胱氨酸蛋白酶抑制剂C评价肾脏滤过功能的价值探讨

目的 探讨血清胱氨酸蛋白酶抑制剂C(Cytatin C)在评价肾脏滤过功能方面的价值.方法 用颗粒增强散射免疫比浊法检测55例肾脏内科病人Cytatin C的浓度,同时测定其血清尿素氮、肌酐浓度及其内生肌酐清除率,作相类分析比较.结果 Cytatin C、尿素氮、肌酐与内生肌酐清除率之间呈高度相关.结论 Cytatin C能够替代操作复杂的内生肌酐清除率来判断肾小球的滤过功能.     

病毒性肝炎患者SCL-90的相关调查

为探讨病毒性肝炎对患者心理健康状况的影响,用SCL-90(Symptom Checklist 90,SCL-90)量表对142例病毒性肝炎患者进行问卷调查.对象与方法以1999～2000年我院住院病人中确诊的142例病毒性肝炎病人为调查对象,并符合以下条件:年龄16～60岁;近一周未服用抗精神病药物;初中以上学历;既往无精神病史现无合并其他心身疾病史;愿意参加该心理测验;病毒性肝炎中不包括重症肝炎、肝硬化.男107例,女35例,平均年龄(31.72±10.17)岁;其中甲肝9例,乙肝85例、丙肝6例,戊肝4例,病原学未定者33例,乙肝合并甲肝2例,乙肝合并戊肝3例,均符合1995年中华传染病会议(北京)制定标准;已婚87人,未婚54人,离异1人;文化程度:博士后1人,硕士1人,大学(含大专)以上63人,高中(含中专)46人,初中31人;职业:干部27人,职员8人,教师12人,学生16人,工程师6人,翻译1人,医护人员4人,财会7人,公检法3人,商业服务4人,司机5人,工人32人,农民3人,个体1人,下岗人员13人.发出调查表150份,回收合格答卷142份.     

改良显微小梁切除术治疗葡萄膜炎继发性青光眼

Objective To investigate the effect of trabeculectomy combined with segmental iridectomy, mitomycin C (MMC) and viscoelastic agents usage on the treatment of glaucoma secondary in uveitis. Methods According to the age, degree of inflammation and the condition of Tenon capsule of patients, differ-ent concentration of MMC (0.25-0.33 mg/ml) was used during the operation, with separation of the anterior and posterior synechia, resection of pupillary organization membrane using viscoelastic agents. Segmental iridec-tomy and releasable sutures were also performed on the patients. The visual acuity of preoperation and postoper-ation, intraocular pressure, inflammation and the complication were record. Results Forty-two eyes of 38 cases with glaucoma secondary in uveitis were studied, the mean follow-up time was (12.01±3.56) months. The postoperative visual acuity improved in 14 eyes, didn't change in 28 eyes. The postoperative inflammation of anterior chamber disappeared in 35 eyes, relieved in 7 eyes. And the average postoperative intraocular pres-sure (15.20± 4.64) mmHg was significantly lower than the preoperative intraocular pressure (38.37±12.93) mmHg (t = 8.255, P = 0.000). The total success rate was 92.9%. There were no severe complication. Conclusion Trabeculeetomy combined with MMC, viscoelastic agents usage, separation of anterior and poste-rior syneehia, segmental iridectomy and releasable suture could increase the success rate of operation on pa tients with glaucoma secondary in uveitis, decrease the complication and inflammation reaction of operation, and the recurrence of uveitis.     

