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排序方式: 共有9101条查询结果,搜索用时 13 毫秒
91.
Fu YL Hu YX Ling HL Ye ZZ Liang T Zhang MG Liu YK Kang B Luo YJ He SY Lian YJ 《Infectious diseases in obstetrics and gynecology》1994,1(5):235-241
Objective: The objective of this study was to determine whether human papillomavirus (HPV) infections are involved in the development of papillomatosis lesions of the lower female genital tract.Methods: A total of 616 biopsy specimens of genital papillomatous lesions (307 nodular and 309 papular types) from 598 patients were anaylyzed for the presence of HPV DNA sequences by polymerase chain reaction (PCR). These specimens were also examined by histopathological assessment for characteristic HPV-associated cytological changes, by immunohistochemical staining for HPV-associated antigen, and by electron microscopy for the presence of virions.Results: HPV DNA sequences were found in 97.9% (140 of 143 cases) and 1.1% (1 of 91 cases) of the nodular and papular papillomatosis cases tested, respectively. In 18 patients who had both types of papillomatosis lesions, HPV DNA was invariably found only in nodular tissues. HPV-associated antigen, koilocytosis, and virions were found in 53.6% (98 of 183 cases), 70.5% (129 of 183 cases), and 5.9% (5 of 85 cases) of nodular papillomatosis lesions tested, respectively.Conclusions: These data suggest that nodular papillomatosis was closely associated with HPV infection, but that papular papillomatosis of the lower female genital tract may have an etiology other than HPV infection. 相似文献
92.
Human milk oligosaccharides are known to play a role in protection against certain infectious diseases. Previous reports indicate that the content of human milk oligosaccharides varies widely among individuals at term but such information on preterm milk is lacking. After removal of the fat, protein and most of the lactose from non-pooled human milk samples, a total neutral oligosaccharide fraction was isolated by ion-exchange chromatography followed by gel filtration. A Dionex high-performance anion-exchange chromatography system equipped with a pulsed electrometric detector was then employed to measure the levels of ten neutral oligosaccharides in the individual milk samples. Twenty-three milk samples from thirteen mothers who delivered at a mean gestational age of 29.5 (SD 3.1) weeks were collected between days 0 and 33 of lactation, and compared with three samples of term milk from two mothers. The ranges of the total and individual levels of the ten neutral oligosaccharides in preterm milk were similar to those in term milk. Further, as previously described in term milk, preterm milk exhibited a quantitative individual variation. This variation was independent of the gestational age, day of lactation, and postconceptional age. In conclusion, levels of ten neutral oligosaccharides did not differ between preterm and term human milk. 相似文献
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The aim of the present study was to examine the in vivo effect of interleukin (IL)-12 on a murine model of asthma induced by Dermatophagoides pteronyssinus-derived Der p 1 allergen. C57BL/6 mice immunized with Der p 1 allergen adsorbed to alum/pertussis toxin developed a T-helper type 2 (Th2)-dominant immune response characterized by the presence of IgE antibody, airway eosinophil infiltration and increased production of Th2 cytokine. Intraperitoneal injection of IL-12 (1 or 0.1 microg per day) for 5 days (day -1 to +3) simultaneously with each immunization, inhibited the production of IgE and IgG1 antigen-specific antibodies, whereas production of IgG2a was strongly enhanced. In addition, mice receiving both doses of IL-12 showed a strong inhibition of IL-5 but up-regulation of IFN-gamma production by spleen cells stimulated with antigen. Administration of IL-12 also prevented antigen-induced eosinophil infiltration into the bronchoalveolar area in a dose-dependent manner and the primary inflammatory mediator serotonin in bronchoalveolar lavage (BAL) fluids was also reduced significantly. Taken together, the data indicate that IL-12 has a potent immunomodulatory effect on house-dust-mite-induced allergic disorders and may be used as an efficient agent for immunotherapy. 相似文献
97.
