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Objective:To investigate the role and the clinical significance of anti-zona pellucidaantibody (AzpAb) and tumor necrosis factor-α(TNF-α),γ-interferon(IFN-γ) and inter-leukin-2 (IL-2) in sera from patients with premature ovarian failure (POF).Methods: The AzpAb in the serum of POF patient was analyzed by means ofELISA. The levels of TNF-α, IL-2 and IFN-γ in the serum were determined by meansof radioimmunoassay (RIA).Results:The level of serum AzpAb in the POF patients was significantly higher thanthat of the normal controls(P<0.001). The levels of TNF-α and IL-2 were significantlyreduced (P<0. 001), and the level of IFN-γ was significantly elevated (P<0.01). Thelevels of above three cytokines in AzpAb positive group were significantly higher thanthose of the negative group in POF patients.Conclusion: This study suggested that AzpAb, TNF-α, IFN-γ and IL-2 might playimportant roles in the pathogenesis of autoimmune POF. 相似文献
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目的:观察地红霉素治疗非淋菌性尿道(宫颈)炎的临床效果。方法:对确诊的55例非淋菌性尿道(宫颈)炎患者,口服地红霉素肠溶胶囊500mg,每天1次,连服10天,停药5天后复查,观察疗效。结果:55例患者中,痊愈43例(78.2%),显效8例(14.5%),有效2例(3.6%),无效2例(3.6%),总有效率为92.7%、结论:地红霉素对非淋性尿道(宫颈)炎治疗效果确切,且未发现明显的不良反应,可供临床医生选用。 相似文献
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为了更好地贯彻落实国家、自治区农村卫生工作的决定,认真总结我州新型农村合作医疗(简称新农合)的经验和教训.推动我州合作医疗工作的有序开展.根据州政协2005年度工作计划.在政协领导的带领下.教科文委员会部分委员会同州卫生、财政等部门,对我州焉耆、若羌2县新农合工作进行了调研。调研工作围绕着新农合由政府举办、商业保险两种模式的利弊.听取了两县政府关于新农合工作情况的汇报,召开了卫生、财政、定点医疗机构、县乡两级合管办等部门人员和农牧民参保人员座谈会.广泛征求了对新农合的意见和建议.并实地察看了县乡两级定点医疗机构.现将调研情况报告如下。 相似文献
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反复自然流产(滑胎)是全世界共同关注的疑难病症,也是妇科常见病之一,其发病率占育龄妇女的0.4%~0.8%。反复流产中有60%是不明原因的,称为不明原因复发性流产(unexplained recurrent spontaneous abortion,URSA),其病因复杂,容易复发。有研究报道:连续自然流产1、2、3次后,再发生妊娠流产的风险率分别为13%、37%、84%[1]。反复自然流产常见病因很多,包括免疫因素、遗传性因素、内分泌因素、解剖因素、感染因素、微量元素、环境因素、心理和应激因素等。 相似文献