异种烧结骨修复颌骨缺损的临床观察

本文报告了应用异种烧结骨修复颌骨缺损25例,采用手术前后X线及免疫学、r骨显像等观察,进行了较系统的临床研究.经6～12个月追踪观察,结果表明:创口愈合正常,未见免疫排斥反应.术后3周左右植骨成活,2～3个月有新骨形成、与空白对照组比较,烧结骨有明显加快骨缺损部位成骨作用,新生骨出现早,成骨速度快.证实烧结骨具有良好的组织相容性和骨传导能力,具有较高的临床实用性,是一种较理想的骨移植材料.     

双抗胶原膜的临床抗菌抗降解观察

目的：评估自行研制用于引导牙周组织再生（ＧＴＲ）的双抗胶原膜（ＢＡＣＭ）在临床应用中实际抗菌能力和抗酶解性能。方法：对１２例牙周炎患者行体内药物释放试验，以高效液相色谱测其龈沟液四环素含量；应用扫描电镜观察ＧＴＲ术后１周取出的ＢＡＣＭ膜上的细菌附着情况。结果：牙周袋内放置四环素１５０μｇ，１周后龈沟液中药物浓度为２０．７８μｇ／ｍｌ，扫描电镜观察胶原膜纤维结构完好无损，ＢＡＣＭ上细菌数明显少于对照膜（ＧＬＣＭ）。结论：临床评估ＢＡＣＭ能显著减少细菌对胶原膜的附着，并具有一定抗胶原酶的性能。     

两种抗肿瘤药物影响生物陶瓷人工骨与骨结合的研究

为了探讨抗肿瘤药平阳霉素(BLM)及氨甲喋呤(MTX)对生物陶瓷人工骨与骨结合的作用,作者以杂种狗为种植模型,采用定量组织测量学、生物力学、元素分析的定量分析方法考察了骨与人工骨的结合区.结果发现在植入后1.5月MTX不仅能抑制局部新骨的生长与钙化,而且能减少骨与人工骨的结合,从而降低了人工骨植入体的稳定性.而同期BLM上述作用却不明显,因此作者认为对于肿瘤术后人工骨修复的患者的术后化疗拟应用BLM为宜.     

Transmigration of permanent mandibular canines. Case report

Transmigration is the migration of a tooth across the midline of the jaw. This phenomenon is found only in relation to the permanent mandibular canines. Two cases are reported. In both, the cause of this deviation was an odontome found in the site normally occupied by the mandibular canine. The literature on transmigration is reviewed.     

种植义齿系统工程的概念及修复环节在其中的位置

种植义齿治疗是一个系统工程，需要医学专家、理工专家和患者的共同努力。其中，修复专家占有重要地位。他们需要根据患者的意愿和条件确定种植义齿是否可行，以及是否能给患者带来最大的利益。需要设计植入体的数量、部位和植入角度。需要根据种植体界面的特殊条件在义齿的设计制作中作相应的处理。还需要对患者作咨询教育，使之对种植义齿抱有合理的期望并遵医嘱执行保健措施。     

口腔白斑、扁平苔藓细胞凋亡相关蛋白Bax表达的研究

目的 :探讨口腔白斑、扁平苔藓的癌变机理及发病机制。方法 :采用免疫组化法检测 10例正常口腔黏膜上皮 ,18例扁平苔藓 ,2 3例白斑 ,2 2例口腔鳞癌上皮组织中凋亡相关蛋白Bax的表达水平。结果 :白斑中上皮单纯增生、轻度、中度不典型增生和低分化鳞癌及糜烂型扁平苔藓的Bax蛋白显过度表达 ,与正常口腔黏膜上皮相比有显著性差异。结论 :Bax参与了口腔白斑癌变的早期过程 ,Bax的表达水平可作为临床监测白斑癌变倾向的参考指标。扁平苔藓的发病机制可能与细胞免疫亢进刺激Bax过度表达诱导角朊细胞凋亡有关 ,扁平苔藓的癌变机理有待进一步研究     

Guidelines for infection control in dental health care settings--2003

BACKGROUND: The Centers for Disease Control and Prevention, or CDC, is the lead federal agency for disease prevention in the United States. It has been 10 years since CDC infection control guidelines for dental health care settings were last published. During those 10 years, new technologies and issues have emerged, and other CDC infection control guidelines for health care settings have been updated. RESULTS: In light of these developments, CDC collaborated with experts in infection control to revise its infection control recommendations for dental health care settings. Existing guidelines and published research pertinent to dental infection control principles and practices were reviewed. This article provides background information, describes the process used to create these guidelines, and lists the new recommendations. CLINICAL IMPLICATIONS: CDC believes that dental offices that follow these new recommendations will strengthen an already admirable record of safe dental practice. Patients and providers alike can be assured that oral health care can be delivered and received in a safe manner.