THE EFFECT OF RADIX SALVIAE MILTIORRHIZAE COMPOSITA ON PEROXIDATION OF LOW DENSITY LIPOPROTEIN DUE TO COPPER DICHLORIDE

It is well known that plasma lipoprotein, particularly oxidized LDL, plays an important rolein the pathogenesis of atherosclerosis and atherosclerotic diseases. We used oxidized LDLgenerated by incubating LDL from healthy Persons with copper dichloride as a model to in-vestigate the antioxidate property of Radix Salviae Miltiorrhizae Composita (RSMC). Onphotos, the spot X1 and the spot X2 were clearly found in the control group after the dislysisinto copper dichloride for 24 and 48 hours, but they could not found in the RSMC group.The analysis of the constituents of lipids in LDL (by charring method) showed that afterdislysis the percentages of the spot X1 and the spot X2 in the RSMC group weresignificantly lower tban those in the control group (P< 0.01). The results suggest thatRSMC plays a potential role in antioxidation of lipuls or LDL.     

在深化改革中加强医院管理的体会

根据军队医院的根本职能和在市场经济条件下，加快医院建设与发展的客观需要。从三个方面总结了加强医院管理的体会。提出管理的核心是做人的工作；管理的基本思路是坚持从严管理、依法管理和综合治理；管理改革的关键是：要处理好履行根本职能和适应新形势加快医院建设的关系，使军队医院既能立足现有条件做好当前的保障工作，又能较快发展适应未来保障任务的需要。     

The Effects of Astragalus membranaceus and Tripterygium hypoglaucum on NK Activity in Systemic Lupus Erythematosus

ＴｈｅＥｆｆｅｃｔｓｏｆＡｓｔｒａｇａｌｕｓｍｅｍｂｒａｎａｃｅｕｓａｎｄＴｒｉｐｔｅｒｙｇｉｕｍｈｙｐｏｇｌａｕｃｕｍｏｎＮＫＡｃｔｉｖｉｔｙｉｎＳｙｓｔｅｍｉｃＬｕｐｕｓＥｒｙｔｈｅｍａｔｏｓｕｓＺｈａｏＸｉａｏ－ｚｈｏｎｇ（赵小忠）（Ｄｅｐａｒ...     

略论法国大革命中吉伦特派的人权思想

吉伦特派是十八世纪法国大革命中的一个重要派别,是大革命前期革命沿上升路线发展时三个相继执政的资产阶级党派中承上启下的一个。对吉伦特派的评价,法国史学界二百年来莫衷一是,而且似乎有不少偏颇之处,我国史学界三十余年来更显得偏激。作者认为,他们思想的核心是启蒙学者所阐明的人权学说,因而,本文拟对他们的人权思想略加阐述,并试用历史唯物主义的观点作一些剖析,希望能因此对他们作出一个比较客观的评价。     

Dual Exposure to Sevoflurane Improves Anesthetic Preconditioning in Intact Hearts

Background: Anesthetic preconditioning (APC) with sevoflurane reduces myocardial ischemia-reperfusion injury. The authors tested whether two brief exposures to sevoflurane would lead to a better preconditioning state than would a single longer exposure and whether dual exposure to a lower (L) concentration of sevoflurane would achieve an outcome similar to that associated with a single exposure to a higher (H) concentration.

Methods: Langendorff-prepared guinea pig hearts were exposed to 0.4 mm sevoflurane once for 15 min (H1-15; n = 8) or 0.4 mm (H2-5; n = 8) or 0.2 mm sevoflurane (L2-5; n = 8) twice for 5 min, with a 5-min washout period interspersed. Sevoflurane was then washed out for 20 min before 30 min of global no-flow ischemia and 120 min of reperfusion. Control hearts (n = 8) were not subjected to APC. Left ventricular pressure was measured isovolumetrically. Ventricular infarct size was determined by tetrazolium staining and cumulative planimetry. Values are expressed as mean +/- SD.

