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31.
The purpose of the present study was to investigate the interaction between the pre-landing activities and the stiffness
regulation of the knee joint musculoskeletal system and the takeoff speed during a drop jump (DJ). Nine healthy male subjects
performed a DJ test from the height of 50 cm. The surface electromyographic (EMG) activity of the vastus lateralis (VL) muscle
was recorded to evaluate both the pre-landing and post-landing muscle activation levels. Simultaneous recording of the jumping
motion and ground reaction force was performed by a high-speed video camera (100 frames·s–1), and a force platform was employed to allow joint moment analysis. Joint stiffness was calculated by a linear regression
of the knee joint moment/angle relationship. Elasticity of the knee extensor muscle during DJ was estimated by means of a
four-element muscle model consisting of a parallel elastic component, a series elastic component (SEC), a viscous damper,
and a contractile element. DJ performance correlated positively with the positive peak power of the knee joint (P<0.01) and with the moment of the knee joint at the end of stretch (P<0.01). However, there was no significant relationship between DJ performance and the positive peak power of the ankle joint.
The knee joint moment at the end of stretch correlated with the SEC stiffness during the transmission phase from the end of
the initial impact to the onset of the concentric action (P<0.01) and with the maximum rate of isometric force development of the knee extensors (P<0.01). Multiple regression analysis showed that the SEC stiffness during the transmission phase of the knee joint can be
explained by a combination of the pre-activity of the VL muscle and the knee joint angular velocity at touchdown (F=5.76, P<0.05). These results seem to emphasize the functional significance of the pre-programmed activity for controlling the subsequent
stiffness regulation and then contributing to the performance in DJ. Thus, it can be suggested that the centrally pre-programmed
activity and the associated elastic behavior of the SEC in the knee extensor muscle in conjunction with the muscle contractile
property play a major role in regulating the performance in DJ.
Electronic Publication 相似文献
32.
S. Cheng P. V. Komi H. Kyröläinen D. H. Kim K. Häkkinen 《European journal of applied physiology》1989,59(1-2):128-130
Summary Vibrational wave propagation was tested in vivo on the tibial bone of both legs of 56 female volunteers. The impact was produced
by a hammer with a force strain gauge and the response was monitored by two accelerometers. The peak amplitude of the accelerations,
the velocity of the acceleration wave propagation and damping were analysed for comparison among the different age groups.
The results showed significant negative correlations between age and the peak amplitude of acceleration, and the velocity
of acceleration wave propagation (p<0.01). The damping time of the acceleration wave also had a negative correlation with age. These findings suggested that
age differences were related to the differences in the mechanical properties of bone. With reduction of bone mineral density,
the velocity of the vibrational wave propagation would decrease, with simultaneous increase in impedance. In addition, wave
absorption would be accelerated. It is suggested that this method could be used as an indicator of bone density. The method
could also be developed to provide an index to monitor the progress of osteoporosis.
Visiting research assistant from the Department of Sport Medicine, Chengdu College of Physical Education, Chengdu, People's
Republic of China
Visiting research assistant from Seoul National University, Seoul, South Korea 相似文献
33.
This study invokes the ecological approach to social support by examining how school social support relates to moderate or severe adolescent depression. School is seen as not only a place for supportive individual‐level relationships, but also as a source of community support created by teachers and other students. The main purpose of the study is to examine whether school‐level social support is related to adolescent depression and, if so, how much of the school‐level differences in moderate or severe adolescent depression can be explained by school social support? The study is based on data included in the Finnish School Health Promotion Survey, which covers about 70% of Finnish 14‐ to 16‐year‐old adolescents. The data were collected in 2002–2003 and the analysis was conducted by employing multilevel logistic regression analysis. © 2008 Wiley Periodicals, Inc. 相似文献
34.
35.
Multilaboratory Evaluation of a Viability Assay for Measurement of Opsonophagocytic Antibodies Specific to the Capsular Polysaccharides of Streptococcus pneumoniae 下载免费PDF全文
Sandra Romero-Steiner Carl Frasch Nelydia Concepcion David Goldblatt Helena Kyhty Merja Vkevinen Craig Laferriere Dominique Wauters Moon H. Nahm Mark F. Schinsky Brian D. Plikaytis George M. Carlone 《Clinical and Vaccine Immunology : CVI》2003,10(6):1019-1024
Opsonophagocytosis is a correlate of protection that measures the functional activity of vaccine-induced antibodies. A standardized opsonophagocytosis assay (OPA) should be used as part of the evaluation of current and future pneumococcal (Pnc) polysaccharide (Ps)-based vaccines. We enrolled five laboratories to evaluate a previously standardized viability OPA. Each laboratory was provided with a detailed OPA protocol, seven target Pnc strains (serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F), two quality control sera and 12 paired sera (blinded) from adult donors who received one dose of the 23-valent Pnc Ps vaccine. Laboratories sent their results to the Centers for Disease Control and Prevention for analysis. Sera were tested in duplicate (single run), and the results were averaged to yield a single OPA titer (≥50% killing) for each serum sample. The percentage of sera within one or two dilutions of the calculated median OPA titer was determined for each laboratory and for each serotype. In general, laboratories were capable of detecting OPA titers within one or two dilutions of the median for at least 75 and 88%, respectively, of the sera tested. The level of agreement with the median OPA titers varied depending on the participating laboratory (overall agreement = 0.8 [99% confidence interval = 0.75 to 0.85]). All OPA median titers reported for quality control sera were within one dilution of the expected titer. We conclude that this OPA can be done in multiple laboratories with a high degree of interlaboratory reproducibility. 相似文献
36.
