全文获取类型
收费全文 | 1956839篇 |
免费 | 140378篇 |
国内免费 | 7980篇 |
专业分类
耳鼻咽喉 | 28078篇 |
儿科学 | 60446篇 |
妇产科学 | 53225篇 |
基础医学 | 283959篇 |
口腔科学 | 56848篇 |
临床医学 | 172724篇 |
内科学 | 372916篇 |
皮肤病学 | 43858篇 |
神经病学 | 148246篇 |
特种医学 | 76034篇 |
外国民族医学 | 539篇 |
外科学 | 296882篇 |
综合类 | 53835篇 |
现状与发展 | 21篇 |
一般理论 | 585篇 |
预防医学 | 139338篇 |
眼科学 | 46786篇 |
药学 | 150175篇 |
58篇 | |
中国医学 | 9001篇 |
肿瘤学 | 111643篇 |
出版年
2018年 | 20103篇 |
2017年 | 16447篇 |
2016年 | 17850篇 |
2015年 | 20749篇 |
2014年 | 28529篇 |
2013年 | 41120篇 |
2012年 | 54445篇 |
2011年 | 57751篇 |
2010年 | 34785篇 |
2009年 | 32819篇 |
2008年 | 53249篇 |
2007年 | 57341篇 |
2006年 | 57947篇 |
2005年 | 55454篇 |
2004年 | 53131篇 |
2003年 | 51208篇 |
2002年 | 50112篇 |
2001年 | 91334篇 |
2000年 | 93474篇 |
1999年 | 78742篇 |
1998年 | 21601篇 |
1997年 | 19277篇 |
1996年 | 18816篇 |
1995年 | 17819篇 |
1994年 | 16562篇 |
1992年 | 60664篇 |
1991年 | 59418篇 |
1990年 | 58232篇 |
1989年 | 57012篇 |
1988年 | 52787篇 |
1987年 | 51880篇 |
1986年 | 49539篇 |
1985年 | 47027篇 |
1984年 | 34984篇 |
1983年 | 29759篇 |
1982年 | 17493篇 |
1981年 | 15914篇 |
1979年 | 33400篇 |
1978年 | 23840篇 |
1977年 | 20518篇 |
1976年 | 18963篇 |
1975年 | 21508篇 |
1974年 | 25343篇 |
1973年 | 24539篇 |
1972年 | 23338篇 |
1971年 | 21811篇 |
1970年 | 20809篇 |
1969年 | 19762篇 |
1968年 | 18427篇 |
1967年 | 16538篇 |
排序方式: 共有10000条查询结果,搜索用时 171 毫秒
991.
We studied two patients with nonfamilial olivopontocerebellar atrophy with skeletal myoclonus. Palatal or skeletal myoclonus is probably not a coincidental finding but another manifestation of the underlying disease. In both cases, the myoclonus was suppressed by administration of trihexyphenidyl, indicating a cholinergic disorder. 相似文献
992.
Imipenem (N-F-thienamycin) versus netilmicin plus clindamycin. A controlled and randomized comparison in intra-abdominal infections 总被引:1,自引:0,他引:1
下载免费PDF全文
![点击此处可从《Annals of surgery》网站下载免费的PDF全文](/ch/ext_images/free.gif)
In a randomized study the clinical and bacteriologic effectiveness of imipenem was compared with the classical combination of netilmicin with clindamycin in patients who had surgery for an intraperitoneal infection, localized or generalized, with positive bacteriologic findings of the specimen taken at surgery. Excluded were all patients who received other antibiotics before surgery, or who died within 3 days after antibiotic therapy was started. Imipenem was given at a dose of 500 mg t.i.d., clindamycin 600 mg t.i.d., and netilmicin according to serum levels. The diagnoses ranged from postoperative peritonitis, gallbladder empyema, perforated gastroduodenal ulcer, small bowel perforation with and without obstruction, and perforated appendicitis to perforation of the colon. The bacteriologic work-up included examination of the primary specimen (aerobic and anaerobic), the urine, feces, and serologic testing for Candida albicans once or twice a week and after the course of antibiotic therapy. In addition, pH measurements of abscesses and drainage fluids were performed. Ninety-three patients entered the study. Forty-seven patients were treated with imipenem (test group), and 46 patients were treated with the combination therapy (control group). The two groups did not show significant differences in age, sex, diagnostic groups, risk factors, primary bacteriology, and duration of therapy (mean: 6.7 days). Thirty-eight patients (80.9%) treated with imipenem were cured, six patients (12.8%) were improved, and there were three (6.4%) failures. The respective numbers for the control group were 31 (67.4%), 10 (21.7%), and 5 (10.9%). The mean duration of hospitalization was 19 days for the test group and 24.5 days for the control group. There were four wound infections in the test group and 11 wound infections in the control group. Imipenem is at least as effective in the adjuvant therapy of intra-abdominal infections as the combination of netilmicin with clindamycin. 相似文献
993.
