选择性髂内动脉结扎与栓塞对盆腔血供的影响

目的：旨在探讨选择性髂内动脉结扎与栓塞两种方法对盆腔血供的影响。方法：将两组犬在膀胱上动脉分支以下之髂内动脉分别行结扎与栓塞，对比观察两组膀胱创面出血、盆腔动脉造影及盆腔脏器组织学变化，以确定其盆腔脏器的血供情况。结果：①结扎组膀胱创面出血明显大于栓塞组；②结扎组髂内动脉侧支循环建立时间明显早于且数目多于栓塞组；③两组盆腔脏器均未见缺血坏死。结论：栓塞组阻断髂内动脉侧支循环的数目多于结扎组，故对盆腔血供的影响大于结扎组。避免髂内动脉阻断范围过广可减少盆腔脏器缺血坏死的机会。     

Influence of anesthesia on the threshold of pacing-induced ischemia.

Increased myocardial oxygen demand, induced by increased heart rate, may cause myocardial ischemia in the presence of significant coronary artery disease. Alterations in anesthetic depth or technique might put at risk or protect myocardium with compromised blood flow. In 20 dogs with critical left anterior descending coronary artery (LAD) stenosis, atrial pacing rates from 100 to 160 beats/min were achieved, with end-tidal halothane 0.7% (LowH) and 1.1% (HighH), end-tidal isoflurane 1.1% (LowI) and 1.5% (HighI), as well as with continuous fentanyl plus midazolam (FM) infusion anesthesia. Despite significantly different mean arterial and coronary perfusion pressures, rate-pressure product, and left ventricular dP/dtmax, the pacing rate at which systolic shortening decreased below the lower limit of the physiologic response, indicating regional dysfunction, was the same in all investigated anesthesia conditions (LowH: 127 +/- 4 beats/min; HighH: 128 +/- 5 beats/min; LowI: 125 +/- 4 beats/min; HighI: 122 +/- 5 beats/min; FM: 124 +/- 4 beats/min [mean +/- SEM], P greater than 0.05). None of the investigated anesthesia conditions either increased ischemia tolerance or showed a detrimental effect on myocardium with compromised coronary blood flow.     

Acupuncture Treatment of Frequent Urination

Patient Liu （a male office worker of a company in Beijing）, aged 49, paid his first visit on March 10, 2003, with the chief complaint of frequent urination at night for over one year. One year ago, he started to have frequent urination 4-5 times every night, which disturbed his sleep and made him fatigue during the day. Though he tried to drink less water, the above symptoms couldn＇t be alleviated. The condition was accompanied by such symptoms as listlessness, general lassitude,     

红景天胶囊治疗中医虚证100例临床报告

采用随机双盲对照法观察了红景天胶囊与绞股蓝胶囊治疗中医虚证１６０例的临床疗效，结果表明：红景天胶囊治疗明显效率为５４％，总有效率为８７％，与绞股蓝胶囊对照组比较，其疗效有高度统计学意义。红景天胶囊有确切的升高血红蛋白，高密度脂蛋白，超氧化物歧化酶及皮质醇的作用，同时能过氧化脂质，表明该药物具有益气生血，保护细胞免疫损伤，延缓和防止细胞衰老和作用．     

髌骨关节面的应用解剖学研究

本文利用150例髌骨(干燥髌骨100例,福尔马林固定膝关节内的髌骨50例)观测了髌骨关节面和关节软骨的形态及其与股骨内外侧髁关节面在屈膝0～135度范围的对应关系。结果发现中间纵嵴向后突起并由下向上逐渐变凸占100％;内侧纵嵴明显突起者占62％,此时其髌骨内侧部关节面与股骨关节面之间的间隙较大;在膝关节屈曲过程申两关节面接触的顺序为髌骨关节面自下而上、股骨内外侧关节面从前向后相对滑动,伸膝时则相反;髌骨关节面的表面积为1019±20(650～1540)mm~2。并讨论了髌骨关节面的解剖学特点及其临床意义。     

“C”型曲线的中耳声学特性改变与鼓室积液的关系

对40耳声导抗检查为“C”型曲线患耳进行中耳系统共振频率点测试并进行鼓室穿刺抽液,结果表明:共振频率点低于600Hz,患耳鼓室积液阳性率为82.1%,高于600Hz患者鼓室和液阳性率16.7%,提示依据鼓室导抗图和共振频率点测定可初步判断“C”型曲线患耳鼓室积液的可能.     

The Alkaloids of Melodinus acutiflorus. Rhyzicine N-Oxide

From the leaves of MELODINUS ACUTIFLORUS a new alkaloid, rhazicine N-oxide ( 2), and two known compounds, deacetylakuammiline ( 3) and 16- EPI-rhazinaline ( 4) were isolated. The structure of 2 was determined by spectral analysis and chemical correlation with rhazicine ( 1).     

Solution of the discrete Plateau problem

We solve a discrete version of the classic Plateau problem, which asks for a minimal surface spanning a given curve. Our algorithm is based on a network-flow formulation that finds minimal slabs, intuitively corresponding to minimal "surfaces" of prescribed thickness. We let the slab thickness approach zero in order to obtain the desired minimal surface.     

二氧化硅活化巨噬细胞中早期生长反应因子-1及其信号转导通路的研究

目的 探讨早期生长反应因子(Egr-1)及其信号转导在矽肺发生发展中的作用。方法用细胞免疫荧光、原位杂交方法检测二氧化硅(SiO2)刺激后Egr-1的表达定位,用报道质粒及EMSA检测其活性改变;用激酶活性分析法检测si0：刺激巨噬细胞后ERK1／2活性改变,进一步用激酶抑制剂初步探讨SiO2活化Egr-1的信号转导通路。结果SiO2刺激RAW264．7细胞短时间Egr-1核蛋白表达及转录因子明显增加;且在处理后30～60min,Egr-1核蛋白结合活性明显升高(为未处理组的20倍);在刺激后15min ERK1／2活性开始升高,30min达高峰(活性为对照组的29倍)而后渐降至基础水平;进一步用激酶阻断发现,Egr-1 mRNA及蛋白表达均减少。结论SiO2能激活巨噬细胞中Egr-1,且此过程可能由ERK1／2、p38介导,提示SiO2-ERK1／2、p38-Egr-1通路可能在矽肺发生发展过程中起重要作用。