改良显微小梁切除术治疗葡萄膜炎继发性青光眼

Objective To investigate the effect of trabeculectomy combined with segmental iridectomy, mitomycin C (MMC) and viscoelastic agents usage on the treatment of glaucoma secondary in uveitis. Methods According to the age, degree of inflammation and the condition of Tenon capsule of patients, differ-ent concentration of MMC (0.25-0.33 mg/ml) was used during the operation, with separation of the anterior and posterior synechia, resection of pupillary organization membrane using viscoelastic agents. Segmental iridec-tomy and releasable sutures were also performed on the patients. The visual acuity of preoperation and postoper-ation, intraocular pressure, inflammation and the complication were record. Results Forty-two eyes of 38 cases with glaucoma secondary in uveitis were studied, the mean follow-up time was (12.01±3.56) months. The postoperative visual acuity improved in 14 eyes, didn't change in 28 eyes. The postoperative inflammation of anterior chamber disappeared in 35 eyes, relieved in 7 eyes. And the average postoperative intraocular pres-sure (15.20± 4.64) mmHg was significantly lower than the preoperative intraocular pressure (38.37±12.93) mmHg (t = 8.255, P = 0.000). The total success rate was 92.9%. There were no severe complication. Conclusion Trabeculeetomy combined with MMC, viscoelastic agents usage, separation of anterior and poste-rior syneehia, segmental iridectomy and releasable suture could increase the success rate of operation on pa tients with glaucoma secondary in uveitis, decrease the complication and inflammation reaction of operation, and the recurrence of uveitis.     

青光眼睫状体炎综合征反复发作对视网膜神经纤维层厚度及视野影响的研究

目的 观察青光眼睫状体炎综合征反复发作是否会对视网膜神经纤维层厚度及视野产生影响.方法 收集2014年7月—2016年7月在我院诊断为青光眼睫状体炎综合征且发作2次的患者16例,将其发病眼作为发作眼组,对侧眼列为对侧眼组,选取在我院健康体检者为正常对照组.在第1次及第2次发作眼压控制后3 d内及满3个月时均记录一般资料、眼部常规检查,并运用自动视野计行标准全视野检查,眼科相干光断层扫描仪行以视乳头为中心1.73 mm半径内不同象限视网膜神经纤维层厚度检查.结果 各组不同时间点视网膜神经纤维层厚度的比较差异无统计学意义(P>0.05);16例患者在反复发作后出现视野缺损和出现鼻侧阶梯或者旁中心暗点的患者均为0例(0眼).结论 青光眼睫状体炎综合征反复发作对视网膜神经纤维层厚度的改变不明显,但可能出现视野损害.     

血清脂肪酶检测在肾功能衰竭中的临床意义

目的探讨血清脂肪酶（LPS）与急、慢性肾功能衰竭之间的联系。方法以速率比浊法测定11例急性肾功能衰竭（ARF）、24例慢性肾功能衰竭（CRF）、17例肾病、22例肾炎、31例肾结石患者及30名健康体检者血清LPS水平并作比较。结果ARF、CRF组血清LPS水平明显高于正常对照组、肾结石组、肾炎组及肾病组（P〈0．05,P〈0．01）,CRF组血清LPS水平高于ARF组（P〈0．05）,而其他4组间LPS水平差异均无统计学意义（P〉0．05）。结论LPS是一种反映ARF、CRF较好的血清酶学指标。关键词：脂肪酶;肾功能衰竭     

防疟大事不可疏忽

正2015年10月5日,瑞典卡罗琳医学院在斯德哥尔摩宣布,中国女性药学家、中国中医科学院中药研究所首席研究员屠呦呦因为发现了抗疟药物青蒿素而获2015年诺贝尔生理学或医学奖。这是中国科学家在中国本土进行的科学研究而首次获诺贝尔科学奖,是中国医学界迄今为止获得的最高奖项。青蒿素能有效降低疟疾患者的死亡率。至此,疟疾再度出现在公众的视野中。     

国外原装与国产比色杯在ACL TOP血凝仪应用中的一致性分析

目的探讨国外原装与国产比色杯在ACL TOP血凝仪应用中的一致性。方法选取24份临床血凝检测标本,分别用原装配套的比色杯和国产比色杯进行检测,对检测结果进行Bland-Altman统计分析。结果 PT、FIB、APTT、TT检测结果在一致性界限外的概率很低,在一致性界限内的最大差值可接受。结论国产和国外原装比色杯一致性良好,在ACL TOP血凝仪中可用国产比色杯取代原装产品。