艾滋病与真菌感染

人类免疫缺陷病毒(HIV)特异性侵犯CD_4~+细胞,使机体免疫功能严重受损,导致各种机会性感染,其中真菌感染相     

关于鼠患船舶集中趋势的初步探讨

1990年1月至1995年12月对停泊在烟台港国际航行的2841艘各类船舶鼠患情况进行综合分析，发现有鼠患的船舶占被检查船舶的12．81％；并通过对船舶国籍、船龄、大小、种类及其在口岸类型不同的分析，发现鼠患船舶有集中于国内船、老龄船、小型船、渔船以及停泊在二类港口船舶的趋势。     

蕈样肉芽肿凝集素免疫病理研究

作者用生物素-抗生物素-过氧化物酶复合物(ABC)法对17例蕈样肉芽肿(MF)的12种凝集素受体进行了免疫组化观察。10例扁平苔藓(LP)作为对照组。PNA、DBA、SBA、BSA、PSA、SJA 和 UEA—1七种凝集素受体在 MF 及 LP 均未见表达。RCA—1、WGA、Con—A、LcA 及 PHA 在 MF 及 LP 则有表达。结果提示:MF 和 LP 中淋巴细胞凝集素受体表达有所不同;但在分化程度上都处于成熟阶段。     

银屑病性关节炎的内用药物治疗

近年来文献作者治疗银屑病性关节炎的首选药物主要集中在柳氮磺胺吡啶、低剂量甲氨蝶呤及环孢菌素A三种药物上。认为对患者的预后及提高生活质量有重要意义。对传统的非类固醇抗炎剂治疗银屑病性关节炎的观念发生重大变化，其一是该类药物可以增加花生四烯酸产生，使银属病加重；其二是控制关节损害疗效不佳。同时也不主张糖皮质激素应用，因为可能使银屑病加重或使其顽固难治。生物技术疗法是近来研究的热点，远期的疗效正在进一步的观察中.     

重组生长激素对严重感染后蛋白代谢影响的实验研究

本文旨在探讨重组生长激素对腹腔严重感染后蛋白质代谢的影响及其作用机制。作者以大鼠讯肠结扎穿孔复制严重感染模，并将其分为治疗组和感组，分别于术后给予生长激素和生理盐水，进行观察研究。     

银屑病与β趋化因子

银屑病的病因不明 ,免疫 -炎症机制正日益受到重视。近年来人们发现作为趋化因子家族中最大的一类 ,β 趋化因子在银屑病发病机制中发挥重要作用。它们在银屑病患者中表达异常 ,并且在治疗前后会发生相应的变化     

Progress of experimental study on treatment of psoriasis by Chinese medicinal monomer and single or compound recipe in Chinese materia medica

Psoriasis is a common,chronic,recurrent inflammatory skin disorder whose etiology is still unknown.It is believed that a multiple-gene inheritance is involved and it also involves various factors such as immunity,inflammation,cell proliferation,apoptosis,neural media,etc.Since cytokines are key mediators in inflammation,a number of Chinese medicines(CMs)have been reported to have certain antagonist effects on pro-inflammatory cytokines such as tumor necrosis factor-α(TNF-α),platelet active factor(PAF)and interleukin-8(IL-8).Some researches on CMs have made significant breakthroughs in psoriasis by intervening with cytokines.Abnormalities with keratinocyte proliferation and apoptosis are considered to be present in patients with psoriasis and a number of studies show that the mechanism of CMs on psoriasis may be through the inhibition of the keratinocyte proliferation and induction of apoptosis.Other studies also show that the inhibition of fibroblast-secreted cytokines could regulate keratinocyte proliferation and differentiation and reduce the level of Calcitonin gene-related peptide(CGRP)in plasma and in lesions so as to slow down the process of inflammation and proliferation in psoriasis.The most commonly used models for psoriasis are the scaled tails or the vaginal epithelium of mice in China.They were used to observe the histopathological changes after the model mice were treated with CMs with the inhibition on the mitosis of vaginal epithelium or promotion of granular layer in rat tail taken as the indices of clinical efficacy.A variety of signs occur in psoriasis patients with TCM blood-stasis syndrome type and the effect of CMs in activating blood circulation to remove blood stasis on psoriasis suggested that the mechanism of CMs may be partially correlated to hemorrheology and microcirculation.Along with the continuous development of the biosciences,some TCM theories for psoriasis have been confirmed by laboratory studies.However,the exploration into traditional Chinese medicines'biomechanics in psoriasis and the therapeutic mechanism of CMs by integrative medicine still requires further studies.     

连云港地区白蚁危害频发的原因及对策

通过对连云港地区白蚁危害情况的调查研究发现,近年来,连云港地区白蚁危害有逐年增加的趋势,本文主要阐述了连云港地区白蚁频发的原因,为以后制定具体的防治措施提供科学依据。