ZHONG Xiaoyan Sepp Kaul Astrid Eichler Gunther Bastert Department of Obstetrics Gynecology Tongji Hospital Tongji Medical University Wuhan Laboratory of Oncology Department of Obstetrics Gynaecology Univ 《华中科技大学学报(医学英德文版)》1999,19(3):181-184
RT-PCRamplificationoftumor-asso-ciated(carcinoembryonicantigen)and(or)organ-specific(cytokeratin19)mRNAhasbeenusedmainlyforthedetectionofcircu-latingtumorcellsandmicrometastasesinsolidtumors[1].Originally,theproductofamplificationwasanalyzedbygelelec… 相似文献
98.
LIU Xiaoqing Huang Cuiping Department of Respiratory Diseases Tongji Hospital Tongji Medical University Wuhan 《华中科技大学学报(医学英德文版)》1999,19(3):206-208
Thepathologicalfeaturesofacutelunginjuryinvolvesthelungedemaandlungmi-croatelectasisinducedbythedamageofalveolar-capillarybarrier.Clinicalseverea-cutelunginjurycouldbemanifestedbyres-piratorydistressandrefractoryhypoxia,orso-calledacuterespiratorydis… 相似文献
99.
YANG Zhikuan DU Shuhua Department of Ophthalmology Tongji Hospital Tongji Medical University Wuhan 《华中科技大学学报(医学英德文版)》1999,19(3):246-248
Manyophthalmologicaldiseasesareinvolvedintheretinalthickness.Recentyears,retinalthicknessanalyzer(RTA)hasbeendevelopedtobeusedinvivotomeasuretheposteriorpoleretinalthicknessandtodiagnoseinsuchdiseasesasdiabetesmellitus,glaucoma,maculahole,etc[1].Thes… 相似文献
100.
Demont RG Lephart SM Giraldo JL Giannantonio FP Yuktanandana P Fu FH 《The Journal of sports medicine and physical fitness》1999,39(3):253-258
BACKGROUND: The purpose of this study was to compare the training effects of the Ab-Flex (F), Ab-Roller (R) and standard crunch (C) on EMG production, isometric maximum voluntary contraction (MVC), and isokinetic average peak torque at 30 degrees/sec (ISO) of the abdominal muscles. It was hypothesized that the training devices would have similar value in a strength training program. METHODS: Experimental design: this was a prospective study involving 18 training sessions of progressively increasing repetitions. Setting: Neuromuscular Research Laboratory, University of Pittsburgh. Subjects: thirty-two subjects volunteered for this study, but only 26 completed the training. Each subject participated in recreational activity, but had not performed any abdominal training prior to starting this study. Each subject was randomly assigned to either the control group or one of the treatment groups. Interventions: there were three interventions: two training devices (Ab-Flex and Ab-Roller) and the standard crunch, considered a control group. Measures: the pretest consisted of skin fold measurements (%), EMG activity (V) during the three interventions, and peak torque (Nm) plus EMG during the MVC and ISO tasks. The 18 training sessions over three weeks consisted of three sets of exercise with increasing repetitions from 10 to 20, by 2, every three sessions. The difference in pretest/posttest scores were compared using a One-way ANOVA on the mean differences (Mdiff) for each of: MVC, ISO (peak torque), and EMG for upper rectus (UR), lower rectus (LR), internal oblique (IO), and external oblique (EO). A T-Test was used to detect significance for the body fat measures. RESULTS: Mean differences (Mdiff) were normally distributed about zero for both MVC and ISO (MVC = -0.55, ISO = 4.57). The analysis by group showed no difference (p = 0.596) on the reported means (Nm) -3.16 (C), 5.84 (F) and -4.83 (R). The change associated to the treatment during MVC was only 4% (eta = 0.04). For the ISO the Mdiff (Nm) were 1.39 (C), 13.66 (F) and -2.06 (R) which were not significant (p = 0.127). The Ab-Flex was the only group to have a 95% confidence interval above zero, increasing by an average of 16.5%. There were no significant differences for the EMG activity for Mdiff or between group scores. CONCLUSIONS: No significant differences were found with this study. These results would suggest that using these devices does not add significantly to overall abdominal strength development, or reduction of body fat. A suggestion could be made that certain devices influence muscles differently. 相似文献