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B. N. S. WALIA S. SINGH R. K. MARWAHA S. R. BHUSNURMATH J. B. DILAWAR 《Journal of gastroenterology and hepatology》1992,7(4):370-373
The cases of three young children (mean age 5.8 years) in whom fulminant hepatic failure and acute intravascular haemolysis were the presenting manifestations of Wilson's disease are reported. Although diagnosis was made ante-mortem and chelation therapy instituted, the course was relentlessly fatal in all three cases. This presentation of Wilson's disease at such a young age is noteworthy. 相似文献
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SINGH Y. N.; ADYA C. M.; KUMAR A.; MALAVIYA A. N. 《Rheumatology (Oxford, England)》1992,31(6):417-419
Adult onset Still's disease was provisionally diagnosed in 31patients from northern India over a period of five years, in27 of whom the diagnosis was subsequently felt to have beenconfirmed. This report describes the clinical characteristicsof these patients along with the different therapeutic measuresused and their response. Adult onset Still's disease shouldbe considered in the differential diagnosis of pyrexiaof unknown origin. KEY WORDS: Still's disease, Pyrexia of unknown origin 相似文献
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Hormone Profiles at High Altitude in Man 总被引:2,自引:0,他引:2
R.C. SAWHNEY P.C. CHHABRA A.S. MALHOTRA T. SINGH S.S. RIAR and R.M. RAI 《Andrologia》1985,17(2):178-184
Altitude induced alterations in circulatory levels of PRL, LH, FSH and testosterone were studied in seven eugonadal men at sea level (SL), during their stay at high altitude (HA, 3500 m) and a week after return to SL. The mean plasma PRL level at SL was 5.83 +/- 1.7 SE ng/ml. On day one and seven of arrival at HA, the PRL values of 7.81 +/- 1.81 and 9.21 +/- 1.64 ng/ml respectively were not significantly different (p greater than 0.05) than the initial SL values. However, on day 18 of stay at HA, PRL levels were significantly increased (p less than 0.01) to 17.68 +/- 1.82 ng/ml and returned to initial SL values within seven days of return to SL. A significant decrease (p less than 0.01) in LH and testosterone was observed on seventh day of stay at HA and the decreased levels were maintained till day 18 of observations. Plasma testosterone returned to the initial SL values within a week of return to SL, whereas LH levels remained significantly lower (p less than 0.01). The FSH levels did not show any significant change during their stay at HA or after return to SL. These observations suggest that exposure to altitude is associated with hyperprolactenemia and an impaired pituitary gonadal function. The decreased levels of LH and testosterone at HA could either be due to hypoxic stress per se or secondary to altitude induced hyperprolactenemia. 相似文献