增殖细胞核抗原在胃肠道平滑肌肿瘤中表达的临床意义

探讨增殖细胞核抗原表达与胃肠道平滑肌肿瘤的关系。方法 采用免疫组化Ｓ－Ｐ法检测８６例ＧＩＳＭＴ中ＰＣＮＡ的表达情况。结果 ＰＣＮＡ表达按正常胃肠道平滑肌组织，平滑肌瘤，平滑肌肉瘤Ⅰ，Ⅱ，Ⅲ级的依次明显递增，同时，ＰＣＮＡ的表达与肿瘤的性质，大小，中心有无坏死有明显关系。     

Sysm exF系列血细胞计数仪堵孔对策

新泰市人民医院检验科 1993年购进 Sysmex F80 0血细胞计数仪 ,相继购进了 F82 0血细胞计数仪 ,血常规的检测已基本实现半自动化。多年来使用该仪器认为它有快速、操作简便等很多优点。但在使用过程中经常出现堵孔现象 ,屏幕上显示clog,无法工作 ,我科处理堵孔对策积累了丰富经     

宁红欣对34例骨科关节置换手术病人疗效观察

系统观察宁红欣(rHLdEPo)对骨科择期手术髋，膝关节置换术。34例病人术前红细胞动员。术后红细胞恢复的临床疗效。方法将宁红欣分别于术前5天，术前1天，术后当天，术后3天，术后7天皮下注射促红细胞生成素，观察临床症状以及用药前后血红蛋白，红细胞压积，网织红细胞计数，血清铁，血清铁蛋白。结论宁红欣可有效减少异体血的输入，在避免病毒等传染性疾病方面具有很大意义。     

CALCIUM ANTAGONISTS IN PREVENTION OF HYPERTENSION AND STROKE IN STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS

To investigate the effect of Calcium antagonists (Ca-An) with different tissue specificity in the devel- opment of hypertension and stroke in salt-loading SHRSP, three experiments were conducted. In exper- iment I (1), 50 8-week-old male SHRSP were divided into three groups and given nifedipine (NF, 32mg / kg /day), menidipine (MN 32mg / kg / day)and placebo (control group)respectively. In the controJ group 83.3%(15 / 18)died of stroke and 17 showded renal vascular sclerosis. Their average lifespan was 84 days. NF and MN significantly re- duced systolic blood pressure (SBP), and no stroke of renal vascular sclerosis developed.ln experiment I(2), 54 7-week-old male SHRSP were divided into three groups (18 in each group). They were treated with nimodipine (NM)20mg / kg / day, 2mg / kg / day and placebo respectively. NM (20mg / kg / day) markedly lowered SBP and postponed the onset of stroke. Only 11% died in 17 weeks. NM (2mg / kg / day did not lower SBP but postpond the onset of stroke. In exper- iment 11 (1), 29 10-week-old female SHRSP were di- vided into three groups: Group A was given NF 32mg / kg / day, group B was parathyoidectomized (PTX) and group C served as control. PTX group did not lower SBP but could postpone the onset of stroke. In experiment Ⅱ (2), 33 male SHRSP were divided into three groups and ticated as desctibed above :in experiment Ⅱ (I)(ll in each group). Seven weeks after the experiment, the brain blood flow of NF group was significantly greater (67.5%)than that of the control and PTX groups. In experiment II, 27 7-week-old male SHRSP were divided into three groups as described above in experiment I(2). Two weeks after the treatment, significant difference was found in norepinephrine (NE)contents of the anterior hypothalamic region (AHR)between NM (20mg / kg / day)group and control group (2 870 vs 2 304 pg / mg tissue). Our results show that Ca-An (nimodipine)can re- verse the NE depletion by high salt in SHRSP, thus lower SBP and prevent stroke.     

