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71.
精神病患者住院期间的体温监测是基础护理的一部分,通过测体温,及时发现病情变化,对发热原因进行分析处理,可有效控制病情.
1 一般资料
我院2009年6月~2010年6月住院治疗的男性患者479例,凡体温超过37.5℃均为调查对象,共40例.按CCMD-3诊断[1],其中精神分裂症20例,心境障碍7例,癔症10例,人格障碍1例,焦虑症1例,强迫症1例.年龄17~72岁,中位年龄39.2岁.所用抗精神病药物有氯氮平、氯丙嗪及其它单用或联合用药. 相似文献
73.
【】目的 探讨总结经显微外科治疗108例破裂前交通动脉瘤围术期的观察与护理。方法 回顾性分析自2009年1月至2013年11月手术治疗108例前交通动脉瘤的临床资料。结果 出院时GOS评分5分56例,4分35例,3分11例,2分3例,1分1例,死亡2例。本组无再出血病例。结论 加强前交通动脉瘤围术期的观察与护理可获得满意预后。 相似文献
74.
目的探讨RNA干扰乏氧诱导因子1α(HIF-1α)对Eca109食管癌细胞放疗敏感性的影响。方法构建干扰HIF-1α质粒pSilencer 2.1 HIF-1α,采用实时荧光定量Real-time PCR、Western Blot方法验证干扰效果,通过MTT、流式细胞仪和克隆形成试验观察RNA干扰HIF-1α对Eca109食管癌细胞的放疗敏感性的影响。结果 RNA干扰可抑制Eca109细胞中HIF-1α和VEGF mRNA转录和蛋白的表达;HIF-1α基因沉默后细胞凋亡增加,且肿瘤细胞对放疗的敏感性增加。结论靶向HIF-1α的shRNA能有效抑制Eca109食管癌细胞的HIF-1α和VEGF基因表达,促进细胞凋亡,增加肿瘤细胞的放疗敏感性。 相似文献
75.
地塞米松对布比卡因诱导小鼠神经元毒性的影响 总被引:1,自引:0,他引:1
Objective To investigate the effect of dexamethasone on the toxicity of bupivacaine in murine neurons.Methods Murine neuroblastoma cell line N2a was obtained from ATCC cell bank (USA). The cells were cultured in 10% fetal cow serum/MEM culture medium and divided into 4 groups voup I control (Con); group II bupivacaine ( Bup); group Ⅲ dexamethasone (Dex) and group IV Dex + Bup. The culture medium contained bupivacaine 900 μmol/L in group Bup and dexamethasone 1 μmol/L in group Dex respectively. In group Dex + Bup ( IV ) Bup was added to the culture medium with a final concentration of 900 μmol/L at 12 h after pretreatment with Dex 1 μmol/L. The cells were inoculated in 24 well plates (0.5 ml in each well, 24 wells in each group) and 10 cm culture dishes (7 ml in each dish, 4 dishes in each group). The release rate of LDH was calculated and the morphology of the cells and nucleus condensation (by Hoechst 3334224 fluorescent staining) was detected at 9 h of incubation in 24 well plates. The mitochondrial transmembrane potential (by JC-1 assay) and phosphorylation of Akt and ERKs (by Western blot) were measured at 5 h of incubation in 24 well plates and in culture dishes respectively. ResultsBupivacaine caused severe damage to the N2a cells as evidenced by increase in LDH release and nucleus condensation (apoptosis), dephosphorylation of Akt and ERKs, decrease in mitochondrial transmembrane potential and severe morphological changes. Dexamethasone pretreatment significantly attenuated bupivacaine-induced neurotoxicity. Conclusion Dexamethasone can protect N2a cells from bupivacaine-induced neurotoxicity through stabilization of mitochondrial transmembrane potential and inhibition of dephosphorylation of Akt and ERKs. 相似文献
76.
