福建省龙岩市碘缺乏病病情监测结果分析

Objective To understand the current situation of iodine deficiency diserders(IDD) in Longyan City and to evaluate the effect of prevention and control measures of IDD in order to provide evidence for formulating prevention and control tactics. Methods During the year of 2006 and 2007, the 30 primary schools were screened by population proportion survey(PPS) from the 7 counties of Longyan City. Forty children aged 8-10 years in each school were randomly selected as a group to examine thyroid, and 7 children in each group were selected to measure the urine iodine and the salt iodine at the same time. The goiter rote, the median urinary iodine, the consumption rate of qualified iodized salt, the iodine salt coverage rate, the rate of qualified iodized salt and the non-iodized rate were detected. Results The goiter rate of children aged 8-10 years old in Longyan City was 0.94%(79/8438). The median urinary iodine was 259.12 μg/L. The consumption rate of qualified iodized salt was 97.86% (1462/1494). The iodine salt coverage rate was 99.46%(1486/1494). The rate of qualified iodized salt was 98.38 (1462/1486), and the non-iodized rate was 0.54% (8/1494). Conclusions All indicators have reached the national standard of eliminating IDD in Longyan City.     

异丙肾上腺素依赖型和非异丙肾上腺素依赖型血管减压性晕厥病人的治疗反应不

０８３异丙肾上腺素依赖型和非异丙肾上腺素依赖型血管减压性晕厥病人的治疗反应不同［Ｌｉｐｐｍａｎ等，ＡｍＨｅａｒｔＪ，１９９４，１２８：１１１０（英文）］直立倾斜试验（ＴＴＴ）用于检查血管减压性晕厥病人。认为ＴＴＴ阳性反应是左心窒机械感受器兴奋所造成的...     

采用滚磨术治疗5例结节性硬化症

采用滚磨术治疗５例结节性硬化症夏帮志，兰长责，吴良章；四川医学，１９９５，１６１（６）：３７１男３例，女２例，病程４～２０年，年龄１２～２５岁。５例皮损均有典型血管纤维瘤和有不同程度智力减退，但无癫痫，严重影响面容。治疗方法：面部皮损分别用０．５％淡...     

老年急性胆囊炎腹腔镜胆囊切除术42例分析

目的探讨老年人急性胆囊炎行腹腔镜胆囊切除术的可行性和手术时机的选择。方法对42例老年急性胆囊炎经腹腔镜胆囊切除的临床资料进行回顾性分析。结果经腹腔镜胆囊切除术后,除2例中转开腹手术外,其余均行腹腔镜手术成功。结论老年人急性胆囊炎经腹腔镜胆囊切除治疗如无手术禁忌证应尽早手术。     

原发后腹腔肿瘤的手术方式与肿瘤复发率和生存率相关分析

目的：探讨不同手术方法与原发性后腹膜肿瘤（PRT）的复发率和生存率关系。方法回顾性分析广西医科大学附属肿瘤医院泌尿外科2002年1月至2012年10月收治后腹腔肿瘤35例手术患者的临床资料,均行手术治疗。结果35例原发性后腹腔肿瘤经手术病理证实,良性20例,恶性15例。原发性后腹腔肿物完全切除19例（54.3%）,联合多脏器切除7例（20%）,姑息性切除6例（17.1%）,活检3例（8.6%）。整体性切除（包括A完全切除,B联合多脏器切除）与姑息性切除（包括C减瘤术,D活检术）术后1、3、5年肿瘤控制率分别为77.8%、33%,55.6%、0与11%、0（P＝0.0004）。恶性肿瘤术后3、5年生存率为74.6%、42.8%与21.2%、0（P＝0.001）。结论整体性切除是提高原发性腹膜后肿瘤控制率与生存率的关键。     

穴位敷贴加中药内服治疗慢性寻常鼻炎120例

目的用穴位敷贴疗法加中药内服治疗慢性寻常鼻炎临床疗效观察。方法将120例慢性鼻炎患者随机分为治疗组与对照组进行临床观察,治疗组用麝香斑蝥粉印堂穴位敷贴加自拟中药复方鼻炎汤口服;对照组①单用麝香斑蝥粉穴位敷贴;对照组②单服复方鼻炎汤加减。12天为一疗程,均进行1～4个疗程治疗。对各组治疗前后临床症状、体征疗效及随访结果进行观察比较。结果治疗组显效率为95%,有效率为100%;对照组①显效率为65%,有效率为85%,对照组②显效率40%,有效率为75%。治疗组的疗效明显优于各对照组。结论斑麝粉敷贴外加中药口服治疗各型慢性鼻炎疗效确切,体现了中医辨证论治的科学思维,同时表明斑麝粉敷贴疗法对于慢性鼻炎的治疗具有打通鼻、肺经络,活血消肿软坚散结、宣通肺气、调节免疫的良好作用,起着其它疗法不可替代的作用。     