囊袋内人工晶体植入的技术改进：——介绍一种自制人工晶体植入器

囊袋内固定使人工晶体处于最佳的生理位置,避免了晶体攀与色素膜组织的接触,减少了眼组织的损伤,术后并发症少,视力恢复好。但是囊袋内固定技术上要求高,手术操作难度加大,尤其上攀囊袋内植入。我们制做了一种后房型人工晶体囊袋内植入器,并在操作技术上加以改进,使囊袋内植入变得简单、快捷、安全、可靠。介绍如下。一、植入器的制做: 用9号腰脊穿刺针,将针头的前段去掉一截,断端打磨平整光滑,使针芯较针头长出1mm左右。针头保留的长度可根据个人的习惯,一般以40～60mm为宜(图1)。     

超氧化物歧化酶对重症急性胰腺炎干预的实验研究

目的　探讨超氧化物歧化酶 (superoxidedismutase ,SOD)对急性胰腺炎的作用机制及治疗效应。 方法　5 4只雌性大鼠随机分为假手术组、重症急性胰腺炎模型组 (SAP)、SOD治疗组 (SOD +SAP)。经胆胰管内加压注射 5 %牛磺胆酸钠 0 .1ml/10 0 g建立SAP模型。SOD治疗组在建立SAP模型前 30min按 2 0 0 0 0U/kg体重给大鼠后肢肌注给药。在建模后 3h、6h、12h 3个时间点分批 (每组每批 6只 )将大鼠处死 ,经心脏取血检测血清淀粉酶、超氧化物歧化酶、丙二醛水平。结果　SOD治疗组在各个时间点的血清淀粉酶水平较SAP组均明显下降 (3h时 ,P <0 .0 1,6h、12h时 ,P <0 .0 5 )。SOD治疗组 3h、6h点血清SOD水平明显高于SAP组 (P <0 .0 1) ,12h点则无显著性差异 (P >0 .0 5 )。SOD治疗组血清MDA水平在 3h、6h点明显低于SAP组 (P <0 .0 1) ,12h点则与SAP组相近 (P >0 .0 5 )。SOD治疗组的胰腺组织病理评分在 3h点明显低于SAP组 (P <0 .0 5 ) ,6h、12h点则趋于一致 (P >0 .0 5 )。结论　超氧化物歧化酶能减轻SAP胰腺组织损害和降低血清淀粉酶水平 ,对重症急性胰腺炎具有一定的治疗作用。     

维持性腹膜透析患者生活质量的研究

目的了解维持性腹膜透析患者的生活质量及其影响因素，为提高患者生活质量提供依据。方法对31例维持性腹膜透析患者，应用生命质量量表(MOS SF-36)、自评抑郁量表(SDS)、家庭功能问卷(Family APGAR)进行测评调查。结果本组维持性腹膜透析患者生活质量的8个维度分。均显著低于一般人群，差异有显著性；生活质量影响因素主要有年龄、性别、透析年限(月)、费用来源、抑郁等。结论根据患者实际情况，采取个体化干预措施，加强患者及家属对抑郁的认知和健康宣教，提高患者生活质量。     

济南市332例性罪错妇女性传播感染检测结果分析

性罪错妇女是性传播疾病（STD）、AIDS的高危人群，其性病病原体检出率常高于一般人群。为了解近年来济南市性罪错妇女性病感染情况，我们于2004年9月～2005年11月对济南市公安局收容教育所卖淫妇女泌尿生殖道分泌物、血液进行检测，结果如下。     

16例马尾神经损伤诊治的回顾性分析

１６例马尾神经损伤诊治的回顾性分析赵毅＊方睿才＊扬华马尾神经位于脊髓末端，腰椎管平面。因其在椎管内相应空间较大，而且有硬膜，脑脊液保护，除非严重创伤，其直接受损伤机会较少，临床马尾神经损伤常见于腰椎间盘脱出症，马尾肿瘤，脊柱结核和硬膜外穿刺等原因。...     

对参芪补剂升血色素和抗疲劳作用的研究

用参芪补剂对小白鼠连续灌胃１５日，实验结果表明，此补剂可明显延长其游泳持续时间，具有较强的抗疲劳作用。在此基础上，又让自行车运动员连续服用补济６周，观察到参芪补剂能升高血色素；降低运动后尿蛋白，心率和舒张压。参芪补剂中各成份的综合功效能提高运动能力和比赛成绩。对服用者赛前药检结果呈阴性，表明补剂不含兴奋剂成份，服用安全可靠。