急性细菌性结膜炎的防治

结膜炎病因极其复杂,如细菌性、病毒性、物理、化学性,以及全身过敏状态均可引起此病。平时常见的急性细菌性结膜炎是流行性眼科疾病,通常人们称为“红眼睛”或“火眼”,常在春夏暖和季节最易发病。1　病因及症状急性细菌性结膜炎的主要症状是起病急,常双眼累及,有异物感,烧灼感、痒、怕光、流泪、眼睑水肿、结膜呈鲜红色或火红色充血,分泌物多,有时可附着角膜表面,上下睫相互粘连,病情一般在3～4天达到高潮,随后症状逐渐减轻,二周消退。儿童患者在睑结膜上可有假膜形成,但一般无视力障碍,此病的致病菌为肺炎双球菌、流行性感冒杆菌,是细菌…     

继发不孕与生殖道感染的临床相关性分析

目的探讨继发不孕妇女生殖道感染的情况及与输卵管炎症的相关性。方法对985例继发不孕妇女的临床资料进行回顾性分析,采用碘海醇注射液进行子宫输卵管造影,根据输卵管通畅情况分为3组,即输卵管完全阻塞组（A组）、部分阻塞组（B组）和通畅组（C组）,取宫颈分泌物进行生殖道病原体（解脲支原体、沙眼衣原体、人型支原体）检测,并进行临床分析。结果在继发不孕的985例患者中,感染率依次为解脲支原体25．48％（251／985）、沙眼衣原体5．89％（58／985）、人型支原体2．44％（24／985）。其中解脲支原体感染者输卵管通畅组与完全阻塞组及部分阻塞组均有统计学差异（Pearsonχ2=40．629,P〈0．05;沙眼衣原体感染者输卵管通畅组与完全阻塞组有统计学差异（Pearsonχ2=6．898,P〈0．05）;人型支原体感染者输卵管通畅与否均无统计学意义（eearsonχ2=2．897,P〉0．05）。结论在继发不孕妇女中,应重视对解脲支原体、沙眼衣原体的检测,从而降低输卵管性生不孕的发生率。     

地西他滨联合安罗替尼对多发性骨髓瘤细胞增殖和凋亡的影响

目的：探讨地西他滨联合安罗替尼治疗多发性骨髓瘤（MM）的生物学效应及可能的机制。方法：分别应用不同浓度的地西他滨、安罗替尼以及地西他滨+安罗替尼处理MM细胞系和原代细胞，CCK-8法检测两药对细胞增殖的影响，并计算协同指数，流式细胞仪检测细胞凋亡率，Western blot检测药物对c-Myc蛋白的影响。结果：地西他滨和安罗替尼单药均能有效地抑制MM细胞系NCI-H929和RPMI-8226的增殖，并且诱导细胞凋亡；两药联合组抑制细胞增殖和诱导凋亡的效果明显强于单药组。两药联合在原代MM患者细胞中也显示出较强的细胞毒性。地西他滨和安罗替尼能够下调MM细胞中c-Myc蛋白的水平，并且联合用药组的c-Myc水平最低。结论：地西他滨联合安罗替尼能够有效地抑制MM细胞的增殖并且诱导其凋亡，这为地西他滨联合安罗替尼治疗MM提供了一定的实验基础。     

妇科癌症化疗后的辨证施治

癌症病人目前在我国乃至世界发病率高，死亡快。据统计全世界每年死亡于癌症的人数约700万，其中中国约100万。因此癌症的防治已成为医学界所关注的重要课题。在治疗中，西医治疗的三大法宝，手术、放疗和化疗，但是对于放疗、化疗而产生的毒副作用较大，西医束手无策，难以治愈，如妇科卵巢癌、子宫癌、乳腺癌等切除术后采用化疗过程中，白细胞及全血细胞减少是较为普遍的临床副反应。由于贫血或全血细胞减少，迫使不少患者中断治疗。所以患者往往求中医治疗，认为无痛苦对机体无伤害。对此，我们通过几十年的临床实践与体会，认为中医中药有着十分肯定的疗效及发展研究前景。     

福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

高频彩超在诊断小儿急性肠系膜淋巴结炎中的应用价值

目的探讨高频彩超在诊断小儿急性肠系膜淋巴结炎中的应用价值。方法用高频彩超对120例急性肠系膜淋巴结炎患儿进行检查。结果右侧腹及脐周均见多个不同程度肿大的淋巴结,经治疗后复查肿大淋巴结不同程度缩小。结论高频彩超诊断小儿急性肠系膜淋巴结炎具有很高的应用价值。     

亚临床甲状腺功能减退症与自然流产史的关系探讨

目的探讨亚临床甲状腺功能减退症（亚甲减）与自然流产史的相关性及治疗亚甲减对降低自然流产率的作用。方法2011年1月—2012年12月在浙江省绍兴市妇幼保健院生殖中心就诊的210例早孕期妇女作为研究对象,其中复发性流产史患者50例作为A组,有1次自然流产史患者80例为B组,无自然流产史患者80例为C组。用电化学发光法检测促甲状腺素（TSH）、游离甲状腺素（FT4）。用左旋甲状腺素片（优甲乐）进行治疗。结果A组、B组、C组患者的年龄分别为（28．5±4．7）岁、（27．9±3．9）岁和（29．2±4．1）岁,3组年龄均符合正态分布,差异无统计学意义（x2=2．246,P〉0．05）。亚甲减患病率A组为26．00％,B组为18．75％,C组为5．00％。A组和B组亚甲减患病率差异无统计学意义,A组和B组亚甲减患病率均高于C组,差异有统计学意义（Pearson x2=11．740,P〈0．05）。经过左旋甲状腺素片（优甲乐）治疗后,A组流产率为23．08％,B组13．33％,而C组无1例流产。C组流产率明显低于A组和B组,提示亚甲减与妊娠不良结局具有一定相关性。结论亚甲减与自然流产有明显相关性,但亚甲减经过左旋甲状腺素治疗后可降低再次流产的发生率。     

心复平治疗冠心病合并频繁室性早搏的临床研究

目的运用中药自制汤剂“心复平”进行冠心病合并频繁室性早搏临床疗效的观察。方法按入选标准选取病例共80例，随机分成治疗组（A组）和对照组（B组）两组，各40例。其中A组服用“心复平”日煎1剂，2次／d；B组服用心律平100mg，3次／d，口服，同时服用长效异乐定片50mg，1次／d，口服。结果（1）临床疗效：A组为85％，13组为90％，P〉0．05。（2）24h动态心电图疗效：A组为87．50％，B组为92．50％，P〉0．05。（3）毒副反应：A、B两组在治疗前后均做三大常规、肝肾功能检查，差异无显著性（P〉0．05）。A组无一例药物和胃肠反应；B组在治疗期间有1例胃肠反应，3例肝功能指标发生异常，且早期均有不同程度的头痛反应。结论心复平治疗冠心病合并频繁室性早搏疗效显著，有一定的临床意义。