全文获取类型
收费全文 | 1977篇 |
免费 | 139篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 22篇 |
妇产科学 | 12篇 |
基础医学 | 377篇 |
口腔科学 | 177篇 |
临床医学 | 199篇 |
内科学 | 410篇 |
皮肤病学 | 27篇 |
神经病学 | 115篇 |
特种医学 | 95篇 |
外科学 | 277篇 |
综合类 | 32篇 |
一般理论 | 1篇 |
预防医学 | 173篇 |
眼科学 | 25篇 |
药学 | 86篇 |
中国医学 | 1篇 |
肿瘤学 | 86篇 |
出版年
2021年 | 27篇 |
2018年 | 27篇 |
2016年 | 18篇 |
2015年 | 22篇 |
2014年 | 58篇 |
2013年 | 70篇 |
2012年 | 72篇 |
2011年 | 80篇 |
2010年 | 49篇 |
2009年 | 33篇 |
2008年 | 56篇 |
2007年 | 49篇 |
2006年 | 80篇 |
2005年 | 77篇 |
2004年 | 42篇 |
2003年 | 37篇 |
2002年 | 52篇 |
2001年 | 42篇 |
2000年 | 37篇 |
1999年 | 62篇 |
1998年 | 26篇 |
1997年 | 29篇 |
1996年 | 41篇 |
1995年 | 33篇 |
1994年 | 23篇 |
1993年 | 25篇 |
1992年 | 44篇 |
1991年 | 46篇 |
1990年 | 43篇 |
1989年 | 42篇 |
1988年 | 40篇 |
1987年 | 46篇 |
1986年 | 43篇 |
1985年 | 40篇 |
1984年 | 36篇 |
1983年 | 35篇 |
1982年 | 20篇 |
1981年 | 20篇 |
1980年 | 19篇 |
1979年 | 23篇 |
1978年 | 21篇 |
1976年 | 28篇 |
1975年 | 25篇 |
1974年 | 42篇 |
1973年 | 20篇 |
1971年 | 23篇 |
1970年 | 19篇 |
1969年 | 20篇 |
1967年 | 18篇 |
1966年 | 29篇 |
排序方式: 共有2122条查询结果,搜索用时 31 毫秒
11.
12.
Use of the automatic external defibrillator in the management of out-of-hospital cardiac arrest 总被引:14,自引:0,他引:14
W D Weaver D Hill C E Fahrenbruch M K Copass J S Martin L A Cobb A P Hallstrom 《The New England journal of medicine》1988,319(11):661-666
The automatic external defibrillator is a simple device that can be used by nonprofessional rescuers to treat cardiac arrest. In 1287 consecutive patients with out-of-hospital cardiac arrest, we assessed the results of initial treatment with this device by firefighters who arrived first at the scene, as compared with the results of standard defibrillation administered by paramedics who arrived slightly after the firefighters. Of 276 patients who were initially treated by firefighters using the automatic defibrillator, 84 (30 percent) survived to hospital discharge (expected rate according to a logistic model, 17 percent; P less than 0.001), as compared with 44 (19 percent) of 228 patients when fire-fighters delivered only basic cardiopulmonary resuscitation and the first defibrillation was performed after the arrival of the paramedic team. Few patients with conditions other than ventricular fibrillation survived. In a multivariate analysis of characteristics that influenced survival after ventricular fibrillation, a better survival rate was related to a witnessed collapse (odds ratio, 3.9; 95 percent confidence interval, 2.0 to 7.6), younger age (odds ratio, 1.2; 95 percent confidence interval, 1.0 to 1.4), the presence of "coarse" (higher-amplitude) fibrillation (odds ratio, 4.2; 95 percent confidence interval, 1.6 to 11.0), a shorter response time for paramedics (odds ratio, 1.4; 95 percent confidence interval, 1.0 to 2.1), and initial treatment by firefighters using an automatic external defibrillator (odds ratio, 1.8; 95 percent confidence interval, 1.1 to 2.9). These findings support the widespread use of the automatic external defibrillator as an important part of the treatment of out-of-hospital cardiac arrest, although the overall impact of the use of this device on community survival rates is still uncertain. 相似文献
13.
Hentchel-Franks K Lozano D Eubanks-Tarn V Cobb B Fan L Oster R Sorscher E Clancy JP 《American journal of respiratory cell and molecular biology》2004,31(2):140-146
We investigated cystic fibrosis (CF) transmembrane conductance regulator (CFTR) regulation by A2 adenosine (Ado) receptors and beta2 adrenergic receptors in CFTR-corrected CFBE41o- airway cells and human subjects. CFBE41o- cells stimulated with Ado (10 microM), isoproterenol (Iso, 10 microM), or Ado + Iso (10 microM each) elevated cyclic AMP (cAMP) above control conditions (P < 0.001), with the Iso conditions increasing cAMP approximately 10-fold above that produced by Ado alone (P < 0.001). All agonist conditions had similar effects on short circuit current at 10 and 25 microM, with no further currents produced by subsequent stimulation with forskolin (20 microM). CFTR dependence was demonstrated by glybenclamide block of agonist-stimulated currents. Nasal potential difference studies in normal (n = 50) subjects demonstrated that Ado (10 microM) and Ado + Iso (10 microM each) produced more polarization compared with Iso (10 microM Ado increase = 44%, 10 microM Ado + Iso increase = 52%, P < 0.05 for each condition compared with Iso alone). Studies completed in patients with CF (n = 10, "severe" genotypes) confirmed that Ado-stimulated polarization was CFTR-dependent. Together, these results indicate that Ado is a potent Cl- secretagogue in vivo, with relatively small effects on cAMP levels despite strong effects on CFTR-dependent short circuit current and nasal Cl- transport. These findings support growing evidence indicating a role for Ado regulation of CFTR-dependent Cl- secretion in vivo. 相似文献
14.
15.
Recent advances in the development of transducers for the measurement of vertical and shear forces acting on the plantar surface
of the foot are reviewed. Barefoot and in-shoe discrete and matrix transducers are reviewed in terms of structure, operation,
performance and limitations. Examples of capacitive, piezoelectric, optical, conductive and resistive types of transducer
are presented. Where available, the current clinical status is specified. 相似文献
16.
17.
18.
19.
Use of hybridot assay to screen for BK and JC polyomaviruses in non-immunosuppressed patients. 总被引:3,自引:0,他引:3
下载免费PDF全文
![点击此处可从《Journal of clinical pathology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
J J Cobb C Wickenden M E Snell B Hulme A D Malcolm D V Coleman 《Journal of clinical pathology》1987,40(7):777-781
Urine samples from 50 patients attending a genitourinary outpatient clinic and from 13 renal allograft recipients were investigated for evidence of infection with human BK and JC polyomaviruses using cytology and a new DNA hybridot assay. Forty four per cent of samples from the renal allograft recipients were positive by cytology and 75% by DNA hybridisation, indicating that hybridot assay is more sensitive than cytological screening. BK and JC viral DNA was found in 20% of the patients attending the genitourinary clinic, showing infection with BK virus and JC virus in a group of patients with clinical conditions not normally associated with immunological deficiency-a finding that has not been reported before. 相似文献
20.
Cobb Cory L. Salas-Wright Christopher P. John Rachel Schwartz Seth J. Vaughn Michael Martínez Charles R. Awad Germine Pinedo Miguel Cano Miguel Ángel 《Prevention science》2021,22(3):397-407
Prevention Science - We examined national trends and mental health correlates of discrimination among Latinos in the USA. We used data from two nationally representative surveys based on the... 相似文献