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排序方式: 共有421条查询结果,搜索用时 15 毫秒
121.
Acoustic neuromas: Gd-DTPA enhancement in MR imaging 总被引:1,自引:0,他引:1
Magnetic resonance (MR) imaging examinations were performed in ten patients with 12 acoustic neuromas before and after intravenous administration of 0.1 mmol/kg body weight gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). The degree of enhancement was greatest with the inversion recovery sequence 1,500/500/44 (repetition time [TR]/inversion time/echo delay time [TE]), followed by spin-echo (SE) 544/44 (TR/TE) sequences, then by SE 1,500/44 and SE 1,500/80 sequences. After enhancement there was a 50% reduction for measured T1 values, 33% for T2, and no significant change for proton density. There were no toxic effects on patients. Enhanced CT scans failed to demonstrate lesions in six of 12 cases. Air-CT technique improved sensitivity in four of five cases. Enhanced MR imaging added significant clinical information in two small intracanalicular tumors and in one recurrent tumor. 相似文献
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Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro 总被引:9,自引:1,他引:8
Kizaki M; Dawson MI; Heyman R; Elster E; Morosetti R; Pakkala S; Chen DL; Ueno H; Chao W; Morikawa M; Ikeda Y; Heber D; Pfahl M; Koeffler HP 《Blood》1996,87(5):1977-1984
124.
A digital imaging system that employs a novel scanning x-ray tube, a multiple-slit assembly (MSA), and an image intensifier (II)-TV digital system is described. Use of the MSA can increase x-ray utilization by a factor of 100 over that obtained with single-slit systems. Scatter and veiling glare can be reduced substantially by synthesizing the final image from a number of multiple-slit images, resulting in improvement in contrast sensitivity. An experimental prototype system consisted of a conventional x-ray tube and an II-TV digital system used in conjunction with mechanical scanning of the MSA. Attenuation curves measured with an aluminum stepwedge showed that scatter and veiling glare were eliminated by this approach. Reconstructed images of phantoms were superior to images obtained with conventional wide-beam exposure. Physical parameters related to design of the scanning x-ray tube and a digital system for acquiring images of the chest are discussed. 相似文献
125.
Blood pressure independent effects of nitrendipine on cardiac structure in patients after renal transplantation 总被引:2,自引:2,他引:0
Rockstroh JK; Schobel HP; Vogt-Ladner G; Hauser I; Neumayer HH; Schmieder RE 《Nephrology, dialysis, transplantation》1997,12(7):1441-1447
Left ventricular hypertrophy is well established as a blood pressure
independent cardiovascular risk factor in patients on renal replacement
therapy. The effects of antihypertensive treatment on myocardial structure
and function in renal transplant recipients have been so far only rarely
investigated. In a double-blind, placebo-controlled study patients were
randomized to the calcium channel blocker nitrendipine or placebo if the
transplanted kidney had developed a stable phase. Normotensive patients
received nitrendipine 2 x 5 mg daily or placebo, hypertensive patients
received 2 x 10 mg up to 2 x 20 mg nitrendipine daily or placebo. To
achieve adequate blood pressure control, all patients with still elevated
blood pressure on study medication received antihypertensive drugs other
than calcium channels blockers. Ambulatory blood pressure recording and
2D-guided M-mode echocardiography were performed at baseline and upon
completion of the study. In addition, laboratory workup (including serum
creatinine and lipids) was done, and serum aldosterone, plasma renin
activity, plasma angiotensin II and blood glucose levels were measured in
all patients at baseline and after at least 12 months of therapy.
Ambulatory blood pressure was almost identical between both groups at study
baseline and follow-up. In renal transplant patients on nitrendipine,
posterior wall thickness (-0.10 +/- 1.77 mm) and septal wall thickness
(-0.83 +/- 2.23 mm) did not change significantly from baseline. In
contrast, posterior wall thickness (0.71 +/- 0.92 mm, P < 0.01) and
septal wall thickness (0.97 +/- 2.20 mm, P < 0.05) increased in patients
on placebo, which differed from the observed changes on nitrendipine
(ANOVA: P = 0.093 and P = 0.048, respectively). Relative wall thickness, a
parameter for concentric left ventricular hypertrophy, became numerically
smaller on nitrendipine therapy from 0.46 +/- 0.07 to 0.44 +/- 0.09 (-0.02
+/- 0.09, NS) but increased from 0.42 +/- 0.08 to 0.48 +/- 0.08 in the
placebo arm (+0.04 +/- 0.08, P < 0.02), which was also significant
between the two groups (ANOVA: P = 0.036). Endocrine parameters, lipids and
blood glucose were not different between the two groups. We conclude from
these data that the calcium channel blocker nitrendipine exerted beneficial
effects on cardiac structure in patients after renal transplantation
independent of blood pressure.
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Finkelstein JA Zaveri G Wai E Vidmar M Kreder H Chow E 《The Journal of bone and joint surgery. British volume》2003,85(7):1045-1050
The management of spinal metastases is palliative and aimed at improving quality of life at an acceptable risk. This population study uses administrative databases and measures survivorship and complication rates after surgery for spinal metastases. The effects of various potential predictor variables were evaluated. We identified 987 patients with a median survival for all types of cancer of 227 days. The one and three-month mortality was 9% and 29%, respectively. Increasing age, male gender and primary lung cancer were significant risk factors for death within 30 days of surgery. A preoperative neurological deficit contributed a 19% increase in mortality and a 71% increase in the risk of postoperative wound infection. We found an overall major complication rate of 27%. This information will provide patients, families and clinicians with objective data which will help in the choice of treatment and the understanding of the surgical risk and outcome. 相似文献