HPLC法测定枸杞子中甜菜碱的含量

目的建立枸杞子中甜菜碱含量的HPLC测定方法。方法采用磺酸基团键合硅胶的阳离子交换剂(SCX)为填充剂;流动相为乙腈-0.05 mol.L-1磷酸二氢钾-磷酸(15∶85∶0.18);检测波长为192 nm。结果甜菜碱浓度线性范围为0.40~2.40μg;甜菜碱的平均回收率为98.99%,RSD为0.86%(n=6)。结论该法灵敏度高,结果准确,可作为枸杞子中甜菜碱的定量测定方法。     

累及肠道坏疽性脓皮病一例

坏疽性脓皮病(PG)是一种罕见的慢性复发性溃疡性皮肤病,病因和发病机制不明,其组织病理学改变属于嗜中性皮肤病.多数PG患者伴有全身性疾病,其中最常见的是IBD、关节炎和血液系统疾病.部分患者可有非常罕见的皮肤外PG表现,累及肺、肠道、角膜、肝脏、脾脏、心脏、骨、肌肉和中枢神经系统等.现报告北京医院消化内科收治的1例由包...     

经皮冠状动脉介入术后双联抗血小板治疗 致消化道出血一例

本文报道了1例老年男性患者,因消化道出血就诊,既往曾行经皮冠状动脉支架介入手术,术后双联抗血小板治疗,胶囊内镜检查提示小肠多发隔膜样狭窄伴溃疡糜烂,符合非甾体类抗炎药引起小肠黏膜损伤表现。但追问病史,患者服用双联抗血小板药物治疗前曾有过小肠不全梗阻病史,因此小肠黏膜的病变是先天存在还是药物相关尚值得思考。     

腹部手术患者疼痛信念的调查研究

目的 了解腹部手术患者的疼痛信念,为有效解除患者疼痛提供理论依据.方法 采用疼痛和麻醉性镇痛药信念量表对136例腹部手术患者进行疼痛信念调查.结果 腹部手术患者疼痛信念总分为29.26±2.20,麻醉性镇痛药不良反应评分为14.43±1.25,忍耐疼痛评分为14.86±1.16;不同文化程度患者的疼痛信念评分比较,差异有显著性意义(P<0.05).结论 腹部手术患者整体疼痛信念趋负向,需对患者加强疼痛控制知识教育.     

幽门螺旋杆菌根除治疗对老年人Barrett食管复发的影响

Objective To investigate the relationship between the recurrence of Barrett esophagus (BE) and Helicobacter pylori (Hp) eradication therapy, according to endoscopic follow-up outcomes in the elderly patients with BE after endoscopic argon plasma coagulation (APC). Methods A total of 201 elderly patients were enrolled to be treated with APC, including 53 patients without Hp infection (control group) and 148 cases with Hp infection (infection group), then the infection group was randomly divided into two groups: infection group A (n=74) and infection group B (n=74). After APC, all patients were given acid suppression therapy with omeprazole infusion 40 mg twice daily for 7 days, then omeprazole capsules 20 mg twice a day orally, the overall time was 2months. The patients in infection group B received Hp eradication therapy with two of the following three kinds of antibiotics for 2 weeks: amoxicillin 500 mg twice a day, clarithromycin 500 mg twice a day and tinidazole 500 mg twice a day. All patients received reexamination of endoscopy and pathology, and underwent 24-hour esophageal pH test 1, 3, 6, 12 and 24 months after treatment.Results By APC treatment for an average of 2.4 times (1-3 times), 1 month after treatment, all BE epithelium disappeared and stratified squamous epithelium was repaired completely. Reflux esophagitis (RE) and BE in some cases were found in 3 groups 3 months after therapy. The relapse incidence of RE was significantly increased at 6 months after therapy [control group: 22.6%, infection group A:12.2o%and infection group B: 17. 6%, t = 2.21, 2.17 and 2.30,P＜0. 05]. At 12 months after therapy, the relapse incidence of BE was significantly increased [control group: 22.6%, infection group A: 18.9% and infection group B: 23.0%, t=2.11, 2.19 and 2.32, P＜0. 05]. All patients presented pathological gastro-esophageal reflux (DeMeester index＞14.72) before treatment. At 1 month after therapy, all patients returned to normal DeMeester index[control group: 14.5, infection group A: 15.2 and infection group B: 12.0, t=2.09, 2.22 and 2.15, P＜0. 05]. At 6 months after treatment, DeMeester index increased (t=2.29, 2.33 and 2.14, P＜0.05). But there were no significant differences among 3 groups (P＞0. 05). Conclusions The elderly BE patients with HP infection in gastric antrum can receive APC treatment plus Hp eradication treatment, but it has no significant effect on long-term prognosis for BE patients. APC treatment can completely remove BE epithelium, long-term acid suppression therapy may delay recurrence of BE.     

1916名护士心理咨询需求状况及相关因素研究

护士是一个特殊的职业群体,其工作对象是身心状况都处于相对低水平的患者,同时护理工作要面对危重患者多、自身工作危险性大等应激因素,是医疗卫生行业中压力最大的职业之一[1],其心理健康状况直接影响他们的学习、生活,甚至关系到护理工作质量和护理队伍的稳定[2].     

手部烧伤病人综合健康状况及护理干预研究进展

手是人体的重要器官之一,因其显露在外,容易烧伤,伤后对治疗要求极高,既要最大限度地恢复手功能,同时要取得满意的外观,减轻病人的身体及心理障碍[1]。烧伤病人手部功能的恢复引起广泛的关注,究其原因:一方面,烧伤人数多。钟德才     

4R危机管理理论在护理风险管理中的应用

目的:探讨4R危机管理理论在护理风险管理中的应用。方法:从缩减、预备、反应、恢复4个阶段对护理风险管理问题进行分析,提出各阶段护理风险的应对策略,提高护理风险管理能力。结果:4R危机管理理论为护理风险管理提供了新的视角,对护理安全管理具有重要的指导意义。     

本科实用型护理人才临床能力期望的调查研究

目的 调查不同群体对本科实用型护理人才临床能力的期望状况.方法 采用本科实用型护理人才临床能力期望问卷,对护理管理者、临床带教教师、本科学历护士、本科实习学生、护理院系专职教师、临床医生进行问卷调查,分析本科实用型护理人才应具备的临床能力,并比较不同群体的差异.结果 临床处置能力和沟通能力排在前两位,科研能力排在最后一位.不同群体对临床能力的重要性评价存在一定差异,护理管理者对管理能力和职业素养的评分较高,学生对观察病情、发现护理问题、制订护理方案等的评分低于带教教师.结论 临床处置能力和沟通能力是本科实用型护理人才被期望具备的首要能力,应引起护理管理者和护理教育者的重视.     

表格式专科护理记录单在优质护理示范病区中的应用效果,

目的 设计泌尿外科表格式专科护理记录单并探讨其应用效果.方法 根据泌尿外科专科特色设计表格武护理记录单,对98例住院患者同期使用新旧两种护理记录单进行书写记录,比较两种护理记录单所用的时间、纸张页数及质量评分差异.结果98例住院患者表格武专科护理记录所用时间、纸张页数比原护理记录明显减少,质量评分明显提高.结论表格武专科护理记录单可大大减少护理记录时间及记录纸张页数,提高护理记录质量,且更能体现专科护理观察重点,利于了解患者的病情及诊疗护理进展,书写界面简洁明了,值得推广.