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81.
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Milan Hora Petr Stránský Ivan Trávníček Tomáš Ürge Viktor Eret Boris Kreuzberg Jan Baxa Hynek Mírka Fredrik Petersson Ondřej Hes Jiří Ferda 《World journal of urology》2013,31(5):1171-1176
Purpose
The new generation of 3TMRI has improved spatial and time resolutions, which are favourable in imaging of the renal vasculature. In this study, we have compared the imaging findings of the renal blood vessels using 3TMRI and CT with intraoperative assessment of the renal vasculature as gold standard.Methods
This prospective study was approved by the local ethical committee. Between 4/2011 and 12/2011, 80 patients with renal tumours underwent 3TMRA (angiography) (Magnetom SKYRA 3T, Siemens). Twenty of the patients were also examined with CT AG. The results of the CTA- and MRA-imaging studies were correlated with the intraoperative assessment of the renal vessels.Results
Seventy patients (87.5 %) had a detailed intraoperative assessment of the renal vessels. The sensitivities for CTA and MRA were 88.2 and 88.6 %, respectively. All discrepancies between imaging studies and intraoperative findings were due to inability to identify small polar vessels. The results of MRA were concordant with CTA in 85.0 % of cases. The (three) discrepancies between MRI and CT were due to failure of MRI in identifying small polar vessels.Conclusions
(1) 3TMRA gives detailed information about the renal vasculature including its topographical anatomy. (2) With MRI, small aberrant vessels are more frequently missed than with CTA. (3) CTA remains the gold standard. However, MRA may be used for planning of laparoscopic operations. (4) The quality of the 3D reconstruction is highly depending on the skills of the radiologist. 相似文献83.
Vladan Stevanović Zoran Blagojević Agnica Petković Miodrag Glišić Jelena Sopta Valentina Nikolić Milan Milisavljević 《International orthopaedics》2013,37(12):2475-2481
Purpose
It has been demonstrated that the semitendinosus tendon can regenerate after being harvested in its whole length and thickness for anterior cruciate ligament (ACL) reconstruction. Ultrasound studies and guided biopsies of the regenerated tendon have shown compatibility and resembling features of the normal tendon. The question is if this neo-tendon is biologically and functionally adequate for re-use?Methods
Two randomised groups of 150 volunteers were followed up for two years after harvesting the semitendinosus only (25) or the semitendinosus and gracilis tendons (25) in ACL reconstruction. The patients were followed up with clinical and ultrasound examinations, biopsies and histological tests. Surgical exploration was done in three patients for macroscopic verification. The injected arteries of four lower limbs were dissected and the tendon’s arterial supplies were examined.Results
Seventy-two percent of the cases showed regeneration of the semitendinosus tendons. The neotendons were inserted mostly below the knee joint (83.3 %) where they had fused with the gracilis tendon, and above the joint (60 %) when the gracilis was harvested as well. The isokinetic strength of the hamstrings and quadriceps was not significantly diminished on the operated side. A macroscopic and histological analysis of the regenerated tendons demonstrates close resemblance to normal anatomy, with focal areas of fibrosis. In one patient the regenerated tendon was used for medial patellofemoral ligament reconstruction.Conclusion
The semitendinosus muscle can recover and the tendon has great potential to regenerate after harvesting for ACL reconstruction. Our data suggest that the regenerated tendons could be used for iterative ligament reconstruction. 相似文献84.
Nikos C. Stefanis Milan Dragovic Brian D. Power Assen Jablensky David Castle Vera Anne Morgan 《Schizophrenia bulletin》2013,39(2):251-254
We investigated the existence of a temporal association between age at initiation of cannabis use and age at onset of psychotic illness in 997 participants from the 2010 Survey of High Impact Psychosis (SHIP) in Australia. We tested for group differences in age at onset of psychotic illness and in the duration of premorbid exposure to cannabis (DPEC). Analyses were repeated in subgroups of participants with a schizophrenia-spectrum disorder (SSD), a diagnosis of lifetime cannabis dependence (LCD), and a comorbid SSD/LCD diagnosis. The association between age at initiation of cannabis use and age at onset of psychotic illness was linear and significant, F(11, 984) = 13.77, P < .001, even after adjusting for confounders. The effect of age at initiation of cannabis use on DPEC was not significant (mean duration of 7.8 years), and this effect was similar in participants with a SSD, LCD, and comorbid SSD/ LCD diagnosis although a shift toward shorter premorbid exposure to cannabis was noted in the SSD/LCD subgroup (mean duration of 7.19 years for SSD/LCD). A temporal direct relationship between age at initiation of cannabis use and age at onset of psychotic illness was detected with a premorbid exposure to cannabis trend of 7–8 years, modifiable by higher severity of premorbid cannabis use and a diagnosis of SSD. Cannabis may exert a cumulative toxic effect on individuals on the pathway to developing psychosis, the manifestation of which is delayed for approximately 7–8 years, regardless of age at which cannabis use was initiated.Key words: cannabis, psychosis, schizophrenia, age at onset, causality, DIP, SHIP 相似文献
85.
