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Jose M. Guerra MD PhD Gemma Vilahur MD Antoni Bayés de Luna MD PhD Jose Angel Cabrera MD PhD Manuel Martínez-Sellés MD PhD Guiomar Mendieta MD Adrián Baranchuk MD PhD Damián Sánchez-Quintana MD PhD 《Pacing and clinical electrophysiology : PACE》2020,43(4):427-429
We present the surface electrocardiogram of an open-chest anesthetized healthy adult swine after direct application of ice at the transversus sinus of the pericardium where the Bachmann's region is located. Gradual and transient interatrial block (IAB) in the absence of structural atrial disease is described. This new experimental model demonstrated that IAB is an independent entity from left atrial enlargement. 相似文献
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Damián Pérez-Mazliah Francis M. Ndungu Racheal Aye Jean Langhorne 《Immunological reviews》2020,293(1):57-69
B-cell and antibody responses to Plasmodium spp., the parasite that causes malaria, are critical for control of parasitemia and associated immunopathology. Antibodies also provide protection to reinfection. Long-lasting B-cell memory has been shown to occur in response to Plasmodium spp. in experimental model infections, and in human malaria. However, there are reports that antibody responses to several malaria antigens in young children living with malaria are not similarly long-lived, suggesting a dysfunction in the maintenance of circulating antibodies. Some studies attribute this to the expansion of atypical memory B cells (AMB), which express multiple inhibitory receptors and activation markers, and are hyporesponsive to B-cell receptor (BCR) restimulation in vitro. AMB are also expanded in other chronic infections such as tuberculosis, hepatitis B and C, and HIV, as well as in autoimmunity and old age, highlighting the importance of understanding their role in immunity. Whether AMB are dysfunctional remains controversial, as there are also studies in other infections showing that AMB can produce isotype-switched antibodies and in mouse can contribute to protection against infection. In light of these controversies, we review the most recent literature on either side of the debate and challenge some of the currently held views regarding B-cell responses to Plasmodium infections. 相似文献
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Fernanda Vieira Medina Manoel Dami?o Sousa Neto Jacy Ribeiro Carvalho Junior Heid Sueli Leme dos Santos Melissa Albanese Mezzena Lucas da Fonseca Roberti Garcia 《Journal of applied oral science : revista FOB》2006,14(4):260-263
Objectives:
The aim of this study was to determine the effect of Er:YAG laser irradiation used to clean dentinal walls on the apical sealing of root canals filled with different types of sealers.Background Data:
Laser application to the dentinal walls removed debris, rendering the root canals free of smear layers and leaving the dentinal canaliculi open.Methods:
Sixty-four maxillary canines obtained from laboratory files were instrumented with K-files (Dentsply, Maillefer, Ballaigues, Switzerland) using the crown-down technique, and irrigated with a 0.5% sodium hypochlorite solution. The specimens were divided into two groups of 32 teeth each. In group I, the teeth were instrumented and irrigated with sodium hypochlorite solution, and divided into four subgroups to be sealed with the different materials (Endofill, N-Rickert, Sealapex and Sealer 26). In group II, the root canals were subjected to Er:YAG laser irradiation (200 mJ, 7 Hz and 60 J total energy), followed by root canal sealing as in group I.Results:
The data showed lower levels of apical microleakage in the teeth filled with N-Rickert, Sealapex and Sealer 26 cements than in those sealed with Endofill (p < 0.01). No significant difference in microleakage was observed between teeth irrigated only with 0.5% sodium hypochlorite and those submitted to Er:YAG laser application (p > 0.05).Conclusions:
The Er:YAG laser irradiation applied to the root canal walls was not able to prevent apical microleakage. 相似文献87.
Marco Aurélio Versiani Cássio José Alves de Sousa Antônio Miranda Cruz‐Filho Danyel Elias da Cruz Perez Manoel Damião Sousa‐Neto 《Dental traumatology》2008,24(1):136-139
Horizontal root fractures are uncommon, mainly occurring on the cervical and middle third of the root of permanent upper incisors. The diagnosis is essentially radiographic and requires different healing patterns, depending on some pre- and postinjury factors. The aim of this article was to report the clinical management and different healing types in three cases of horizontal root fractures on permanent dentition. In case 1, the pulp tissue was vital and no treatment was necessary. In case 2, a root canal treatment of the cervical fragment was necessary and in case 3, pulpal necrosis was verified and an apical surgery was performed. 相似文献
88.
Perpiñá Tordera M Belloch Fuster A Ayllón Negrillo E de Diego Damiá A 《Archivos de bronconeumología》2000,36(10):563-568
The aim of this study was to design a new instrument for determining the asthmatic's desire for information as well as his or her active search for it and ability to make decisions about his or her disease. A questionnaire titled Information and Decisions in Asthma (IDEA) was compiled by writing a list of preliminary questions related to each of the three aforementioned aspects. The list was revised and the length reduced vased on the responses and signs of comprehension from a first group of patients. The draft under study then consisted of 36 items in the following subscales: desire for information (DI), active search for information (AS) and decision making (DM) in three scenarios describing stable asthma, mild exacerbation and severe exacerbation. The questionnaire was then administered to 120 adult asthmatic of both sexes whose disease was stable and at different levels of severity. Cronbach alpha coefficients were satisfactory for DI and AS (0.86 and 0.77, respectively) and did not improve with the elimination of any items. Factorial analysis overall for DI and AS (total explained variance = 44.16%) detected two correlated factors (r = 0.34, p < 0.01). The DM subscale contained problems of internal consistency which were solved by removing five items. Factorial analysis for DM then revealed a tri-factorial structure in which each factor adjusted well to each of the scenarios. Analysis of these results indicates that the final version of the IDEA shows very acceptable internal consistency and validity, suggesting that it could be used to assess the aspects it is intended to measure. 相似文献
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