生精胶囊治疗少精子不育症的临床研究

目的：探讨生精胶囊治疗男子少精子不育症的临床疗效。方法：将84例少精子不育症患者以就诊顺序随机分为治疗组（生精胶囊组）46例和对照组（五子衍宗片组）38例,疗程均为90天,然后进行疗效判定,比较两组总有效率。结果：两组总有效率分别为84．78％和60．53％,差异有统计学意义（P〈0．05）,治疗组疗效优于对照组。结论：生精胶囊对男子少精子不育症有较好的疗效。     

土金炎清汤治疗慢性前列腺炎43例临床观察

目的观察土金炎清汤对慢性前列腺炎的疗效。方法将80例慢性前列腺炎患者以就诊顺序,按随机数字表法随机分为治疗组和对照组,治疗组予以土金炎清汤,对照组予以前列平胶囊,两组均以30d为一疗程,比较治疗后两组总有效率。结果两组治疗后,总有效率差异有统计学意义（P〈0．01）,治疗组疗效优于对照组。结论土金炎清汤对慢性前列腺炎有较好的疗效。     

一组新型ADP诱导的正常血小板聚集图象参数

本文应用血小板聚集数学模型和计算机模拟技术,测量出一组能反应正常血小板聚集全过程的图像参数即P_0、P_1、P_2、K_1、K_2、K_3和T_0。分析该组参数的分布特征和相互关系,结果表明,反映聚集速率和时间的参数(K_1、K_2、T_0)是引起图象改变的敏感指标;图象初聚与次聚呈极显著正相关(P<0.01或0.001);通过因子分析提取出三个共性因子即:散聚决定因子、聚集幅度因子和聚集速率因子。7个参数反映散聚过程和聚集幅度能力较强而反映聚集速度的能力稍差。     

Expression of Platelet Membrane Glycoprotein Ib/Ⅸ/Ⅴ Complex,a Receptor of Thrombin,in Patients with Hemorrhagic Thrombopathy

To investigate the role of platelet membrane glycoprotein (GP) Ib/Ⅸ/Ⅴ complex and its subunit GP Ibα in patients with hemorrhagic thrombopathy (HT), the expressions of GP Ib/Ⅸ/Ⅴ complex and GP Ibα,defined as mean fluorescence intensity (MFI), were assessed by flow cytometry. The maximum aggregation of platelet was determined by turbidity method. These indicators were compared among 68 HT patients with the presenting complaint of hemorrhage, 33 well-controlled HT patients and 32 normal healthy subjects. The results showed that the MFI of GP Ib/Ⅸ /Ⅴ complex and GP Ibα was markedly lower in HT patients with current hemorrhage than that in the healthy subjects, with difference being statistically significant (P<0.05). There was no significant difference in the expressions of GP Ib/ Ⅸ/ Ⅴ complex and GP Ibα between well-controlled HT patients and normal healthy subjects (P>0.05). It was concluded that the expression of GP Ib/Ⅸ /Ⅴ complex, the receptor of thrombin and von Willebrand factor, was down-regulated in HT patients with current hemorrhage, which might result in the dysfunction of platelet aggregation and recurrence of HT.     

红升丹外用治疗尖锐湿疣30例临床观察

目的:观察红升丹治疗尖锐湿疣的临床及实验室检测结果。方法:对疣体消毒后以红升丹点涂于创面,并对其血汞及尿汞含量、肝肾功能进行严格的监测。结果:本组30例中,所有患者在1~3周中疣体均已脱落,创面愈合。治疗结束后6个月的随访中无复发病例,血汞及尿汞含量、肝肾功能均在正常值范围内。结论:红升丹治疗尖锐湿疣有较好的疗效。     

土金炎清汤治疗Ⅲ型前列腺炎42例临床观察

目的：观察土金炎清汤治疗Ⅲ型湿热挟瘀型前列腺炎的临床疗效。方法：将84例Ⅲ型前列腺炎（湿热挟瘀证）患者随机分为治疗组（土金炎清汤组）42例和对照组（前列平胶囊组）42例,两组均以30d为1个疗程,比较治疗1个疗程后两组患者总有效率及中医证候学评分。结果：两组总有效率分别为88.10%和66.67%,差异有统计学意义（P〈0.01）;中医证候学评分显著下降,与对照组比较,差异有统计学意义（P〈0.01）。结论：土金炎清汤对Ⅲ型前列腺炎（湿热挟瘀证）有较好的治疗作用。     

Fas/FasL基因和蛋白表达对精子浓度和活力的影响

目的:探讨精液中细胞凋亡Fas/FasL基因和蛋白的表达对精子浓度和活力的影响.方法:将精液标本根据精子浓度和前向运动精子百分率分为4组:正常精子组、弱精子症组、少精子症组和少弱精子症组,每组20例.分别检测各组精液常规参数、Fas/FasL蛋白浓度、Fas/FasL基因表达水平.结果:①4组精子的浓度(×106/ml...