Results: The authors found a better functional return and a lesser percentage of infarction on reperfusion in H2-5 (28 +/- 9%) than in H1-15 (36 +/- 8%; P < 0.05), L2-5 (43 +/- 6%; P < 0.05), or control hearts (52 +/- 7%; P < 0.05).     

大学生美容行业就业状况调查实录

北京华侨大厦，首届美容院人才交流会顺利召开，295家美容美发企业现场求贤。据主办方介绍，举办此次大会的初衷是希望更多的大学毕业生和外行业专业人才加盟美容美发行业，提高美容业人才整体水平。而对于还未就业的应届毕业生来说，这也将是不错的就业机会。但出人意料的是，整场会议下来，参会人次才360多人。参会的企业抱怨没有招到合适自己的人才，这是一场有需求没供应的交流会。究竟美容美发人才供应在哪里出了问题呢？[编者按]     

Hepatoprotective effects of diethylcarbamazine in acute liver damage induced by carbon tetrachloride in rats

This research was carried out to determine a potential role of leukotrienes in the acute hepatotoxicity induced by CC14 in rats. An inhibitor of leukotrienes biosynthesis, diethylcarbamazine (DEC, 25 and 50 mg ·kg-1 ip) exerted hepatoprotective effects, decreasing the activity of alanine aminotransfer-ase in serum and the concentration of liver triglycerides. DEC reduced histological damage of liver evidenced by electron microscopy. The hepatoprotective effects of DEC were dose-dependent. The results favor the role of leukotrienes in CC14 hepatotoxicity.     

真核基因的转录调控

自从1953年Watson和Crick确立了DNA的双螺旋结构,近40年来分子生物学研究阐明了遗传信息的传递是由DNA→RNA→蛋白质的“中心法则”以及其逆向转录的补充。然而,直到70年代基因工程技术问世,才有可能深入研究基因表达的时空调控机制。真核基因中由组蛋白和DNA形成的“串珠状”核小体是染色质结构的基本单位。真核基因转录前染色质结构改变     

A群多糖脑膜炎菌苗最适免疫剂量的研究

近些年来对Ａ群多糖脑膜炎菌苗最适免疫剂量进行了一系列现场流行病学及血清学效果的对比研究。首先肯定了我国生产的菌苗与法国Ｍｅｒｉｅｕｘ研究所生产的苗苗在人体接种后观察一年内具有同等杀菌抗体反应。以后在严格对比下观察了国内生产的多糖菌苗接种３０μｇ及５０μｇ一年内的血清杀菌抗体反应。结果完全相同；而全身反应则３０μｇ为５０μｇ剂量的五分之一。在我国８０年代流脑流行地区内确证了３０μｇ免后人群保护率为９９％与国外５０μｇ的保护率（９７．２％）相似。国内连续三年在流行地区内对比观察了３０μｇ、与５０μｇ的流行病学预防效果，其人群保护率相似．与国外（Ｒｅｉｎｇｏｌｄ）．的报告亦相似。最后结论是本菌苗的最适免疫剂量为３０μｇ．不但其预防效果与５０μｇ相同，而且菌苗反应轻微，经济效益高，有利于在发展中国家推广使用。     

PHA RMA COKINETICS OF CUPRIC－BIS（SALICYLALDEHYDE－2－FURA NTHIOCA RBOXY－HYDRAZONATE） DICHLORIDE（CSFTCH） IN RABBITS

ＰＨＡＲＭＡＣＯＫＩＮＥＴＩＣＳＯＦＣＵＰＲＩＣ－ＢＩＳ（ＳＡＬＩＣＹＬＡＬＤＥＨＹＤＥ－２－ＦＵＲＡＮＴＨＩＯＣＡＲＢＯＸＹ－ＨＹＤＲＡＺＯＮＡＴＥ）ＤＩＣＨＬＯＲＩＤＥ（ＣＳＦＴＣＨ）ＩＮＲＡＢＢＩＴＳ￥ＧａｏＹｕｎｓｈｅｎｇ；ＺｈｕＹｕｙｕｎ（...