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991.

Objective

To investigate the feasibility, effectiveness, and reproducibility of femtosecond laser (FSL) technology in different corneal cuts.

Design

Experimental study at the Brandon Regional Health Centre.

Participants

Twenty two Human Cadaver eyes donated for research and supplied by the eye bank of Manitoba university.

Methods

In this experimental study, the effectiveness and reproducibility of FSL were investigated in different corneal cuts. The corneas were divided into 5 groups: group I for penetrating keratoplasty; group II for anterior lamellar keratoplasty; group III for corneal pockets for inlays; group IV for intracorneal ring tunnels; and group V for corneal cross-linking pockets. Our primary endpoint was the repeatability of planned versus obtained thickness and diameter of the cuts with FSL. A secondary endpoint was the effectiveness and ease of dissection, rated from 0–4, with 4 being the easiest and 0 the most difficult to dissect.

Results

There was a high correlation between planned and obtained thickness (r = 0.997, p < 0.001) and diameter (r = 0.998, p < 0.001). Both were statistically significant. Linear regression analyses showed that the obtained thickness of corneal cuts in micrometers was significantly predicted by the planned thickness of corneal cuts in micrometers (β = 0.996, t = 56.47, p < 0.001). Likewise, the obtained diameter of corneal cuts in millimeters was significantly predicted by the planned diameter of corneal cuts in millimeters (β = 0.971, t = 70.85, p < 0.001). The surgeons gave 15 out of a total of 22 corneas (68.2%) the maximum score for ease of dissection (Grade 4), where no adhesions were found and the dissection was smooth and steady. Five corneas out of a total of 22 (22.7%) were given a score of 3 of 4 where minor adhesions were found. Two corneas out of a total of 22 (9.1%) were given a score of 2 of 4 where >1 adhesion was found, with some difficulty in separating the cut cornea from the bed. No corneas were given grade 1 or grade 0. No significant differences were obtained for the ease of dissection among the 5 surgery types using Kruskal–Wallis H test (H [4] = 4.971, p > 0.05).

Conclusion

The measured corneal-cut geometry correlated well with laser settings in a variety of full- and partial-thickness FSL corneal patterns, including different depths and diameters. This reproducible efficacy and measurement accuracy of the planned versus obtained cuts could have a favourable result on a variety of corneal surgeries. It also yields a favourable ease of dissection of the cut lenticule from the stromal bed.  相似文献   
992.
Digestive Diseases and Sciences - Histological remission represents a target distinct from endoscopic healing in ulcerative colitis (UC) and seems a better predictor of clinical outcomes. The aim...  相似文献   
993.
Goal: There is limited research on intracerebral hemorrhage in young urban populations. There is reduced access to healthcare and a high prevalence of multiple comorbidities in this vulnerable population. We studied the etiologies and outcomes of spontaneous intracerebral hemorrhage in an urban North Philadelphia cohort aged 50 years old and younger. Materials and methods: A retrospective chart review of subjects 50 years old and younger who presented with spontaneous intracerebral hemorrhage at Temple University Hospital was conducted. A novel scoring system was used to classify the cause of each intracerebral hemorrhage. This system was used to assign a degree of likelihood that hypertension, amyloid angiopathy, tumor, oral anticoagulants, vascular malformations, infrequent causes, or cryptogenic etiologies were present. Aneurysmal subarachnoid hemorrhage was excluded. The prevalence of each risk factor and outcomes were analyzed. Findings: Of the 110 patients in the study, the most common etiology was hypertension (82.7%). There was no statistically significant difference in mortality between patients with multiple possible etiologies for their hemorrhage. Vascular malformations and cavernomas were rare (5.5%). Conclusions: Hypertension was the most common cause of intracerebral hemorrhage in a young urban population. The presence of multiple possible etiologies does not correlate with a worse prognosis of mortality. There is a need for further research into hemorrhagic stroke in young populations.  相似文献   
994.
World Journal of Surgery - In the original version of the article, the last three column headings in Table&nbsp;3 were mislabeled. The original article has been corrected. Following is the...  相似文献   
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Rhabdomyolysis has traditionally been a clinical diagnosis with healthcare providers utilizing historical context, physical exam, and laboratory data to arrive at a diagnosis. However, there are myriad imaging findings that may be corroborative and support the presumptive diagnosis. This paper seeks to review imaging findings associated with rhabdomyolysis using different modalities including radiography, sonography, computed tomography (CT), magnetic resonance imaging (MRI), and bone scintigraphy.  相似文献   
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