太溪和丘墟穴捻针时不同脑功能区的激活

A number of previous studies of acupuncture acupoint specificity have used sham acupoints,sham acupuncture or meridian acupoints at a great distance from each other as controls in functional MRI (fMRI) experiments.However,few studies have compared different meridian acupoints within the same segment,which are associated with similarly intense needle sensations.We performed fMRI on 12 healthy young volunteers and observed differences in brain activation elicited by acupuncture of the Taixi (KI 3) and Qiuxu (GB 40) acupoints.Acupuncture was applied at the Taixi and Qiuxu acupoints,using a multiple-block fMRI design with three blocks,involving three alternations of resting and task phases.After scanning,needle sensation was assessed.The behavioral results revealed that the subjective needle sensation was similar between the Taixi and Qiuxu acupoints.The fMRI results revealed that acupuncture at the right Taixi acupoint activated the right superior temporal gyrus (BA 22),left middle frontal gyrus (BA 46) and inferior frontal gyrus (BA 45),bilateral parietal lobe postcentral gyrus (BA 2),right parietal lobe (BA 3),and left parietal lobe (BA 40).Acupuncture at the right Qiuxu acupoint activated the left superior temporal gyrus (BA 42),right parietal lobe postcentral gyrus (BA 40,BA 43),right inferior frontal gyrus (BA 47),bilateral superior temporal gyrus (BA 22),and right insula BA13.These results suggest that the right Taixi and Qiuxu acupoints activated different brain areas.     

电针大脑中动脉梗死大鼠人中穴(DU26)改善运动功能的最佳刺激参数

The selection of electro-acupuncture parameters remains poorly unified between clinical studies.The present study observed the effects of electro-acupuncturing Renzhong (DU 26) with different stimulation parameters on motor function recovery following middle artery occlusion injury in rats.Results showed an optimal stimulation parameter for Renzhong electro-acupuncture that was low frequency and mild current (2 Hz,1 mA) significantly improved cortical excitability and conductive function,and promoted recovery in a rat model of motor function in middle artery occlusion.Frequency had a greater impact than current or interaction,and played a critical role in electro-acupuncture therapy.     

中频率短时间针刺不同穴位对脑缺血模型大鼠脑血流量的影响

目的：探讨穴位的特异性效应及针刺频率对其特异性的影响作用。方法：Wistar成年雄性大鼠132只,随机分为正常组、模型空白组和针刺组,针刺组又随机分为非穴组和“醒脑开窍”针刺法各主穴组,即水沟组、内关组、尺泽组、三阴交组和委中组。复制大鼠大脑中动脉缺血模型（MCAO）,分别对以上穴区以及非穴区,施以频率2次／s、持续时间5s的针刺干预,观察脑血流量的变化。结果：当针刺频率为2次／s、持续时间5s时,针刺组（包括非穴组与“醒脑开窍”针刺法各主穴）与模型空白组比较,脑血流均有不同程度提高,内关组、委中组与模型空白组、非穴组比较具有统计学意义（P〈0．05）。结论：穴位具有特异性,其特异性受针刺参数影响;醒脑开窍针刺法能取得较好的临床疗效,是不同穴位及其最佳针刺参数共同作用的结果。     

针灸临床适应病证与未来展望

针灸是在中国特定的自然与社会环境中生长起来的科学文化知识,蕴含着中华民族特有的精神、思维和文化精华,涵纳着大量的实践观察、知识体系和技术技艺,凝聚着中华民族强大的生命力与创造力,是中华民族智慧的结晶,也是全人类文明的瑰宝.2006年5月20日,针灸经国务院批准列入第一批国家级非物质文化遗产名录.2010年联合国教科文组织保护非物质文化遗产政府委员会第五次会议审议通过中国申报项目“中医针灸”,将其列入“人类非物质文化遗产代表作名录”,这是对中国传统医学文化的认可.     

针刺对实验性脑梗塞大鼠基因转录影响的研究

本研究以热凝法阻断大鼠一侧大脑中动脉造成实验性脑梗塞模型,观察了实验性脑梗塞模型大鼠脑缺血后不同时段皮质、纹状体、海马早期快反应基因c -fos、HSP70基因表达水平及针刺的干预作用,从基因水平探讨了针刺治疗脑梗塞的作用机制。