analyse the effect of integrated orthodontic treatment, orthognathic surgery and orofacial myofunctional therapy on masseter muscle thickness in patients with class III dentofacial deformity three years after orthognathic surgery.

Design

A longitudinal study was conducted on 13 patients with class III dentofacial deformities, denoted here as group P1 (before surgery) and group P3 (same patients 3 years to 3 years and 8 months after surgery). Fifteen individuals with no changes in facial morphology or dental occlusion were assigned to the control group (CG). Masseter muscle ultrasonography was performed in the resting and biting situations in the three groups. Data were analysed statistically by a mixed-effects linear model considering a level of significance of P < 0.05.

Results

Significantly higher values (P < 0.01) of masseter muscle thickness (cm) were detected in group P3 (right rest: 0.82 ± 0.16, left rest: 0.87 ± 0.21, right bite: 1 ± 0.22, left bite: 1.04 ± 0.28) compared to group P1 (right rest: 0.63 ± 0.19, left rest: 0.64 ± 0.15, right bite: 0.87 ± 0.16, left bite: 0.88 ± 0.14). Between P3 and CG (right rest: 1.02 ± 0.19, left rest: 1 ± 0.19, right bite: 1.18 ± 0.22, left bite: 1.16 ± 0.22) there was a significant difference on the right side of the muscle (P < 0.05) in both situations and on the left side at rest.

Conclusion

The proposed treatment resulted in improved masseter muscle thickness in patients with class III dentofacial deformity.  相似文献   
997.

Background and objective

One way of determining the direction of growth of the mandible is to consider the temporomandibular joint and movement of the mandible as a four-joint gear system, regarding growth then as an extension of the gear system. Our aim was to examine any correlations between the type of biomechanical growth extension and change in the maxilomandibular relation after Class?II therapy.

Subjects and methods

A total of 130?lateral cephalograms??before and after orthodontic treatment??were available from 65?adolescent class?II patients with open bite or deep bite. The two lateral cephalograms from each patient were superimposed on the occlusal plane. Cephalometric values and the vertical base point deviation were determined from biomechanical analyses, together with three distances and three angles.

Results

No correlation between the cephalometric data and distances or angles were observed. Although there were no significant differences in the distances, we did note significant differences in all three angles (p?Conclusion If gear system extension during growth is considered, this can be interpreted as meaning that the occlusal plane of those patients with an initially open bite dropped during treatment, but that it rose in patients with an initially deep bite.  相似文献   
998.
There are few studies on maxillomandibular skeletal alterations. Twenty-one patients with unilateral coronal craniosynostosis were analysed and compared with controls. Landmarks analysed were: sella-nasion-point A and B angles, point A-nasion-point B angle, interincisal angle, angle of superior incisor axis on the sella-nasion plane, lower incisor to mandibular plane angle, Frankfort mandibular plane angle, zygomatic-frontal suture (Z), point on the most concave part of pyramidal apophysis of the upper maxilla (Mx), antegonial incisure (AG), upper (UMT) and lower (LMT) molar teeth. Differences were significant for class II dentoskeletal occlusion (p < 0.0001), mandibular hyperdivergence (p < 0.0001), lingualization of superior incisor (p < 0.005), deviation of inferior interincisal contralateral line to the synostosis (p < 0.0001) in the plagiocephalic population. Compared with contralateral counterpoints, Z (p < 0.05), Mx (p < 0.005) and UMT (p < 0.0005) on the affected side were closer to the midline; AG (p < 0.0005) and LMT (p < 0.05) were further from it. On the frontal plane, Z, Mx, UMT, LMT and AG on the affected side were higher. Vertical and transversal contraction of the jaw of the synostotic side and laterodeviation of the mandibular interincisal line of the contralateral synostotic were clear. The altered position of the glenoid cavity, anteriorized in unilateral coronal craniosynostosis, could be the cause of mandibular dentoskeletal asymmetry.  相似文献   
999.
1000.
The obturating prostheses of the jawbone and the prostheses of rebuilding of the mandible make it possible to restore the losses of substance of the jawbone and of the mandible and to cure the functional and Aesthetic disorders which result from these losses of substance. The success of these prosthetic restorations can be compromised by technical, economic and cultural factors. The principal factors are the importance of the losses of substance, the reduced number of teeth, the poverty of the technical plate, the persistence of certain traditional concepts. The fight against these factors requires the promotion of therapeutic associations in maxillo-facial cancerology, the sensitizing of the populations to the early hospital consultations, the improvement of the technical plate of the prosthesis of the jawbone and the face, the facilitation of the access of the most underprivileged groups to the prosthetic restorations, the promotion of multi-field collaboration, the whole co-operation of the patient throughout the treatment and the follow-up postprothetic.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号