福建省龙岩市城乡居民碘营养水平与甲状腺功能现状研究

目的了解龙岩市城乡居民碘营养水平和甲状腺功能,为因地制宜、科学补碘提供参考依据。方法选择龙岩市中心城区和漳平市双洋镇园当村分别作为城市和农村调查点,B超法检测儿童甲状腺容积,砷铈催化分光光度法检测尿碘含量,直接滴定法检测盐碘含量,直接化学发光免疫分析法检测甲状腺功能指标,率、中位数的比较分别用χ2检验和Median检验,P<0.05为差异有统计学意义。结果 8～10岁儿童甲状腺容积中位数为2.54ml,肿大率为1.67%(4/239),城市和农村差异无统计学意义(P>0.05)。居民户碘盐覆盖率为100%(403/403),合格碘盐食用率为95.29%(384/403)。儿童、成人、孕妇和哺乳期妇女尿碘中位数分别为332.3、233.9、162.3、152.6μg/L,城市和农村地区儿童、农村地区成人存在碘摄入过量,其他人群碘营养适宜。甲状腺功能异常率为18.52%(115/621),城市低FT4血症的比率高于农村(P<0.01),而农村亚甲减的比率高于城市(P<0.05)。结论加强碘营养水平和甲状腺功能监测;适时调整食盐加碘水平,以满足不同人群碘营养需要。     

血脂改变与2型糖尿病血管并发症的关系

目的研究2型糖尿病和2型糖尿病合并血管并发症患者血脂水平的变化,探讨血脂异常在2型糖尿病血管并发症发生中的作用。方法测定50例2型精尿病无血管并发症患者,56例2型糖尿病伴血管并发症患者及53例正常对照者系列血脂、空腹血糖水平。结果①糖尿病组与对照组比较,血清甘油三酯(TG)、胆固醇(TC)、低密度脂蛋白(LDL)、载脂蛋白B(Apo-B100)显著升高(P＜0.05或0.01),高密度脂蛋白(HDL)显著降低(P＜0.05或0.01)。②2型糖尿病伴血管并发症组与无血管并发症组比较,TG、TC、LDL、Apo-B100显著升高(P＜0.01),HDL显著降低(P＜0.01)。③空腹血糖(FBS)与TG、TC、LDL、Apo-B100呈正相关(r=0.32、0.22、0.28、0.21,P＜0.05),与HDL呈负相关(r=-0.26,P＜0.05),与Apo-A1无相关性(r=0.076,P＞0.05)。结论空腹血糖水平与血脂异常程度相关,脂代谢障碍是2型糖尿病血管并发症的重要因素。     

肺癌患者贫血60例临床观察

恶性肿瘤是慢性贫血的原因之一。为了解肺癌的贫血特点，于１９９６年２月至１９９８年１０月，我们对６０例肺癌患者的血红蛋白（Ｈｂ）、红细胞（ＲＢＣ）计数等变化进行了研究。结果表明继发于肺癌的贫血与多种因素有关，是一种进行性的、不易纠正的贫血，是肺癌预后不良的一个因素。     

氟伐他汀治疗早期糖尿病肾病疗效分析

目的　探讨氟伐他汀治疗糖尿病肾病 (DN)的疗效及其抗炎机制。方法　选择 2 0 0 0 - 0 2～ 2 0 0 3- 0 6广东省东莞市人民医院门诊及住院的 14 0例早期DN患者随机分为治疗组和对照组。对照组给予常规治疗 ,治疗组每晚加服氟伐他汀 4 0mg。比较两组治疗前及治疗后 3、6、9个月的尿白蛋白排泄率 (UAER)、血肌酐 (Scr)和反应蛋白 (CRP)等指标。结果　治疗组UAER和Scr下降比对照组明显 (P <0 0 5 ,P <0 0 1) ,起效更快 (早 3个月 ) ;治疗组CRP明显下降 (P <0 0 5 ,P <0 0 1) ,而对照组CRP下降不明显 (P >0 0 5 )。而且 ,对两组中血脂正常的DN患者进行比较分析也得出类似的结果。结论　氟伐他汀因降低CRP的抗炎效应而减轻微量白蛋白尿和改善肾功能 ,该作用不依赖氟伐他汀的降血脂效应     

