排序方式: 共有25条查询结果,搜索用时 15 毫秒
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2005~2007年,我们分别将胺碘酮与利多卡因用于100例无脉性室性心动过速(VT)或心室纤颤(VF)患者的急救,发现胺碘酮在预防再次出现的快速室性心律失常方面优于利多卡因。现报告如下。 相似文献
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目的 评价抗环瓜氨酸(CCP)抗体在类风湿关节炎(RA)诊断中的价值.方法 用ELISA法检测87例RA患者及69例其他自身免疫性疾病患者(对照组)血清中的抗CCP抗体浓度,用免疫透射比浊法检测类风湿因子(RF)浓度.以36例同期健康体检者作为健康对照组.比较抗CCP 抗体和RF 对 RA 诊断的敏感度及特异度.结果 抗CCP 抗体的敏感度为60.9%,RF为67.2%,差异无统计学意义(P>0.05).抗 CCP 抗体的特异度为94.2%,RF 为72.5 %,差异有统计学意义(P<0.05).两者联合检测特异性为97.1 %.结论 抗CCP 抗体在RA诊断中具有较高的特异性,可作为诊断RA的理想血清学指标.两者联合检测可提高检测的特异度. 相似文献
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目的 探讨RNA干扰GMF-β基因对脑梗死小鼠海马组织神经元凋亡及炎症水平的影响.方法 选择SPF级小鼠40只,将小鼠随机分为假手术组、模型组、control-shRNA组、GMF-β shRNA组,每组10只.建模后进行小鼠神经功能缺损评分;qRT-PCR检测小鼠脑组织GMF-β基因的mRNA表达水平;TTC染色法测... 相似文献
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替米沙坦和赖洛普利降压及对尿酸作用的比较 总被引:1,自引:0,他引:1
目的比较替米沙坦和赖洛普利的降压疗效及对血尿酸的影响。方法采用随机、平行对照研究,一组35例高血压患者给予替米沙坦40mg,qd;另一组33例给予赖洛普利5mg,bid。12周后观察疗效及不良反应。结果替米沙坦组最高血压由(169.36±10.8)(/102.92±10.47)mmHg降为(145.48±14.78)(/81.45±9.57)mmHg,P<0.05;24h平均压由(149.73±8.93)(/93.21±10.68)mmHg降为(132.24±14.40)(/83.45±9.47)mmHg,P<0.05。赖洛普利组最高血压由(168.17±10.16)(/102.63±11.29)mmHg降为(146.9±14.83)(/85.25±7.14)mmHg,P<0.05;24h平均压由(148.90±9.16)/(92.54±11.23)mmHg降为(133.47±13.08)(/83.68±8.92)mmHg,P<0.05。替米沙坦组血尿酸由(446.56±110.56)"mol/L降为(378.52±78.95)"mol/L,P<0.05;赖洛普利组血尿酸治疗前、后为(445.23±112.14)"mol/L和(437.34±113.87)"mol/L,P>0.05。结论替米沙坦和赖洛普利降压疗效相似,但替米沙坦有降低尿酸的作用,建议高血压合并血尿酸增高患者选用替米沙坦。 相似文献
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糖尿病是严重影响人类健康的疾病之一,其血管并发症是导致糖尿病患者致残致死的主要原因。C反应蛋白(CRP)是炎症的急性时相蛋白中最敏感的指标。近年的研究证实,CRP与2型糖尿病及其血管并发症有关,对2型糖尿病的预测预后有一定的价值。笔者检测了90例2型糖尿病患者血清超敏-C反应蛋白(H s-CRP)的水平变化,以探讨C反应蛋白与2型糖尿病及其血管并发症的关系。1资料与方法1.1一般资料对照组30例的查体健康者,男16例,女14例,平均年龄(56.6±6.8)岁,排除糖尿病、高血压、冠心病、脑血管病及肾脏疾病。糖尿病组90例,为2005年1月至2006年6月… 相似文献
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用核磁共振分析仪对大鼠糖尿病性白内障驰豫时间... 总被引:2,自引:1,他引:1
Nuclear magnetic resonance analysis (NMRA) was used to measure the relaxation time T1 and T2 of the protons in the different-stage-diseased lenses of rats with diabetic cataract caused by the streptozotocin, and the results were put in comparison with those obtained from the control group, showing that after one month of medication the values of T1 and T2 in the cataractous lenses are greater than those gained from the control group. The variation, as time goes on, becomes greater and greater. T1 and T2 indicate the speed of the free induction decay (FID) signals, and the variation of the FID signals are in direct proportion to that of the proton content of the samples. This shows that an increase in T1 and T2 indicates an increase in the water content in the diseased lenses, and the changes in ratio of "bound" water to free water. Such changes may be explained that the space for "bound" water is occupied by some other macromolecules, causing the alteration of the macromolecular structure, and consequently the aggregation of protein and the degeneration or dehydration or dehydration of the membrane occur, which may give rise to another scattering centre. So the scattering of the lens increases and its transparency decreases. This result is in agreement with some reports in the medical literature. As T1 and T2 are quite different in the normal and pathological tissues, and the protons are the most extensive nucleus in all biological tissues, NMR is a very important method to determine the proton relaxation time in the biological tissue and to judge if it is normal or not.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献