低分子肝素钙预防过敏性紫癜患儿肾损害的临床观察

目的观察低分子肝素钙在预防小儿过敏性紫癜肾损害的作用。方法将73例过敏性紫癜患儿分为肝素治疗组（治疗组,39例）和对照组（34例）,治疗组给予低分子肝素钙60～100U/kg,皮下注射,1次/d,连用2周。两组患儿均同时给予基础治疗。随访期间每1周或2周检查尿常规1次。结果两组随访时间均≥3个月,治疗组发生肾炎6例（15.4%）,对照组12例（35.3%）,两组差异有统计学意义（〈0.05）;发生肾炎的时间,治疗组为发病后（91.5±43.7）d,对照组为发病后（43.9±33.5）d,两组差异有统计学意义（〈0.01）。结论肝素能预防或减少紫癜性肾炎的发生,具有显著的肾脏保护作用。     

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??Abstract??Objective??To investigate antibiotic resistance and mechanism of antibiotic resistance of Haemophilus influenzae ??HI?? in children with acute respiratory tract infection in Suzhou. To determine beta-lactamase genes of Haemophilus influenzae?? possible genetic mutation and the possible relationship between minimal inhibitory concentrations??MICs?? of beta-lactamases antibiotic and genetic mutation. Methods??The susceptibility of 135 clinical isolates of Haemophilus influenzae were calculated using E-tests?? and beta-lactamases of these stratins were detected. Besides?? the beta-lactamases genes were detected by net-polymerase chain reaction ??n-PCR?? followed by DNA sequencing. The sequences of drug resistance genes were compared with the published sequence in GeneBank. Results??The beta-lactamase positive rate of HI was 31.1%. The MIC90 and MIC50 of HI to ampicillin??ampicillin/sulbactam??cefaclor and chloramphenicol were??32 μg/mL??1 μg/mL??????2 μg/mL?? 0.75 μg/mL??????24 μg/mL??3 μg/mL?? and ??8 μg/mL??0.5 μg/mL?? respectively. Among the isolated 135?? TEM genes were detected in 53 HI. Beta-lactamase geneTEM was detected in 39.3%of HI??No ROB gene was detected. About 28.3% of TEM gene had been mutated. The mean minimal inhibitory concentration of beta-lactamases antibiotic in HI that had mutant TEM genes was higher than that of no-mutant TEM gene. Conclusion Ampicillin resistance in HI influenzae isolates from children in this region is challenging??The resistance mechanism of beta-lactamase antibiotics is of production beta-lactamase TEM and 28.3% of TEM gene has been mutated. The production of TEM and its mutation is one of the most important factors that leads to the high resistance to beta-lactamase antibiotics.     

乙肝两对半两种检测方法的比较

目前实验室检测血清乙肝两对半普遍使用酶联免疫吸附试验（ELISA）,该法具有较高的灵敏度和特异性,但操作较为繁琐、耗时较长,只能定性测定,满足临床对单纯阳性、阴性结果的判断。微粒子酶免分析技术（microparticle enzyme immu-noassay,MEIA）是一个灵敏度高、特异性强、     

64层螺旋CT儿童鼻窦低剂量扫描

目的探索64层螺旋CT低剂量扫描在儿童鼻窦中的应用,获得不同参数的辐射剂量并对图像质量进行评估。方法采用Toshiba64排螺旋CT,分别选择管电压为120和100kV时,转速O．5s／rot,螺距41,用80、40、30、20、10mA的剂量对1具儿童尸体头颅标本鼻窦进行扫描,比较不同参数时的图像质量。选取能满足临床需求的最低辐射剂量作为扫描参数。并用该参数对33例儿童鼻窦炎患者进行扫描。评价图像的质量和显示精细结构的能力。结果当毫安值从100mA降到30mA时,辐射剂量明显下降,保持30mA不变,100kV时有效cT剂量指数（CTDIv01）明显小于120kV（3．1mGy比4．8mGy）。当mA降至20mA以下,图像质量明显变差。用100kV、30mA进行33例儿童鼻窦扫描,鼻窦内各结构显示清晰,所有图像均满足临床需求。CTDIvoL平均为3．03±0．09（mGy）,剂量长度乘积（DLP）为30．63_±2．58（mGy·cm）,有效辐射剂量为0．07±0．003（mSv）,仅为常规剂量的1／10。结论采用64层螺旋CT以100kV、30mA（15mAs）作为扫描条件检查儿童鼻窦,可能是满足临床要求的最低剂量。