综合针刺法在胸外科手术后镇痛效果观察

本组30例胸外科术后采用综合针刺珐镇痛、先后应用温针、腕针、耳针、水针。以杜冷丁25毫克肌注作自身对照。用钾离子测痛和血液循环功能监护仪来考核镇痛效果和调整功能。实验结果：1、痛阈提高以腕针最为明显，耐痛阈提高出现递进、叠加镇痛效果。2．各种针刺法均比杜冷丁镇痛效果显，P<0．01。3．针后脉率减慢，心肌收缩力加强、搏出量增加。     

放射线联合p53基因及内皮抑素治疗小鼠前列腺癌皮下移植瘤

Objective To test the hypothesis that p53 gene therapy combined with endostatin can enhance tumor response to radiation therapy of RM-1 mouse xenograft prostate cancer and to investigate its mechanism. Methods A mouse prostate cancer model was established. Then mice with xenograft tumor were randomly divided into group A (control), B (radiation), C (radiation and rAdp53), D (radiation and rh-endostatin) and E (radiation and rAdp53 and rh-endostatin). On day 1, rAdp53 was injected intra-tumorously with 1 × 1010 vp per animal to group C and E. From day 1 to 14, rh-endostatin was given 15 mg/kg intraperitoneally daily to group D and E. On day 4 single fraction of 15 Gy was given to tumors in groups B, C, D and E. Normal saline was injected intra-tumorously or intraperitoneaUy accordingly as control. No treatment was done to group A. Tumor volume was measured daily. Samples were collected on Days 5, 10 and 15. Ki67, CD31, p53 and VEGF were detected by means of immunohistochemistry. Results (1) Radiation alone, radiation combined with intra-tumorous injection of Adp53 and/or intraperitoneal injection of rh-endostatin resulted in tumor growth arrest of RM-1 cells in vivo (P = 0.000). Radiation combined with both rAdp53 and rh-endostatin was the most effective treatment (P < 0.05). (2) All the four treatment groups had a decreased expression of mutant type P53 (P = 0.000). The expression of Ki67 in groups B and C were equal (P 0.05) and increasing (P = 0.000), respectively. Group D had a up-down-up curve (P < 0.05), but group E had a up-down one. On day 5 the expresion of VEGF in group E was the lowest (P < 0.05). An increased expression of MVD compared with the control was shown, and MVD in groups C, D and E were always higher than that in the control (P < 0.05). Conclusions The limitation of radiotherapy could be overcome by combination with beth p53 gene therapy and endostatin on the growth of mouse prostate cancer cell. Radiation, rAdp53 and endostatin have their own role but they can be interacted with each other.     

自理理论在护理产前子痫患者中的应用

在产前子痫患者护理中,我们应用了自理理论并取得了良好的效果,现将我科对2000年2月～2002年8月收治的36例产前子痫患者的护理,介绍如下。 1 入院时护理 产前子痫患者大部分昏迷、自理能力丧失,应用全补偿系统来满足病人自理需要。全补偿系统是指个体活动受限,全部需求由护士予以满足。首先     

冷冻、微波及微波联合干扰素治疗尖锐湿疣疗效观察

目的：观察冷冻、微波及微波联合干扰素治疗尖锐湿疣的临床效果。方法：将204例尖锐湿疣患者随机分为三组，分别给予冷冻、微波及微波联合干扰素治疗，观察治疗后临床疗效及其复发串。结果：微波联合干扰家组的复发率为10．0％，明显低于冷冻组33．3％和微波组20．6％(P＜0．05)。结论：微波联合干扰素治疗尖锐湿疣能提高治愈率，减少复发率。     

外伤性白内障术后二期人工晶状体植入术

目的 探讨外伤性白内障术后二期植入后房型人工晶状体的时机和手术方式。方法 对34例(34只眼)外伤性白内障术后无晶状体眼根据不同情况采用直接睫状沟植入法或缝线固定法进行二期植入后房型人工晶状体，观察两组患者的术后反应和治疗效果。结果 直接睫状沟植入法14只眼(41．2％)，缝线固定法20只眼(58．8％)，31只眼(91．2％)视力达到0．1以上，21只眼(61．76％)视力达0．3以上，28只眼(82．4％)术后矫正视力等于或高于术前最佳矫正视力。结论 选取合适的时机和方式二期植入人工晶状体，有助于减少术后并发症，提高视功能的恢复。     

儿童白血病的心理护理

儿童白血病的心理护理附院儿科（０４６０００）解卫红刘丽附院急症科张敏白血病是儿童最常见的恶性肿瘤，严重影响患儿的身心健康，白血病患儿的心理状况及是否配合治疗是康复的重要环节。近年来我科对６６例患白血病儿童重视了心理护理，取得较好效果，现报道如下：１临...     

维生素E、C和B_2联用对小鼠血糠的影响

本实验研究用四氧嘧啶造成小鼠糖尿病模型，灌胃给予小鼠按一定比例配伍的维生素Ｅ、Ｃ、Ｂ_２，观察其对小鼠血糖水平的影响。结果显示，维生素Ｅ、Ｃ和Ｂ_２联用能有效地降低小鼠的高血糖，其血糖值（３５．５１±６．０２ｍｍｏｌ／Ｌ）明显低于四氧嘧啶组（５２．５８±８．０３ｍｍｏｌ／Ｌ），两者之间差异有显著性意义（Ｐ＜０．０１）。     

骨髓增生异常综合征亚型分型标准的探讨

骨髓增生异常综合征(MDS)的亚型分型标准,国外多采用FAB标准。而国内有两种意见,一种主张按FAB标准,另一种主张采用FAB改良标准。其主要分歧在于亚型分型中是以原始粒细胞Ⅰ型+Ⅱ型,还是以原始+早幼粒细胞来判定。这一分岐在几次全国会议上均未得统一认识。亚型的确定直接影响治疗方针,现就我院1989～1991年收治的31例MDS讨论如下。