Järvinen O Hietala M Aalto AM Arvio M Uutela A Aula P Kääriäinen H 《Clinical genetics》2000,58(6):447-454
Genetic carrier testing of children is usually not recommended. However, there are no data concerning long-term psychological consequences, experience, and satisfaction of those tested as well as their recall of the test results. We evaluated these items retrospectively 10–24 years after carrier testing performed in childhood. Study material comprised 25 families with aspatylglucosaminuria (AGU), an autosomal recessive disorder, with 35 healthy sibs from all parts of Finland tested for carriership during childhood between 1973 and 1987. Of these sibs, 25 participated in our study. The questionnaire comprised multiple-choice and open-ended questions. The psychosocial well-being of the study subjects measured by the RAND 36 item Health Survey 1.0 (RAND) was, in general, at least as good as that of controls, and showed no significant differences between carriers and non-carriers (p>0.154). All tested individuals were satisfied with the fact that they had been tested and stated that the decision to perform carrier testing on a child can be made by the parents. Of the 25 tested, 23 knew and understood their test result correctly at the time of our study. Most of the tested individuals (60%) stated that the best time for carrier testing would be in the childhood or in the teen years.
This study indicates that carrier testing in childhood for an autosomal recessive disorder (AGU) had caused no measurable disturbance of quality of life in adulthood, and those tested reported being satisfied. However, we do not recommend testing in childhood, as the result is not needed prior to the time for reproductive decisions. 相似文献
This study indicates that carrier testing in childhood for an autosomal recessive disorder (AGU) had caused no measurable disturbance of quality of life in adulthood, and those tested reported being satisfied. However, we do not recommend testing in childhood, as the result is not needed prior to the time for reproductive decisions. 相似文献
37.
Bacterial cell wall-induced arthritis: chemical composition and tissue distribution of four Lactobacillus strains 下载免费PDF全文
To study what determines the arthritogenicity of bacterial cell walls, cell wall-induced arthritis in the rat was applied, using four strains of Lactobacillus. Three of the strains used proved to induce chronic arthritis in the rat; all were Lactobacillus casei. The cell wall of Lactobacillus fermentum did not induce chronic arthritis. All arthritogenic bacterial cell walls had the same peptidoglycan structure, whereas that of L. fermentum was different. Likewise, all arthritogenic cell walls were resistant to lysozyme degradation, whereas the L. fermentum cell wall was lysozyme sensitive. Muramic acid was observed in the liver, spleen, and lymph nodes in considerably larger amounts after injection of an arthritogenic L. casei cell wall than following injection of a nonarthritogenic L. fermentum cell wall. The L. casei cell wall also persisted in the tissues longer than the L. fermentum cell wall. The present results, taken together with those published previously, underline the possibility that the chemical structure of peptidoglycan is important in determining the arthritogenicity of the bacterial cell wall. 相似文献
38.
N. Forss R. Hari R. Salmelin A. Ahonen M. Hämäläinen M. Kajola J. Knuutila J. Simola 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1994,99(2):309-315
We recorded somatosensory evoked magnetic fields from ten healthy, right-handed subjects with a 122-channel whole-scalp SQUID magnetometer. The stimuli, exceeding the motor threshold, were delivered alternately to the left and right median nerves at the wrists, with interstimulus intervals of 1, 3, and 5 s. The first responses, peaking around 20 and 35 ms, were explained by activation of the contralateral primary somatosensory cortex (SI) hand area. All subjects showed additional deflections which peaked after 85 ms; the source locations agreed with the sites of the secondary somatosensory cortices (SII) in both hemispheres. The SII responses were typically stronger in the left than the right hemisphere. All subjects had an additional source, not previously reported in human evoked response data, in the contralateral parietal cortex. This source was posterior and medial to the SI hand area, and evidently in the wall of the postcentral sulcus. It was most active at 70–110 ms. 相似文献
39.
40.
Hämäläinen O Toivakka-Hämäläinen SK Kuronen P 《Aviation, space, and environmental medicine》1999,70(4):330-334
Previous magnetic resonance imaging (MRI) studies have shown that repeated exposure to +Gz forces can cause premature degenerative changes of the cervical spine (i.e. a work-related disease). This paper reports on two clinical cases of +Gz-associated degenerative cervical spinal stenosis caused by dorsal osteophytes in fighter pilots. Conventional x-rays and MRI were used to demonstrate narrowing of the cervical spinal canal. The first case was complicated by a C6-7 intervertebral disk prolapse and a congenitally narrow spinal canal. The second case involved progressive degenerative spinal stenosis in the C5-6 disk space which required surgery. The findings in this case were confirmed by surgery which showed posterior osteophytes and thickened ligaments compressing the cervical medulla. These two cases suggest that +Gz forces can cause degenerative spinal stenosis of the cervical spine. Flight safety may be jeopardized if symptoms and signs of medullar compression occur during high +Gz stress. It is recommended that student fighter pilots undergo conventional x-rays and MRI studies in order to screen out and reject candidates with a congenitally narrow spinal canal. These examination methods might be useful in fighter pilots' periodic medical check-ups in order to reveal acquired degenerative spinal stenosis. 相似文献