咳尔康口服液体外抑菌作用的研究

Objective To analyze the effect of Kecrkang oral Liquid on extracorporeal bacteriostasis. Methods Tube dilution method was adopted to test the effect of different concentrations of Keerkang oral liquid on bacillus coli, klebsiella pneumoniae, bacillus aeruginosus, staphylococcus aureus, staphylococcus epidermidis, β-Streptococcus hemolyticus, streptococcus pneumoniae, haemophilus influenzae and candida albicans. Results Keerkang Oral Liquid has obvious inhibited effects to all the bacteria that mentioned above. Conclusion Keerkang Oral Liquid has obvious extracorporeal bacteriostasis and resistance to fungi.     

咳尔康口服液体外抑菌作用的研究

Objective To analyze the effect of Kecrkang oral Liquid on extracorporeal bacteriostasis. Methods Tube dilution method was adopted to test the effect of different concentrations of Keerkang oral liquid on bacillus coli, klebsiella pneumoniae, bacillus aeruginosus, staphylococcus aureus, staphylococcus epidermidis, β-Streptococcus hemolyticus, streptococcus pneumoniae, haemophilus influenzae and candida albicans. Results Keerkang Oral Liquid has obvious inhibited effects to all the bacteria that mentioned above. Conclusion Keerkang Oral Liquid has obvious extracorporeal bacteriostasis and resistance to fungi.     

咳尔康口服液体外抗病毒作用的研究

Objective To analyze the inhibitive effect of Keerkang Oral Liquid on adenovirus (ADV3) , parainfluenza virus (HVJ) , respiratory syncytial virus (RSV) , and herpes simplex virus 1 (HSV-1) , herpes simplex virus 2 ( HSV-2 ) in cell culture. Methods Sensitive cell culture was adopted, and chick embryo kidney (CEK) cells and bit hamster kidney (BHK) cells were used to infect homologous virus. Keerkang Oral Liquid was given after 2 hours, then cytopathie phenomenon (CPE) was observed. Results When the amounts of infected virus are less than or equal to 100TCID50, the group which was given Keerkang Oral Liquid showed CPE, while the virus control group showed 25%～75% CPE. Besideds Keerkang Oral Liquid showed inhibitive effect on maximum non-venom concentration (TD0) , medium effective concentration (IC50), minimum valid concentration (MTC) and therapeutic index (TI) ofADV3, HVJ, RSV, BSV-1, and HSV-2 by 0.5, 0.25, 0A25-0.0625 ml/ml and 4.8 respectively. Conclusion Keerkang Oral Liquid has obvious inhibitive effects on ADV3, HVJ,RSV and HSV-1, HSV-2 in cell culture, which provides experimental basis for treating ADV3, HVJ, RSV and HSV-1, and HSV-2.     

金黄色葡萄球菌耐药性分析

目的：对医院分析金黄色葡萄球菌（SAU）耐药性现状给临床合理用药提供参考。方法：收集2005年-2007年临床分离的金黄色葡萄球菌培养鉴定,采用纸片扩散法测定12种抗菌药物的敏感情况进行分析。结果：220株金黄色葡萄球菌其中耐甲氧西林金黄色葡萄球菌（MRSA）为140株占63．6％。甲氧西林敏感金黄色葡萄球菌（MSSA）为80株占36．4％。金黄色葡萄球菌对12种抗菌药物的耐药率最高是青霉素G为85．5％。万古霉素耐药率为0。结论：甲氧西林敏感金黄色葡萄球菌对大多数的抗菌药物有较好的敏感性,耐甲氧西林金黄色葡萄球菌为多重耐药性。     

咳尔康口服液体外抑菌作用的研究

Objective To analyze the effect of Kecrkang oral Liquid on extracorporeal bacteriostasis. Methods Tube dilution method was adopted to test the effect of different concentrations of Keerkang oral liquid on bacillus coli, klebsiella pneumoniae, bacillus aeruginosus, staphylococcus aureus, staphylococcus epidermidis, β-Streptococcus hemolyticus, streptococcus pneumoniae, haemophilus influenzae and candida albicans. Results Keerkang Oral Liquid has obvious inhibited effects to all the bacteria that mentioned above. Conclusion Keerkang Oral Liquid has obvious extracorporeal bacteriostasis and resistance to fungi.     

咳尔康口服液体外抗病毒作用的研究

目的 探讨咳尔康口服液在细胞培养中对腺病毒3型(ADV3)、副流感病毒(HVJ),呼吸道合胞病毒(RSV)、单纯疱疹病毒1和2型(HSV-1,HSV-2)的抑制作用.方法 用敏感细胞培养法,采用鸡胚肾细胞(CEK)、Vero细胞,幼地鼠肾(BHK)细胞感染相应病毒2 h给药,观察细胞病变(CPE).结果 当病毒感染量≤100TCID50时,咳尔康口服液组无CPE,而病毒对照组有25%～75%的CPE.咳尔康口服液抑制ADV3、HVJ、RSV、HSV-1、HSV-2的最大无毒浓度(TDO)、半数有效浓度(IC50)、最小有效浓度(MTC)和治疗指数(TI)分别为0.5、0.25、0.125～0.0625 ml/ml和4、8.结论 咳尔康口服液在细菌培养中可显著抑制ADV3、HVJ、RSV和HSV-1,为治疗ADV3、HVJ、RSV和HSV-1感染提供了实验依据.     

咳尔康口服液体外抑菌作用的研究

目的 探讨咳尔康口服液的体外抑菌作用.方法 用试管稀释法,测定不同浓度咳尔康口服液对大肠杆菌、肺炎克雷伯荫、绿脓杆菌、金黄色葡萄球菌、表皮葡萄球菌、β-溶血性链球菌、肺炎链球菌、流感嗜血杆菌及白假丝酵母菌的作用.结果 咳尔康口服液有明显的抑菌作用.结论 咳尔康口服液在体外有明显的抑菌作用及抗真菌作用.     

咳尔康口服液体外抑菌作用的研究

Objective To analyze the effect of Kecrkang oral Liquid on extracorporeal bacteriostasis. Methods Tube dilution method was adopted to test the effect of different concentrations of Keerkang oral liquid on bacillus coli, klebsiella pneumoniae, bacillus aeruginosus, staphylococcus aureus, staphylococcus epidermidis, β-Streptococcus hemolyticus, streptococcus pneumoniae, haemophilus influenzae and candida albicans. Results Keerkang Oral Liquid has obvious inhibited effects to all the bacteria that mentioned above. Conclusion Keerkang Oral Liquid has obvious extracorporeal bacteriostasis and resistance to fungi.