福建省龙岩市碘缺乏病病情监测结果分析

目的 了解福建省龙岩市碘缺乏病病情现状,评价防治措施效果,为制订防治策略提供依据.方法 2006和2007年期间,在福建省龙岩市7个县(市、区),每个县(市、区)按容量比例概率抽样法(PPS)确定30所小学,每所小学抽取40名8～10岁学生,进行甲状腺触诊检查,同时抽取7名学生采集尿样和家中盐样,进行尿碘及盐碘测定,计算甲状腺肿大率、尿碘中位数、合格碘盐食用率、碘盐覆盖率、碘盐合格率和非碘盐率.结果龙岩市8～10岁儿童甲状腺肿大率为0.94%(79/8438),尿碘中位数为259.12μg/L,合格碘盐食用率为97.86%(1462/1494),碘盐覆盖率为99.46%(1486/1494),碘盐合格率为98.38%(1462/1486),非碘盐率为0.54%(8/1494).结论 龙岩市的碘缺乏病防治工作达到国家消除碘缺乏病标准.     

百草枯中毒与肺损害11例

目的探讨百草枯中毒对肺损害的临床特点与治疗方法.方法分析了11例百草枯中毒患者的临床资料,并对其中2例患者作了肺活检.结果中毒量3g以上的8例患者同时出现多器官损害(主要是消化道、肝、肾、心、肺),尤以肺损害严重.在第一周内,其中5例动脉血氧分压(PaO2)为(4.9±0.5)kPa、动脉血二氧化碳分压(PaCO2)为(2.8±1.4)kPa,氧合指数(PaO2/FiO2)为(14.7±3.1)kPa,X线胸片表现为双肺弥漫性斑片状影,临床上表现为急性呼吸窘迫综合征(ARDS).后期1例出现气胸,2例肺组织检查经病理证实为双肺弥漫性肺间质纤维化.8例死亡均与呼吸衰竭有关.结论百草枯中毒致肺损害,早期临床上以ARDS为主要表现,后期可出现肺间质纤维化.     

龙岩市大学生精神卫生现况调查

[目的]了解大学生精神卫生状况，为今后开展精神卫生工作提供科学依据。[方法]采用按比例分配分层抽样法，对886名学生进行精神卫生知识和SCL-90症状自评量表问卷调查。[结果]学生精神卫生知识知晓率56．4％（489／866）；心理卫生问题（阳性症状）检出率26．9％（227／844），心理问题均集中反映在强迫、人际关系敏感和抑郁等方面，其发生率分别h21．7％、13．3％和10．1％；[结论]大学生精神卫生现况形势严峻，需进一步加大精神卫生工作力度。     

老年人肺结核的健康教育

近年来，在世界范围内广泛地为小儿接种了卡介苗，使一些儿童和青少年基本获得免疫力，因而结核病开始侵袭中老年人。由于老年人免疫功能下降，抗病能力不强，从而易被结核菌侵犯。另外，以往有“年过半百，不得结核”的错误观念，致使老人本身及医生失去警惕，再加上老人结核病的症状错综复杂。常被大量误诊、漏诊，致使结核病在老年人中互相传染，因而健康教育显得尤为重要。健康教育是按体护理实践的重要部分。它是以医院为基地，以病人及其家属为对象，通过有目的、有计划的教育，使之了解和增进健康的知识，减轻心理负担，主动配合治疗和护理，减少并发症。此外，增加护理人员与病人及家属语言、情感的沟通与交流，一改过去那种“无言的操作。无言的护理”状况，把健康教育贯穿于病人从入院到出院的全过程，有助于康复治疗。     

福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.