86.
Chlebus P Mikl M Brázdil M Pazourková M Krupa P Rektor I 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》2007,179(3):365-374
Several functional MR imaging studies evaluating the lateralisation of linguistic functions in patients who underwent Wada
testing have been reported. There is extensive variance in the Laterality index (LI) calculation across the studies, and the
optimal calculation method remains unclear. We attempted to calculate the LI in different ways in the same subjects, in order
to find the LI calculation method with the highest correlation to the Wada test. Fifteen patients (10 females, 5 males) suffering
from medically intractable temporal lobe epilepsy (TLE) (12 left, 3 right) were admitted for the study. The patients underwent
a standardized bilateral intracarotid short-acting barbiturate test. Language testing included spontaneous speech, oral comprehension,
reading, object and picture naming, and repetition. All the tasks were scored separately in order to increase the possibility
of correlation between Wada and LI. A silent phonemic verbal fluency task (VFT) was used as a language paradigm for functional
measurement. Regions of interest (ROIs), with a known association with language function (Broca’s area, the lateral prefrontal
cortex, etc.), were defined. First, the LIs were calculated from the ROIs using a previously reported method (simple suprathreshold
count). Next, we used several new methods of LI calculation (t–weighting of voxels, methods independent of the choice of the statistical threshold, etc.) The most significant correlation
with Wada was proven in the LIs that were evaluated from Broca’s area (up to R = 0.94, P = 1 × 10−7). However, the new LI calculation methods used in the present study did not produce a statistically significant benefit in
comparison to previously reported methods. 相似文献
87.
88.
Biological evaluation of selected 3,4‐dihydro‐2(1H)‐quinoxalinones and 3,4‐dihydro‐1,4‐benzoxazin‐2‐ones: Molecular docking study 下载免费PDF全文
Jelena Petronijević Nenad Janković Tatjana P. Stanojković Nenad Joksimović Nađa Đ. Grozdanić Milan Vraneš Aleksandar Tot Zorica Bugarčić 《Archiv der Pharmazie》2018,351(5)
89.
Alexandra Kmetova Eva Kralikova Lenka Stepankova Kamila Zvolska Milan Blaha Michal Sticha Zbynek Bortlicek Darrell R. Schroeder Ivana T. Croghan 《Addictive behaviors》2014
Objective
To identify possible predictors of post-cessation weight gain in smoking abstainers.Patients and methods
A sample of 607 successful abstainers seen at the Centre for Tobacco-Dependent in Prague, Czech Republic, between 2005 and 2010, was included in this analysis. This sample was followed up for 1 year and included 47.9% women (N = 291) with the mean age of 48 years (18–85).Findings
Post-cessation weight gain occurred in 88.6% of the 607 abstainers. The mean weight gain after one year post-quit was 5.1 kg (95% confidence interval 4.7–5.5 kg). Baseline characteristics associated with increased weight gain included a higher baseline smoking rate (p < 0.001), more severe cigarette dependence (p = 0.003), less physical activity (p = 0.008), and a report of increased appetite on the baseline assessment of withdrawal symptoms (p < 0.001).Conclusions
Smokers who are more dependent and have minimal physical activity are at increased risk for post-cessation weight gain. For these smokers, incorporating interventions targeting the weight issue into tobacco dependence treatment is recommended. Further research should be done to identify reasons for this important quitting complication. 相似文献90.
Lenka Kucharikov Denisa Medveck Eva Tillov Juraj Belan Michaela Kritikos Mria Chalupov Milan Uhrí
ik 《Materials》2021,14(8)
Secondary-cast aluminum alloys have increasing industrial applications. Their biggest deficiency is their impurity content, especially Fe, which has low solubility in Al and almost all the content creates intermetallic phases. This work examines the effect of higher Fe content on the microstructure and properties of A356.0 alloy. At the same time, no other possibility existed to affecting the brittleness of the formation of the β phases. The calculation of Fecrit, ratio of Mn/Fe, quantitative and computed tomography analysis of porosity and Fe plate-like phases, measurement of mechanical and fatigue properties, and fractography analysis were performed in this study. The results show that gravity die casting into a sand mold, and the non-usage of Mn addition or heat treatment, do not have a negative effect on increasing the size of the Fe-rich plate-like phases. The longest Fe-rich phases have limited the pore growth and ratios, but their higher thickness led to greater porosity formation. The mechanical and fatigue properties correlate with the Fecrit level and the highest were for the experimental alloy with 0.454 wt.% of Fe. The experimental results confirmed the fact that if the Fe plate-like phases have a length of up to 50 µm, the fatigue properties depend more on the size of porosity. If the length of the Fe needles is more than 50 µm, then the properties are mainly affected by the length of these Fe phases. 相似文献