Reported in this paper are postoperative results recorded from 120 patients, 3 years after selective proximal vagotomy for uncomplicated duodenal ulcer. There was no intraoperative lethality and no recurrence in 96.7 per cent of all cases, while Visick grades I on II were recorded from 98.2 per cent. Radiologically and gastroscopically detected pathological processes receded soon. Average postoperative reduction in acid secretion was 66.2 per cent in BAO and 46.8 per cent in MAO. Acid values re-increased thereafter, and three years later reduction rates still amounted to 43.7 per cent in BAO and 28.6 per cent in MAO. Indications for proximal gastric vagotomy are discussed in some detail. 相似文献
994.
Ambient light affects pulse oximeters 总被引:1,自引:0,他引:1
995.
N.B.SIMPSON 《The British journal of dermatology》1987,117(1):43-47
Sebum excretion rate was measured by a photometric technique. We demonstrated a high correlation between sebum excretion rates on the left and right sides of the upper back and between back and forehead skin. Sebum excretion rate measurements overlying an open comedone (blackhead) were significantly lower than those obtained from normal skin. This observation demonstrates a functional obstruction to the outflow of sebum and would suggest that the lack of involvement of open comedones in inflammatory acne is not because of the maintenance of a free flow of sebum. 相似文献
996.
997.
A 65-year-old man with spontaneous rupture of the esophagus survived with a direct suture of the esophagus 15 hours after the onset of symptoms. Endoscopic examination of the esophagus was especially of great help in determining the surgical procedure in this patient, and we want to stress the importance of prompt diagnosis and immediate surgery for this disease. 相似文献
998.
999.
Clinical and hormonal effects of chronic gonadotropin-releasing hormone agonist treatment in polycystic ovarian disease 总被引:1,自引:0,他引:1
K Steingold D De Ziegler M Cedars D R Meldrum J K Lu H L Judd R J Chang 《The Journal of clinical endocrinology and metabolism》1987,65(4):773-778
Previously, we reported that short term administration of a highly potent GnRH agonist (GnRHa) for 1 month to patients with polycystic ovarian disease (PCO) resulted in complete suppression of ovarian steroidogenesis without measurable effects on adrenal steroid production. This new study was designed to evaluate the effects of long term GnRHa administration in PCO patients with respect to their hormone secretion patterns and clinical responses. Eight PCO patients and 10 ovulatory women with endometriosis were treated daily with sc injections of [D-His6-(imBzl]),Pro9-NEt]GnRH (GnRHa; 100 micrograms) for 6 months. Their results were compared to hormone values in 8 women who had undergone bilateral oophorectomies. In response to GnRHa, PCO and ovulatory women had rises of serum LH at 1 month, after which it gradually declined to baseline. In both groups FSH secretion was suppressed throughout treatment. Serum estradiol, estrone, progesterone, 17-hydroxyprogesterone, androstenedione, and testosterone levels markedly decreased to values found in oophorectomized women by 1 month and remained low thereafter. In contrast, serum pregnenolone and 17-hydroxypregnenolone were partially suppressed, and dehydroepiandrosterone, dehydroepiandrosterone sulfate, and cortisol levels did not change. Clinically, hyperplastic endometrial histology in three PCO patients reverted to an inactive pattern, and proliferative endometrium in two other PCO patients became inactive in one and did not change in the other. Regression of proliferative endometrial histology occurred in all ovulatory women. Vaginal bleeding occurred in all women studied during the first month of GnRHa administration, after which all but one PCO patient became amenorrheic. Hot flashes were noted by all ovulatory women and by four of eight PCO patients. All PCO patients noted subjective reduction of skin oiliness, and five had decreased hair growth. We conclude that in premenopausal women: 1) chronic GnRHa administration results in apparently complete persistent suppression of ovarian steroid secretion; 2) adrenal steroid secretion is not influenced directly or indirectly; and 3) its use may be helpful in the treatment of endometrial hyperplasia and ovarian androgen excess in women with PCO. 相似文献
1000.