甘氨双唑钠联合放射治疗中晚期鼻咽癌临床研究

目的:观察甘氨双唑钠(sodiumglyci-didazole,CMNa)在中晚期鼻咽癌放射治疗中的作用。方法:60例中晚期鼻咽癌患者随机分观察组(CMNa 放疗)和对照组(单纯放疗组)各30例。CMNa静脉滴入,每次0·75g,每周1、3和5用药,用药后1h内放疗。放疗采用常规外照射方案。结果:鼻咽原发灶CR率在观察组和对照组分别是93%和73%,两组差异有统计学意义,χ2=4·320,P=0·0377。颈淋巴结CR率两组分别是90%和63%,两组差异亦有统计学意义,χ2=5·963,P=0·0146。两组毒副反应如皮肤、黏膜、消化道反应及血白细胞下降等差异无统计学意义,P>0·05。结论:CMNa联合放射治疗可提高鼻咽癌的肿瘤局部控制率,而毒副反应不增加。     

放疗联合紫杉醇化疗治疗中晚期鼻咽癌的疗效观察

目的观察放疗联合紫杉醇治疗中晚期鼻咽癌患者的疗效。方法分析放疗联合紫杉醇治疗58例中晚期鼻咽癌的局控率、生存率和毒副反应,并与57例单纯放疗相比较。结果综合组和单放组的治疗有效率为87.9%、71.9%,颈部淋巴结有效率91.5%、75.4%,差异均有统计学意义(P<0.05)。综合组的远处转移率低于单放组(P<0.05)。两组1~3年生存率均无统计学意义(P>0.05)。综合组主要不良反应为白细胞下降、胃肠道反应等,经治疗可改善。结论放疗联合紫杉醇可提高中晚期鼻咽癌的近期疗效,毒副反应可耐受,长期疗效有待于临床进一步观察。     

新医改方案：让公民能“看得懂”

按照国务院的工作部署，深化医药卫生体制改革部际协调工作小组在深入调研、集思广益的基础上，组织起草了《关于深化医药卫生体制改革的意见（征求意见稿）》，该意见稿现已全文公布，向社会征求意见。（新华网10月14日）     

选择性逆行胰胆管造影的体会

我院从1975年至83年共作选择性逆行胰胆管造影238例次(229例),获有诊断价值资料200例次(191例),占84.0％。77年以前共作9例,仅成功4例;78年到83年4月共作229例次(220例),成功220例次(211例),成功率为96.1％。     

外科创伤病人手术所致的焦虑状态调查

采用状态－特质焦虑问卷及10项躯体性焦虑测试题，对40例外科创伤病人手术前后的焦虑状态调查显示：术前状态焦虑量表评分显高于术后；术前躯体性焦虑评分显高于术后；高特质焦虑评分亚组与低特质焦虑评分亚组术前状态焦虑评分无显差异，但术后则前显高于后；急诊手术手术前后状态焦虑评分显高于择期手术；性别、年龄、平时性格特征及化程度对焦虑状态的产生无明显影响。     

针刺治疗急性病毒性黄疸型肝炎——附135例临床观察

我院传染科从1981年7月～1985年11月,采用针刺治疗急性病毒性黄疸型肝炎135例,取得了较好的疗效。现介绍如下: 临床资料病历来源本组病例系经门诊诊断为急性黄疸型肝炎收入住院的患者。性别、年龄 135例中,男性82例,女性53例     

国产卡马西平治疗多种神经精神疾病75例疗效观察

本文报道国产卡马西平治疗癫痫、三叉神经痛、偏头痛和躁狂症共75例,除偏头痛外均获满意疗效,痊愈与显著进步率分别为73、69、和69％。1/3患者治疗初期出现头晕、思睡、乏力、恶心、共济失调等副反应及白细胞轻度可逆性减少3例,治疗前、后肝功能与心电图检查对比均未见明显异常。     

ELECTRO-ACUPUNCTURE ANESTHESIA IN PITUITARY ADENOMA EXTIRPATION

It is clinically shown that the analgesic effect of electro-acupuncture anesthesia (EAA) for cranial operations is more effective than for other parts of the botly. Among all cranial operations the analgesic effect of prefrontal craniotomy is best. Since 1975, 43 patient.s with pituitary adenoma operated on under EAA had good or excellent results in 41/43. In this series the patients' general conditions and mental status were similar. The OPeration was carried out as a small osteoplastic flap craniotomy in the right frontal region. All acupuncture points used were close to the sensory nerve branches around the operative field. According to the puncture locations the cases are divided int0 2 groups. In Group A the points were very close to the nerves distributed in the frontal operative field includ- ing Zanzhu 攒竹, Yuyao 鱼腰, Ermen 耳门 and Shangguan 上关 In Group B point Chuan- liao 颧鼹 was located near the infraorbital nerve with another point at the ipsilateral ear lobe as a coupling point, both were a little farther away from the operative field. The good and excellent results in Group A and B included all patients except l in each group (statistically insignificant). Although a few patients com- plained or groaned slightly, they could tolerate the ent.ire operation. All points used in Groups A and B are close to sensory branches of trigeminal nerve and/or the analgesia is connected with changes of some neurochemical elements within the central ner- vous system (e.g. endorphine, 5HT). The authors' experience is that points close to sensory branches near the central nervous system have better EAA analgesic effect.     

恶性肿瘤患者血清Ⅳ型胶原的检测及意义

目的为探讨血清Ⅳ型胶原（ＣＩＶ）水平在恶性肿瘤诊断中的价值。方法采用竞争性放射免疫测定法检测１４１例恶性肿瘤患者血清ＣＩＶ水平,并分组分析不同恶性肿瘤患者血清ＣＩＶ水平的相关性。结果恶性肿瘤患者血清ＣＩＶ水平明显高于正常对照组（Ｐ＜０．００１）,各组恶性肿瘤患者血清ＣＩＶ水平无明显差别（Ｐ＞０．５）。结论检测血清ＣＩＶ水平对诊断恶性肿瘤有一定价值。