目的 探讨温针治疗慢性胃炎的疗效.方法 将86例慢性胃炎患者随机分为对照组西药组(40例),采用西药奥美拉哇胶囊口服疗法,治疗组46例,采用温针疗法.两组分别与治疗前后检测Hp,并对临床疗效作对比分析.结果 胃镜下疗效、Hp清除率、症状改善,治疗组均优于对照组(P<0.05).结论 温针是治疗慢性胃炎的有效方法. 相似文献
77.
约束在词典里的解释是限制管束使之不超越范围。医护人员使用约束的目的是维护病人的安全、防止病人受伤或伤及他人。然而研究亦证实约束亦可能对病人造成生理、心理及社会层面的不良影响甚至致命的伤害。这些变化与护理工作的初衷相违背。任何病人都享有医疗和护理的权利,并且病人享有的医疗权应该是平等的。 相似文献
78.
Objective To investigate the effect of dexamethasone on the toxicity of bupivacaine in murine neurons.Methods Murine neuroblastoma cell line N2a was obtained from ATCC cell bank (USA). The cells were cultured in 10% fetal cow serum/MEM culture medium and divided into 4 groups voup I control (Con); group II bupivacaine ( Bup); group Ⅲ dexamethasone (Dex) and group IV Dex + Bup. The culture medium contained bupivacaine 900 μmol/L in group Bup and dexamethasone 1 μmol/L in group Dex respectively. In group Dex + Bup ( IV ) Bup was added to the culture medium with a final concentration of 900 μmol/L at 12 h after pretreatment with Dex 1 μmol/L. The cells were inoculated in 24 well plates (0.5 ml in each well, 24 wells in each group) and 10 cm culture dishes (7 ml in each dish, 4 dishes in each group). The release rate of LDH was calculated and the morphology of the cells and nucleus condensation (by Hoechst 3334224 fluorescent staining) was detected at 9 h of incubation in 24 well plates. The mitochondrial transmembrane potential (by JC-1 assay) and phosphorylation of Akt and ERKs (by Western blot) were measured at 5 h of incubation in 24 well plates and in culture dishes respectively. ResultsBupivacaine caused severe damage to the N2a cells as evidenced by increase in LDH release and nucleus condensation (apoptosis), dephosphorylation of Akt and ERKs, decrease in mitochondrial transmembrane potential and severe morphological changes. Dexamethasone pretreatment significantly attenuated bupivacaine-induced neurotoxicity. Conclusion Dexamethasone can protect N2a cells from bupivacaine-induced neurotoxicity through stabilization of mitochondrial transmembrane potential and inhibition of dephosphorylation of Akt and ERKs. 相似文献
79.
目的 :观察3种疗法治疗肝硬化并上消化道出血疗效。方法 :甲组38例采用垂体后叶素0.1~0.2U/分持续静脉滴注 ,血压稳定后 ,加用硝酸甘油5~10mg静脉滴注 ;乙组31例采用善得定首剂100μg静脉缓注 ,继之以25~50μg/h持续静脉滴注 ;丙组27例采用三腔二囊管压迫止血。结果 :甲组、乙组有效率分别为71.1 %、83.9 % ,丙组有效率则为59.2 % ,甲组与丙组相比P<0.01 ,乙组与丙组相比P<0.05。结论 :垂体后叶素加硝酸甘油、善得定治疗肝硬化并上消化道出血效果良好。 相似文献
80.
目的:观察桂红鳖甲丸治疗子宫肌瘤的疗效。方法:136例患者随机分为两组,治疗组68例,口服桂红鳖甲丸;对照组68例,口服安慰剂。两组均3月为1个疗程。结果:治疗组有效率为47.1%,明显优于对照组(26.5%),P〈0.05;治疗组中医证候疗效有效率为85.3%,明显优于对照组(22.1%),P〈0.01。结论:桂红鳖甲丸治疗气滞血瘀型子宫肌瘤疗效显著。 相似文献