不能切除的肝癌术中治疗模式的探讨

自１９６４年４月－１９９３年７月对２００例不能切除的肝癌术中多种模式治疗。患者均经手术及病理证实。按治疗方法分为两组。１组：１１５例单纯作肝动脉插管化疗（ＨＡＩ），其１、２年生存率分别为１０．４％和１．７％，仅１例生存６５个月；Ⅱ组：８６例术中作肝动脉栓塞化疗（ＨＡＣＥ）和加用肝动脉结扎（ＨＡＬ）或伴有波刀肿瘤固化（ＭＩＣ）、或伴有纯酒精肿瘤内注射（ＥＩＴ）的多模式治疗，其中１、２、３和５年生存率     

烧伤病人休克期血浆ANP、BNP含量变化

目的 观察烧伤病人休克期血浆中ANP（心钠素）、BNP（脑钠素）含量变化，探讨其临床意义。方法 选取伤后8h内入院的烧伤休克期住院病人14例，抽取病人静脉血3mL，用放射免疫方法，检测ANP、BNP含量，并与正常成人作对照。结果 烧伤患者休克期血浆中ANP、BNP含量明显高于正常成人，差异有显著性（P〈0．01）；随烧伤面积增大ANP、BNP含量增大，BNP比ANP变化更为明显（P〈0．01）。结论 烧伤后血浆中ANP、BNP含量明显上升；BNP含量的变化比ANP更敏感；休克期ANP、BNP含量的变化可能与容量失衡有关。     

血管性痴呆与五脏气机关系的探讨

本文从血管性痴呆的病位着手 ,结合五脏气机的生理病理变化 ,探讨了五脏气机失常与血管性痴呆的密切关系     

针刺治疗中风机理研究进展

从血液流变学、血流动力学、电生理学、生化指标、神经递质和神经元、分子生物学等方面综述了近年来针刺治疗中风的机理研究，提出需进一步深入探讨的方向。     

两性之爱怎样才幸福

对于这个问题一般来说有三种观点，第一种是艺术家式——真正的爱情无不是充满艰辛和曲折的，没有爱的折磨就不会有爱的幸福，比如说《简·爱》，再比如说《罗丹的情人》。     

软组织肉瘤的复发和治疗(综述)

 由中胚层发生的软组织肉瘤，以纤维肉瘤，脂肪肉瘤，横纹肌肉瘤、平滑肌肉瘤，滑膜肉瘤、神经纤维肉瘤等较常见，有些不能分类的未分化肉瘤常以细胞形态命名，如梭形细胞肉瘤、圆形细胞肉瘤等，有些软组织肉瘤组织来源不明的如巢状软组织肉瘤等。软组织肉瘤临床上比癌少见，约占全部恶性肿瘤死亡的0. 5~1. 2%^。但是，在诊断和治皆方面仍存在不少问题，其中最重要的是治疗后的局部复发，为治疗失败最常见的原因。近年来，对减少其局部复发和治疗方法上取得一些进展，现综述如下，供临床参考。     

吸入性损伤治疗十年回顾

目的：分析各种不同的治疗方法对烧伤吸入性损伤的疗效。方法：回顾性地调查近十年收治的所有吸入性损伤病人,比较前三年、中三年及后四年的救治情况及效果。结果：前三年较近四年死亡率明显为高;气管切开时间逐步提前,呼吸机使用率明显增多,呼吸机使用时间逐渐缩短,早期切削痂手术增多。量子化血使用较前明显增多,中期三年较近四年死亡率无显著差异,但三度烧伤面积近四年明显高于中三年。结论：重度吸入性损伤病人早期气管切开、创面的早期切削痂处理、创面覆盖物的使用、呼吸机的早期使用及及时的停机,量子血的使用等均对愈后有明显的影响。     

药物经济学在医院药事管理工作中的应用

目的 探讨药物经济学在当前医院药事管理工作中的作用.方法 依据药物经济学的基本理论及研究方法.结果 药物经济学可为医院药事管理工作提供客观的决策依据.结论 药物经济学在医院药事管理工作中,有很多值得探究和运用的地方,有待于进一步研究和应用.     

强化精氨酸肠内营养对烧伤患者营养状况和细胞免疫的影响

Objective To investigate the effects of arginine enriched enteral nutrition (EN) on nu-tritional status and cellular immunity of severely burned patients. Methods Randomized, single blind, parallel and positive control investigation was employed in the study. Thirty severely burned patients were di-vided into enteral immune nutrition (EIN) group and EN group. Sixteen patients in EIN group received en-teral nutrition enriched with arginine, while the other 14 patients in EN group received standard enteral nu-trition. Nutritional support was continued for 14 days. Gastrointestinal reaction of patients in 2 groups was observed. Fasting venous blood was drawn from patients of both groups before receiving nutrition treatment and on the morning of 7th, 14th day of treatment. Level of serum protein, hepatic function parameters, renal function parameters, fasting-blood glucose, and subpopulations of T lymphocytes in peripheral blood were determined. Results (1) Incidence of gastrointestinal side effect in EIN group (25.0%) was close to that of EN group (21.4% , P>0.05). (2) Compared with pre-treatment days, levels of prealbumin and transferrin in serum of patients in 2 groups on 7th and 14th post-treatment days were significantly increased (P<0.05 or P<0.01), but there was no significant difference between 2 groups. The level of total serum protein on 14th day of treatment of patients was significantly increased in both groups, and that of EIN group (66±7 g/L)was significantly higher compared with that in EN group (64 ± 11 g/L, P<0.05). The level of serum albumin (29±5, 32±5 g/L, respectively) of patients in EIN group on 7th and 14th day of treat-ment were significantly higher than that (26±4 g/L, P <0.05) in pre-treatment days, however there was no significant difference in EN group. (3) There was no significant difference in respect of hepatic function, renal function, and fasting-blood glucose between pre-treatment and post-treatment periods in both groups (P>0.05). (4) The ratio of CD4+ , CD8+ on 14th day of treatment in EIN group was close to that of pre-treatment level. In EN group, cell percentage of CD4+ significantly decreased, while that of CD8+ significantly increased (P<0.05), and CD4+ was significantly higher [(56±8) %] in EIN group than that in EN group [(55±12) % , P <0.05]. In both groups, cell percentage of CD3+ was significantly higher than that in pre-treatment days (P<0.05), while there was no obvious change in CD4+/CD8+. Conclusions Arginine enriched enteral nutrition can effectively improve nutritional status and cellular immune function of burn patients.     

烧伤创面的皮肤移植近况

采用切痂植皮术,尽早消灭创面是抢救大面积深度烧伤病人的重要措施,但此类患者自体皮源常严重不足。为了解决烧伤治疗中皮源供应问题,自1881年Girdner报道应用尸体皮移植以来,许多学者对异体,异种